> list.of.packages <- c("xlsx", "kableExtra", "dplyr", "ggplot2", "egg", "cowplot",
+ "patchwork", "gridExtra", "UsingR", "car", "lattice", "ggpubr", "ggbreak", "GGally",
+ "reshape2", "ggcorrplot", "corrplot", "rela", "ggrepel", "factoextra", "sparsepca")
> new.packages <- list.of.packages[!(list.of.packages %in% installed.packages()[, "Package"])] ## check for packages not installed
> if (length(new.packages)) install.packages(new.packages) ## install packages if necessary
> res <- unlist(lapply(list.of.packages, require, character.only = T)) ## load packages needed for the session
> if (any(res == F)) {
+ list.of.packages[which(res == F)] ## show those package if you have troubles to install.
+ }
>
> list.of.bioc.packages <- c("phyloseq", "pcaMethods")
> new.packages.bioc <- list.of.packages[!(list.of.bioc.packages %in% installed.packages()[,
+ "Package"])]
> if (length(new.packages.bioc)) BiocManager::install(new.packages.bioc)
> res.bioc <- unlist(lapply(list.of.bioc.packages, require, character.only = T))
> if (any(res.bioc == F)) {
+ list.of.packages[which(res.bioc == F)] ## show those package if you have troubles to install.
+ }> resumen <- function(x) {
+ c(round(mean(x), 4), round(sd(x), 4))
+ } # Function that help us to summarize the data in mean and sd values
> lowerFn <- function(data, mapping, method = "lm", ...) {
+ p <- ggplot(data = data, mapping = mapping) + geom_point(colour = "blue") + geom_smooth(method = method,
+ color = "red", ...)
+ p
+ }
>
> ## Function that takes variable names and the labels for the axis.
> bp.1.vars <- function(datos_, vars, y_lab) {
+
+ datos <- cbind(datos_[, c("GROUP", "OBESE")], datos_[, vars])
+ df.melt <- melt(datos, id.vars = c("GROUP", "OBESE"))
+
+ # print(head(df.melt))
+
+
+ p2 <- ggplot(df.melt, aes(y = value, x = variable, fill = GROUP)) + geom_boxplot() +
+ ylab(y_lab) + facet_grid(~OBESE) + xlab("") + geom_hline(yintercept = 0,
+ linetype = "dashed", color = "red")
+
+
+ return(p2)
+
+ }
>
> plotPCA_sparse <- function(pcX, factor, title, size = 1.5, glineas = 0.25, labels,
+ plot.scores = T) {
+
+ X.scores <- pcX$scores
+ colnames(X.scores) <- paste0("PC", 1:dim(X.scores)[2])
+ X.loads <- pcX$loadings
+ colnames(X.loads) <- paste0("PC", 1:dim(X.scores)[2])
+ rot <- round(pcX$sdev^2/sum(pcX$sdev^2) * 100, 2)
+ if (plot.scores == T) {
+ # scores
+ X.scores <- as.data.frame(X.scores)
+ Group <- factor[[1]]
+ Group2 <- factor[[2]]
+ colores <- 1:length(levels(Group))
+ # main plot
+ p1 <- ggplot(X.scores, aes(x = PC1, y = PC2)) + theme_classic() + geom_hline(yintercept = 0,
+ color = "gray70") + geom_vline(xintercept = 0, color = "gray70") + geom_point(aes(color = Group,
+ shape = Group2), alpha = 0.55, size = 3) + coord_cartesian(xlim = c(min(X.scores[,
+ 1]), max(X.scores[, 1]))) + scale_fill_discrete(name = "Group")
+ # avoiding labels superposition
+
+ grafico <- p1 + geom_text_repel(aes(y = PC2 + 0.25, label = labels), segment.size = 0.25,
+ size = size) + labs(x = c(paste("PC1", rot[1], "%")), y = c(paste("PC2",
+ rot[2], "%"))) + ggtitle(paste("Principal Component Analysis for: ",
+ title, sep = " ")) + theme(plot.title = element_text(hjust = 0.5)) +
+ scale_color_manual(values = colores)
+ } else {
+
+ X.loads <- as.data.frame(X.loads)
+ # main plot
+ p1 <- ggplot(X.loads, aes(x = PC1, y = PC2)) + theme_classic() + geom_hline(yintercept = 0,
+ color = "gray70") + geom_vline(xintercept = 0, color = "gray70") + geom_point(aes(color = "gray70"),
+ alpha = 0.55, size = 3) + coord_cartesian(xlim = c(min(X.loads[, 1]),
+ max(X.loads[, 1])))
+ # avoiding labels superposition
+
+ grafico <- p1 + geom_text_repel(aes(label = labels), segment.size = 0.25,
+ size = size) + labs(x = c(paste("PC1", rot[1], "%")), y = c(paste("PC2",
+ rot[2], "%"))) + ggtitle(paste("Principal Component Analysis for: ",
+ title, sep = " ")) + theme(plot.title = element_text(hjust = 0.5)) +
+ theme(legend.position = "none")
+
+ }
+
+ return(list(pcX, grafico))
+ }Summary of the univariate descrpitve analysis.
Overall study.
The data comprises 53 subjects, which are divided into 34 females and 19 males. From the 34 females, 18 are non obese and 16 obese. And 10 non obese males and 9 obese males. The 18 non obese females are divided into 9 PCOS and 9 healthy. The 16 obese females are divided further into 8 PCOS and 8 non PCOS.
A sanity check of the study was performed to observed possibly differences between the groups. No differences were found. Descriptive numerical tables were performed on each data-set except on the microbiome. Numerical descriptive tables only contain the mean and the standard deviation.
For each numerical variable (all except the ones that describes the groups) their distribution were analyzed as a whole, without taking into account the groups (obese, sex and PCOS).
It has to be mentioned that no correlation between variables on the different data types were performed. Only uni variate statistical analysis on each data set was performed.
Permeability markers, and some clinical biomarkers, were analyzed at basal and postprandial times. The first day of the study corresponds to the glucose oral load, the second to the lipids and the third to the proteins.
Clinical data: Comprises 63 variables. The first variable is the order of the data, the second variable is the sample name, and the next 5 variables belong to sex, group (female, male, PCOS), obese (whether obese or not obese), age and BMI, WC, WHR. And 54 biomarkers. From those 54 biomarkers, there are testosterone, estradiol, its ratio, HOMA-IR, ISI, cholesterol, HDL , LDL, insulin and glucose. Sex steroids, the ratio, HOMA-IR and ISI are only calculated at basal levels. The other variables are calculated also at postprandial level. Furthemore the levels of all these variables the mean basal value for each day of the study is computed.
Permability Biomarkers: Apart from the categorical variables, we have sCD14, LBP, zonulin and succinate. Each variable the mean basal value is computed,as well as the basal values for each day and the postprandial stage. Succinate is more like a metabolite, however, it was calculated in other units, and we do not know how to include this metablolite. ( No units are specified on this data set)
Metabolome: The data includes only the sample and the order. And 261 variables. From these variables, only 37 were actually metabolites. The other variables belong to the mean basal values, the basal values for each day, and the postprandial values for each day.
4.Microbiome. Here, we have two sets of data. Reads from the several phylum and the genus. Only 5 subjects could not be able to analyze their faces. We performed a sanity check of the data to observe if this variation in the data affected the study. It did not.
Metabolome
This data set was analyzed in a different way. Instead of referring at the literature, because, each metabolite is associate with many pathways, and the fact that most of them are aminoacids, we performed a correlation matrix plot. From this plot, we infer that the correlations, whether positive or negative, may be due to the physical/chemical properties.
For instance, Oxoisocaproic, Leucine, Isoleucine and Valine are positive correlated. These metabolites have in common that the Oxoisocaproic acid, is derived from the leucine, isoleucine, and valine. And leucine, isoleucine and valine are non-polar.
Normal and non-normal, i.e skewed distributions were found across all mean basal values of metabolites. For each metabolite, descriptive analysis of box plot was performed. In general postprandial levels of each metabolite were lower than basal values.
Description of the metabolites.
Read the file of the metabolome. The data as the other datasets, are in excel format. Furthermore, sheet 2 , gives information about the encoding of the metabolites. There is a row of NA because of the import, so we remove that row. Then this dataset, the sample names have a different name than the Intestinal Permeability, and Clinical variables data-sets.
On the metabolome data, the GROUP and OBESE variables are not in there. Thus we have to extract from the clinical data.
> general <- file.path(params$folder.data, file = params$file.general) ## file path of the data
> general_data <- read.xlsx(general, sheetIndex = 1) ## data
>
> general_data$SEX <- factor(general_data$SEX, levels = c(0, 2), labels = c("Female",
+ "Male"))
> general_data$OBESE <- factor(general_data$OBESE, levels = c(0, 1), labels = c("No Obese",
+ "Obese"))
> general_data$GROUP <- factor(general_data$GROUP, levels = c(0, 1, 2), labels = c("Female",
+ "PCOS", "Male"))
> GROUP <- general_data$GROUP
> OBESE <- general_data$OBESE> metabolome_file <- file.path(params$folder.data, file = params$file.data) ## file path of the data
> metabolome.tmp <- read.xlsx(metabolome_file, sheetIndex = 1) # read the data
> metabolites_name <- read.xlsx(metabolome_file, sheetIndex = 2)$Metabolitos # read the names of the metabolites
> any(is.na(metabolome.tmp)) # there is a row of missing values.[1] TRUE> metabolome <- metabolome.tmp[-nrow(metabolome.tmp), ] ## remove the missing value row
> metabolome$GROUP <- general_data$GROUP ## add GROUP variable
> metabolome$OBESE <- general_data$OBESE ## add OBESE variables.Observe the structure of the data
> str(metabolome) # show general description of the data'data.frame': 53 obs. of 263 variables:
$ Order : num 1 2 3 4 5 6 7 8 9 10 ...
$ Sample : chr "Md2" "Md3" "Md4" "Md5" ...
$ Oxoisocaproic_mean : num 0.0573 0.01 0.047 0.009 0.013 ...
$ Leu_mean : num 0.151 0.114 0.146 0.163 0.108 ...
$ Isoleu_mean : num 0.0397 0.0337 0.0383 0.0493 0.0307 ...
$ Valine_mean : num 0.143 0.1183 0.172 0.1127 0.0793 ...
$ Isobutyric_mean : num 0.0217 0.0373 0.019 0.041 0.0163 ...
$ Oxoisovaleric_mean : num 0.01933 0.00433 0.01767 0.001 0.00133 ...
$ OHbutyric_mean : num 0.0873 0.0387 0.026 0.058 0.0497 ...
$ Lactate_mean : num 0.896 0.891 1.026 0.943 1.258 ...
$ Alanine_mean : num 0.277 0.238 0.347 0.256 0.228 ...
$ Acetate_mean : num 0.125 0.334 0.342 0.36 0.402 ...
$ Glycoprot_mean : num 0.0753 0.046 0.0583 0.061 0.046 ...
$ Acetone_mean : num 0.01833 0.00767 0.01 0.012 0.00933 ...
$ Gluacid_mean : num 0.0463 0.045 0.0523 0.047 0.045 ...
$ Pyruvate_mean : num 0.01433 0.00567 0.00867 0.00767 0.00567 ...
$ Pyroglu_mean : num 0.0207 0.0407 0.016 0.0353 0.039 ...
$ Gln_mean : num 0.1757 0.0967 0.1573 0.1117 0.119 ...
$ Citrate_mean : num 0.0203 0.0157 0.0257 0.0207 0.029 ...
$ Asn_mean : num 0.00833 0.00667 0.007 0.00633 0.007 ...
$ Creatinine_mean : num 0.0443 0.0443 0.049 0.0377 0.042 ...
$ Creatine_mean : num 0.036 0.039 0.044 0.035 0.0233 ...
$ Lysine_mean : num 0.04567 0.00433 0.04367 0.005 0.005 ...
$ Ornithine_mean : num 0.02333 0.00633 0.01567 0.01033 0.00933 ...
$ Choline_mean : num 0.0303 0.0277 0.0287 0.024 0.0283 ...
$ Carnitine_mean : num 0.0607 0.102 0.0913 0.1153 0.1057 ...
$ Betaine_mean : num 0.126 0.0597 0.0657 0.0727 0.0473 ...
$ Glycine_mean : num 0.1213 0.068 0.105 0.0483 0.054 ...
$ Threonine_mean : num 0.032 0.017 0.0327 0.0107 0.015 ...
$ Glycerol_mean : num 0.03 0.003 0.03167 0.01233 0.00933 ...
$ Serine_mean : num 0.0277 0.018 0.0237 0.0283 0.028 ...
$ Proline_mean : num 0.03 0.0183 0.0263 0.0307 0.026 ...
$ BGlucose_mean : num 0.245 0.153 0.238 0.178 0.158 ...
$ DGlucose_mean : num 0.379 0.221 0.373 0.261 0.241 ...
$ Methys_mean : num 0.01733 0.00367 0.01133 0.00167 0.00333 ...
$ Tyrosine_mean : num 0.0407 0.0233 0.0327 0.03 0.021 ...
$ Phe_mean : num 0.035 0.036 0.0347 0.0307 0.0247 ...
$ Tryp_mean : num 0.015 0.015 0.017 0.0127 0.0113 ...
$ Formate_mean : num 0.00867 0.025 0.01 0.022 0.02567 ...
$ Oxoisocaproic_G0 : num 0.0518 0.0148 0.0551 0.0145 0.0224 ...
$ Oxoisocap_AUCgluc : num -0.00673 -0.00214 -0.00543 -0.0041 -0.00866 ...
$ Oxoisocaproic_L0 : num 0.051 0.01181 0.04199 0.00463 0.00948 ...
$ Oxoisocap_AUClipid : num -0.00622 0.00142 -0.0109 0.00529 0.00231 ...
$ Oxoisocaproic_P0 : num 0.06859 0.00312 0.0437 0.0084 0.00787 ...
$ Oxoisocap_AUCprot : num -0.013101 -0.000119 0.005073 -0.001926 -0.001248 ...
$ Leu_G0 : num 0.1443 0.1318 0.1516 0.1365 0.0935 ...
$ Leu_AUCgluc : num -0.0322 -0.0235 -0.0179 -0.0442 -0.0129 ...
$ Leu_L0 : num 0.173 0.107 0.114 0.187 0.102 ...
$ Leu_AUClipid : num -0.02595 -0.01064 0.00926 -0.04509 -0.02946 ...
$ Leu_P0 : num 0.136 0.103 0.172 0.165 0.128 ...
$ Leu_AUCprot : num 0.1233 0.148 0.0457 0.1309 0.1262 ...
$ Isoleu_G0 : num 0.0422 0.0336 0.0442 0.0365 0.0249 ...
$ Isoleu_AUGgluc : num -0.01406 -0.00595 -0.01167 -0.01176 -0.00623 ...
$ Isoleu_L0 : num 0.0531 0.0361 0.0324 0.0527 0.0323 ...
$ Isoleu_AUGlipid : num -0.010252 -0.006543 0.000303 -0.011161 -0.005115 ...
$ Isoleu_P0 : num 0.0235 0.0313 0.0391 0.0576 0.0349 ...
$ Isoleu_AUGprot : num 0.0576 0.0444 0.0395 0.0409 0.0469 ...
$ Valine_G0 : num 0.1507 0.1334 0.1994 0.095 0.0616 ...
$ Valine_AUGgluc : num -0.04244 -0.03201 -0.03191 -0.01836 -0.00688 ...
$ Valine_L0 : num 0.1497 0.1039 0.1303 0.1035 0.0799 ...
$ Valine_AUGlipid : num -0.0104 -0.01073 -0.00749 -0.01144 -0.01356 ...
$ Valine_P0 : num 0.1282 0.1183 0.1872 0.1393 0.0956 ...
$ Valine_AUGprot : num 0.0975 0.1103 0.0383 0.1016 0.1038 ...
$ Isobutyric_G0 : num 0.022 0.0383 0.0203 0.0474 0.0113 ...
$ Isobutyric_AUGgluc : num -0.00332 -0.00911 0.0019 -0.01931 0.00502 ...
$ Isobutyric_L0 : num 0.02273 0.02997 0.02352 0.02753 0.00446 ...
$ Isobutyric_AUGlipid : num -0.00619 -0.0079 -0.00927 -0.00333 0.01239 ...
$ Isobutyric_P0 : num 0.0195 0.0437 0.0125 0.0484 0.0344 ...
$ Isobutyric_AUGprot : num 0.00537 -0.00597 0.01362 -0.00905 0.00422 ...
$ Oxoisovaleric_G0 : num 2.03e-02 5.28e-03 2.64e-02 2.20e-06 3.37e-03 ...
$ Oxoisovaleric_AUGgluc : num 0.00112 -0.003264 -0.008018 0.00116 -0.000125 ...
$ Oxoisovaleric_L0 : num 0.01881 0.00361 0.00607 0 0.00119 ...
$ Oxoisovaleric_AUGlipid: num -0.00071 0.000624 0.001005 0.002536 0.001342 ...
$ Oxoisovaleric_P0 : num 0.01894 0.00351 0.02071 0.00302 0 ...
$ Oxoisovaleric_AUGprot : num -0.002827 -0.001562 -0.004982 0.003797 0.000605 ...
$ OHbutyric_G0 : num 0.1744 0.0543 0.0405 0.0538 0.031 ...
$ OHbutyric_AUGgluc : num -0.1183 -0.0304 -0.025 -0.0321 -0.0119 ...
$ OHbutyric_L0 : num 0.0576 0.0348 0.0204 0.0442 0.0788 ...
$ OHbutyric_AUGlipid : num 0.07737 0.00218 0.01478 0.07595 0.12219 ...
$ OHbutyric_P0 : num 0.0303 0.0268 0.017 0.0758 0.0387 ...
$ OHbutyric_AUGprot : num 0.00403 0.01189 0.00192 -0.0023 -0.0016 ...
$ Lactate_G0 : num 0.581 0.922 0.929 0.946 1.897 ...
$ Lactate_AUGgluc : num 0.634 0.323 0.265 0.3 0.12 ...
$ Lactate_L0 : num 1.003 0.781 0.973 0.902 0.912 ...
$ Lactate_AUGlipid : num -0.2895 0.112 -0.2624 -0.0699 0.0988 ...
$ Lactate_P0 : num 1.104 0.971 1.175 0.98 0.966 ...
$ Lactate_AUGprot : num -0.0553 0.081 -0.1383 0.162 0.0373 ...
$ Alanine_G0 : num 0.191 0.202 0.31 0.276 0.302 ...
$ Alanine_AUGgluc : num 0.04772 0.06301 0.00465 -0.02003 -0.00129 ...
$ Alanine_L0 : num 0.339 0.236 0.314 0.251 0.19 ...
$ Alanine_AUGlipid : num -0.0806 0.0273 -0.058 -0.0238 -0.033 ...
$ Alanine_P0 : num 0.301 0.277 0.417 0.24 0.192 ...
$ Alanine_AUGprot : num 0.091 0.0552 0.0152 0.0234 0.0786 ...
$ Acetate_G0 : num 0.101 0.335 0.334 0.366 0.402 ...
$ Acetate_AUGgluc : num 0.01028 -0.01444 -0.03058 0.00806 0.01222 ...
$ Acetate_L0 : num 0.147 0.333 0.351 0.402 0.441 ...
$ Acetate_AUGlipid : num -0.00395 -0.03058 -0.168 -0.00451 -0.054 ...
$ Acetate_P0 : num 0.128 0.335 0.342 0.313 0.363 ...
$ Acetate_AUGprot : num -0.00974 -0.01856 0.0043 0.03414 0.06576 ...
[list output truncated]Create a numerical descriptive table, with the meaning of the variables encoding.
> metabolome.variables <- metabolome[, 3:ncol(metabolome)] ## remove samples names and order from the summary
>
>
> metabolome.sum <- metabolome.variables %>%
+ group_by(GROUP, OBESE) %>%
+ summarise(across(where(is.numeric), resumen), n = n()) %>%
+ mutate_if(is.numeric, format, 4) # Group the data by variable GROUP and OBESE
>
> d.f <- as.data.frame(t(metabolome.sum))[c(nrow(t(metabolome.sum)), 1:(nrow(t(metabolome.sum)) -
+ 1)), ] # transpose the data for visualization purposes and get rid off the N value for same purposes
> d.f_final <- d.f[-c(1:3), ] # remove categorical variables.
> auxfn <- function(ch) {
+ # Function that help us to build the meaning of each variable
+
+ meas1 <- paste("Mean value (a.u)", ch)
+ return(meas1)
+
+ }
>
> auxfn2 <- function(ch) {
+ # Function that help us to build the meaning of each variable (2)
+ gb <- paste("Basal levels at glucose oral load day:", ch, "(a.u)")
+ gp <- paste("Postpradial levels at lipids oral load day:", ch, "(a.u)")
+ lb <- paste("Basal levels at glucose proteins oral load day:", ch, "(a.u)")
+ lp <- paste("Postpradial levels at glucose oral load day:", ch, "(a.u)")
+ pb <- paste("Basal levels at lipids oral load day:", ch, "(a.u)")
+ pp <- paste("Postpradial levels at porteins oral load day:", ch, "(a.u)")
+ return(c(gb, gp, lb, lp, pb, pp))
+ }
>
> # name of each variable.
> nombre_metabolitos_variable <- c(unlist(lapply(metabolites_name, auxfn)), unlist(lapply(metabolites_name,
+ auxfn2)))
>
> rownames(d.f_final) <- nombre_metabolitos_variable
> N <- as.character(d.f_final[1, ])
> colnames(d.f_final) <- rep(c("Mean", "SD"), 6)
> d.f_final$varcode <- colnames(metabolome)[3:(ncol(metabolome) - 2)]
> colnames(d.f_final)[13] <- "variable Code"
> ## ATTENION! Because assining left hand expression is complicated, just for one
> ## table, be careful if we put another data-set For showing the number of
> ## subjects by group
> as.data.frame(d.f_final) Mean
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0204
Mean value (a.u) Leucine_1 0.1216
Mean value (a.u) Isoleucine_1 0.0358
Mean value (a.u) L-Valine_1 0.1063
Mean value (a.u) Isobutyric acid_1 0.0260
Mean value (a.u) 2-oxoisovaleric acid_1 0.0067
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0547
Mean value (a.u) Lactate_1 1.0700
Mean value (a.u) Alanine_1 0.2493
Mean value (a.u) Acetate_1 0.3652
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0576
Mean value (a.u) Acetone_1 0.0105
Mean value (a.u) L-Glutamic acid_1 0.0454
Mean value (a.u) Pyruvate_1 0.0068
Mean value (a.u) Pyroglutamic acid_1 0.0350
Mean value (a.u) L-Glutamine_1 0.1226
Mean value (a.u) Citrate_2 0.0249
Mean value (a.u) L-Asparagine_4 0.0071
Mean value (a.u) Creatinine_1 0.0463
Mean value (a.u) Creatine_1 0.0292
Mean value (a.u) Lysine_1 0.0150
Mean value (a.u) Ornithine_1 0.0116
Mean value (a.u) Choline_1 0.0290
Mean value (a.u) L-Carnitine_1 0.0934
Mean value (a.u) Betaine_1 0.0810
Mean value (a.u) Glycine_1 0.0781
Mean value (a.u) L-Threonine_1 0.0202
Mean value (a.u) Glycerol_2 0.0144
Mean value (a.u) L-Serine_1 0.0266
Mean value (a.u) L-Proline_3 0.0246
Mean value (a.u) beta-Glucose_1 0.1744
Mean value (a.u) D-Glucose_2 0.2627
Mean value (a.u) 1-Methylhistidine_1 0.0053
Mean value (a.u) Tyrosine_1 0.0274
Mean value (a.u) L-Phenylalanine_2 0.0306
Mean value (a.u) L-Tryptophan_4 0.0123
Mean value (a.u) Formate_1 0.0191
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0216
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0029
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0194
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0021
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0203
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0035
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.1194
Postpradial levels at lipids oral load day: Leucine_1 (a.u) -0.0205
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.1199
Postpradial levels at glucose oral load day: Leucine_1 (a.u) -0.0082
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.1255
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.1195
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0344
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) -0.0088
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0374
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) -0.0049
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0357
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0432
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.1095
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) -0.0220
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0957
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) -0.0073
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.1136
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0898
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0285
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) -0.0057
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.021
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) -0.0023
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0282
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0069
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0077
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0013
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0041
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0011
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0084
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0015
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0578
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0336
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0454
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0756
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0608
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0122
Basal levels at glucose oral load day: Lactate_1 (a.u) 1.1376
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2059
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 1.1333
Postpradial levels at glucose oral load day: Lactate_1 (a.u) -0.2396
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.9390
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.1209
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.2441
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0119
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.2497
Postpradial levels at glucose oral load day: Alanine_1 (a.u) -0.0324
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.2541
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0548
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.3778
Postpradial levels at lipids oral load day: Acetate_1 (a.u) -0.0108
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.3548
Postpradial levels at glucose oral load day: Acetate_1 (a.u) -0.0151
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.3629
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0148
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0562
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0023
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0583
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0053
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0584
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0027
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0115
Postpradial levels at lipids oral load day: Acetone_1 (a.u) -0.0012
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0103
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0004
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0096
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 8e-04
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0486
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) -0.0034
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0428
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) -0.0032
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0447
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0172
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0061
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0033
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0065
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) -0.0008
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0076
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0064
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0348
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) -0.0048
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0354
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0117
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0351
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) -0.0001
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.1220
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) -0.0012
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.1207
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0017
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.1253
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0149
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0257
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0047
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0247
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0037
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0242
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0008
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0070
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0e+00
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0072
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0002
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 7e-03
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0023
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0467
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) -0.0033
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0445
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) -0.0018
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0476
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) -0.0014
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0311
Postpradial levels at lipids oral load day: Creatine_1 (a.u) -0.0025
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0265
Postpradial levels at glucose oral load day: Creatine_1 (a.u) -0.0046
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0298
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0090
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0170
Postpradial levels at lipids oral load day: Lysine_1 (a.u) -0.0014
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0135
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0019
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0146
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0185
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0112
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) -0.0012
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0124
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) -0.0004
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0111
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0010
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0316
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0000
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0286
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0019
Basal levels at lipids oral load day: Choline_1 (a.u) 0.027
Postpradial levels at porteins oral load day: Choline_1 (a.u) 0.0019
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0962
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) -0.0039
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0881
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) -0.0057
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0960
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) -0.0022
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0870
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0017
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0796
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0007
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0767
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0064
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0738
Postpradial levels at lipids oral load day: Glycine_1 (a.u) -0.0069
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0786
Postpradial levels at glucose oral load day: Glycine_1 (a.u) -0.0082
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0819
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0015
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0206
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) -0.0045
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0187
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) -0.0031
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0216
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0110
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0134
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) -0.0042
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0154
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) -0.0003
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0142
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) -0.0047
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0281
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) -0.0030
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0269
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0009
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0249
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0138
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0245
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) -0.0028
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0232
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0053
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0260
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0093
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.1843
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0563
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.1638
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) -0.0072
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.1751
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) -0.0126
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.2767
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0785
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.2590
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) -0.0157
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.2523
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) -0.0135
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0050
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) -1e-04
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0056
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) -0.0013
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0052
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.001
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0266
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) -0.0038
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0288
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) -0.0046
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0271
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.019
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0306
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) -0.0028
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0300
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) -0.0033
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0310
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0083
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0113
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) -5e-04
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0135
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) -0.0013
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0123
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0021
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0195
Postpradial levels at lipids oral load day: Formate_1 (a.u) -0.0016
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0183
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0000
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0195
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0023
SD
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0183
Mean value (a.u) Leucine_1 0.0250
Mean value (a.u) Isoleucine_1 0.0065
Mean value (a.u) L-Valine_1 0.0332
Mean value (a.u) Isobutyric acid_1 0.0087
Mean value (a.u) 2-oxoisovaleric acid_1 0.0071
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0263
Mean value (a.u) Lactate_1 0.2641
Mean value (a.u) Alanine_1 0.0477
Mean value (a.u) Acetate_1 0.0997
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0111
Mean value (a.u) Acetone_1 0.0032
Mean value (a.u) L-Glutamic acid_1 0.0035
Mean value (a.u) Pyruvate_1 0.0032
Mean value (a.u) Pyroglutamic acid_1 0.0103
Mean value (a.u) L-Glutamine_1 0.0266
Mean value (a.u) Citrate_2 0.0053
Mean value (a.u) L-Asparagine_4 0.0006
Mean value (a.u) Creatinine_1 0.0062
Mean value (a.u) Creatine_1 0.0106
Mean value (a.u) Lysine_1 0.0171
Mean value (a.u) Ornithine_1 0.0053
Mean value (a.u) Choline_1 0.0049
Mean value (a.u) L-Carnitine_1 0.0183
Mean value (a.u) Betaine_1 0.0265
Mean value (a.u) Glycine_1 0.0236
Mean value (a.u) L-Threonine_1 0.0074
Mean value (a.u) Glycerol_2 0.0097
Mean value (a.u) L-Serine_1 0.0046
Mean value (a.u) L-Proline_3 0.0041
Mean value (a.u) beta-Glucose_1 0.0393
Mean value (a.u) D-Glucose_2 0.0663
Mean value (a.u) 1-Methylhistidine_1 0.0054
Mean value (a.u) Tyrosine_1 0.0062
Mean value (a.u) L-Phenylalanine_2 0.0039
Mean value (a.u) L-Tryptophan_4 0.0028
Mean value (a.u) Formate_1 0.0060
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0188
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0036
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0160
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0052
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0216
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0058
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.0220
Postpradial levels at lipids oral load day: Leucine_1 (a.u) 0.0124
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.0378
Postpradial levels at glucose oral load day: Leucine_1 (a.u) 0.0220
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.0281
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0381
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0071
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) 0.0037
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0095
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) 0.0046
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0096
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0097
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.0438
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) 0.0117
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0300
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) 0.0049
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.0351
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0261
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0134
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0097
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.008
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0069
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0143
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0117
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0093
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0033
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0059
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0010
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0080
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0034
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0448
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0329
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0205
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0693
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0543
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0314
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.4693
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2705
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.6387
Postpradial levels at glucose oral load day: Lactate_1 (a.u) 0.4802
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.1639
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.2340
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.0478
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0278
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.0529
Postpradial levels at glucose oral load day: Alanine_1 (a.u) 0.0317
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.0805
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0322
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.1204
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0240
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.0936
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0747
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.1047
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0267
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0111
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0119
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0062
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0109
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0037
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0087
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0046
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0020
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0051
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0032
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 3e-03
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0061
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0057
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0043
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0038
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0064
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0072
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0023
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0092
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0043
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) 0.0029
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0055
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0028
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0094
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0065
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0090
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0144
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0157
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) 0.0053
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0249
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0159
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.0283
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0097
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0339
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0114
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0062
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0056
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0079
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0051
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0056
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0041
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0013
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 9e-04
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0021
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0022
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 9e-04
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0013
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0062
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0046
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0072
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) 0.0071
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0102
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0053
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0131
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0050
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0120
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0061
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0112
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0079
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0199
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.0045
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0161
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0058
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0168
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0131
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0074
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0040
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0043
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 0.0038
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0053
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0043
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0060
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0039
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0102
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0088
Basal levels at lipids oral load day: Choline_1 (a.u) 0.011
Postpradial levels at porteins oral load day: Choline_1 (a.u) 0.0078
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0228
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0098
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0220
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0168
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0253
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0179
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0289
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0089
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0283
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0139
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0323
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0128
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0203
Postpradial levels at lipids oral load day: Glycine_1 (a.u) 0.0081
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0261
Postpradial levels at glucose oral load day: Glycine_1 (a.u) 0.0089
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0301
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0040
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0110
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) 0.0077
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0093
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0051
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0093
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0075
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0146
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) 0.0091
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0120
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0084
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0086
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) 0.0071
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0042
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) 0.0054
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0062
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0031
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0083
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0087
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0066
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) 0.0038
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0071
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0070
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0053
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0063
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0431
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0646
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.0412
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0140
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0427
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0169
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.0732
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0869
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.0797
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) 0.0270
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.0499
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0196
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0048
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 5e-04
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0067
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0021
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0050
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.002
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0063
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) 0.0038
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0106
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) 0.0052
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0047
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.007
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0057
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0026
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0045
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0033
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0044
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0042
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0029
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 2e-03
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0040
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0025
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0029
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0026
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0066
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0018
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0061
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0033
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0071
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0019
Mean
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0428
Mean value (a.u) Leucine_1 0.1338
Mean value (a.u) Isoleucine_1 0.0402
Mean value (a.u) L-Valine_1 0.1409
Mean value (a.u) Isobutyric acid_1 0.0175
Mean value (a.u) 2-oxoisovaleric acid_1 0.0169
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0488
Mean value (a.u) Lactate_1 1.1345
Mean value (a.u) Alanine_1 0.2649
Mean value (a.u) Acetate_1 0.0620
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0412
Mean value (a.u) Acetone_1 0.023
Mean value (a.u) L-Glutamic acid_1 0.0436
Mean value (a.u) Pyruvate_1 0.0209
Mean value (a.u) Pyroglutamic acid_1 0.0157
Mean value (a.u) L-Glutamine_1 0.1330
Mean value (a.u) Citrate_2 0.0202
Mean value (a.u) L-Asparagine_4 0.0063
Mean value (a.u) Creatinine_1 0.0399
Mean value (a.u) Creatine_1 0.0325
Mean value (a.u) Lysine_1 0.0523
Mean value (a.u) Ornithine_1 0.0193
Mean value (a.u) Choline_1 0.0264
Mean value (a.u) L-Carnitine_1 0.0615
Mean value (a.u) Betaine_1 0.0570
Mean value (a.u) Glycine_1 0.0836
Mean value (a.u) L-Threonine_1 0.0234
Mean value (a.u) Glycerol_2 0.0272
Mean value (a.u) L-Serine_1 0.0238
Mean value (a.u) L-Proline_3 0.0226
Mean value (a.u) beta-Glucose_1 0.2288
Mean value (a.u) D-Glucose_2 0.3342
Mean value (a.u) 1-Methylhistidine_1 0.0135
Mean value (a.u) Tyrosine_1 0.0325
Mean value (a.u) L-Phenylalanine_2 0.0293
Mean value (a.u) L-Tryptophan_4 0.0155
Mean value (a.u) Formate_1 0.0124
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0418
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0027
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0449
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0044
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.042
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0136
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.1422
Postpradial levels at lipids oral load day: Leucine_1 (a.u) -0.0305
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.1305
Postpradial levels at glucose oral load day: Leucine_1 (a.u) -0.0076
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.1289
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.1554
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0406
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) -0.0124
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0407
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) -0.0055
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0391
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0562
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.1424
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) -0.0212
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.1406
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) -0.0066
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.1398
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.1155
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0179
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) -0.0015
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0162
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) -0.0007
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0183
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0063
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0162
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0006
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0172
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0003
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0171
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0001
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0444
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0215
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0437
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0574
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0583
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0159
Basal levels at glucose oral load day: Lactate_1 (a.u) 1.1283
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2565
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 1.0738
Postpradial levels at glucose oral load day: Lactate_1 (a.u) -0.1407
Basal levels at lipids oral load day: Lactate_1 (a.u) 1.2016
Postpradial levels at porteins oral load day: Lactate_1 (a.u) -0.0425
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.2727
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0052
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.2551
Postpradial levels at glucose oral load day: Alanine_1 (a.u) -0.0165
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.2670
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0833
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.0553
Postpradial levels at lipids oral load day: Acetate_1 (a.u) -0.0058
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.0606
Postpradial levels at glucose oral load day: Acetate_1 (a.u) -0.0025
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.0700
Postpradial levels at porteins oral load day: Acetate_1 (a.u) -0.018
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0385
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0009
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0413
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0004
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0437
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0021
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0274
Postpradial levels at lipids oral load day: Acetone_1 (a.u) -0.0051
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0199
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0043
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0216
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0016
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0477
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) -0.0052
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0410
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) -0.0013
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.042
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0189
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0250
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0068
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0182
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) -0.0008
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0196
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0099
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0139
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) -0.0046
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0141
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0089
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0191
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) -0.0061
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.128
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) -0.0095
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.1277
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0102
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.1431
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0159
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0195
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0004
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0189
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0035
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0224
Postpradial levels at porteins oral load day: Citrate_2 (a.u) -0.0014
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0059
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) -0.0002
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0072
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) -0.0008
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0056
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0034
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0385
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) -0.0018
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0425
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) -0.0019
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0390
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0021
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0345
Postpradial levels at lipids oral load day: Creatine_1 (a.u) -0.0014
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0306
Postpradial levels at glucose oral load day: Creatine_1 (a.u) -0.0015
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0321
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0147
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0545
Postpradial levels at lipids oral load day: Lysine_1 (a.u) -0.0107
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0529
Postpradial levels at glucose oral load day: Lysine_1 (a.u) -0.0025
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0493
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0466
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0186
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) -0.0017
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0200
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) -0.0008
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0194
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0042
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0241
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0001
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0258
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0024
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0297
Postpradial levels at porteins oral load day: Choline_1 (a.u) -0.0028
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0582
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) -0.0001
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0622
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.006
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0641
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0025
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0573
Postpradial levels at lipids oral load day: Betaine_1 (a.u) -0.0021
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0585
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0030
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0553
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0121
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0831
Postpradial levels at lipids oral load day: Glycine_1 (a.u) -0.0070
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0821
Postpradial levels at glucose oral load day: Glycine_1 (a.u) -0.0020
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0859
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0029
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0238
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) -0.0024
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0238
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) -0.0014
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0225
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0139
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0233
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) -0.0069
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0280
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) -0.0008
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0303
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) -0.0083
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0213
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) -0.0023
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0232
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) -0.0006
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0271
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0084
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0224
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) -0.0017
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0217
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0051
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0237
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0106
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.2370
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0836
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.2162
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) -0.0026
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.2334
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0002
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.3368
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.1128
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.3243
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) -0.0039
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.342
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0023
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0132
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) -0.0014
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0139
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) -0.0010
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0132
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0041
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0339
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) -0.0063
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0299
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) -0.0010
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0336
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0289
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0291
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) -0.0029
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0283
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) -0.0016
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0304
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0113
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0136
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) -0.0005
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0164
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) -0.0029
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0160
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0020
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0124
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0006
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0130
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0001
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0118
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0016
SD
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0101
Mean value (a.u) Leucine_1 0.0349
Mean value (a.u) Isoleucine_1 0.0121
Mean value (a.u) L-Valine_1 0.0350
Mean value (a.u) Isobutyric acid_1 0.0043
Mean value (a.u) 2-oxoisovaleric acid_1 0.0043
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0212
Mean value (a.u) Lactate_1 0.4346
Mean value (a.u) Alanine_1 0.0575
Mean value (a.u) Acetate_1 0.0364
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0082
Mean value (a.u) Acetone_1 0.003
Mean value (a.u) L-Glutamic acid_1 0.0167
Mean value (a.u) Pyruvate_1 0.0106
Mean value (a.u) Pyroglutamic acid_1 0.0036
Mean value (a.u) L-Glutamine_1 0.0252
Mean value (a.u) Citrate_2 0.0070
Mean value (a.u) L-Asparagine_4 0.0016
Mean value (a.u) Creatinine_1 0.0073
Mean value (a.u) Creatine_1 0.0107
Mean value (a.u) Lysine_1 0.0131
Mean value (a.u) Ornithine_1 0.0043
Mean value (a.u) Choline_1 0.0062
Mean value (a.u) L-Carnitine_1 0.0107
Mean value (a.u) Betaine_1 0.0129
Mean value (a.u) Glycine_1 0.0226
Mean value (a.u) L-Threonine_1 0.0107
Mean value (a.u) Glycerol_2 0.0070
Mean value (a.u) L-Serine_1 0.0080
Mean value (a.u) L-Proline_3 0.0102
Mean value (a.u) beta-Glucose_1 0.0399
Mean value (a.u) D-Glucose_2 0.0608
Mean value (a.u) 1-Methylhistidine_1 0.0032
Mean value (a.u) Tyrosine_1 0.0088
Mean value (a.u) L-Phenylalanine_2 0.0058
Mean value (a.u) L-Tryptophan_4 0.0025
Mean value (a.u) Formate_1 0.0018
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0100
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0064
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0139
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0105
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.012
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0129
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.0606
Postpradial levels at lipids oral load day: Leucine_1 (a.u) 0.0217
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.0271
Postpradial levels at glucose oral load day: Leucine_1 (a.u) 0.0157
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.0299
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0428
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0228
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) 0.0086
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0116
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) 0.0082
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0077
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0121
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.0484
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) 0.0132
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0347
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) 0.0130
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.0330
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0259
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0058
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0043
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0049
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0046
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0031
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0042
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0051
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0031
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0051
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0035
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0045
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0024
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0208
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0116
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0294
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0402
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0333
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0147
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.4463
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2802
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.6222
Postpradial levels at glucose oral load day: Lactate_1 (a.u) 0.3260
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.4422
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.2126
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.0672
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0315
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.0636
Postpradial levels at glucose oral load day: Alanine_1 (a.u) 0.0203
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.0713
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0473
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.0344
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0073
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.0429
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0044
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.0342
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.006
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0088
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0037
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0070
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0064
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0106
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0019
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0053
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0027
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0016
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0044
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0054
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0032
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0196
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0044
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0147
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0034
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.017
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0056
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0129
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0076
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0107
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) 0.0075
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0125
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0063
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0042
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0024
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0061
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0092
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0080
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) 0.0060
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.019
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0093
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.0201
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0097
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0398
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0170
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0080
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0044
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0055
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0044
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0086
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0037
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0017
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0011
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0022
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0015
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0022
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0009
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0066
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0066
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0085
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) 0.0037
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0096
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0059
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0172
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0073
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0091
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0035
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0082
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0088
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0161
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.0066
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0129
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0053
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0168
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0141
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0052
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0038
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0047
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 0.0028
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0064
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0043
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0069
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0048
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0094
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0065
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0090
Postpradial levels at porteins oral load day: Choline_1 (a.u) 0.0102
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0117
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0087
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0128
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.005
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0137
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0061
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0096
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0113
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0144
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0067
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0203
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0185
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0186
Postpradial levels at lipids oral load day: Glycine_1 (a.u) 0.0068
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0245
Postpradial levels at glucose oral load day: Glycine_1 (a.u) 0.0096
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0303
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0066
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0159
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) 0.0039
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0109
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0064
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0083
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0068
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0055
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) 0.0051
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0135
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0072
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0115
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) 0.0079
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0032
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0076
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0064
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0187
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0092
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0134
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) 0.0038
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0108
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0047
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0082
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0035
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0432
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0555
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.0451
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0172
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0394
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0153
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.0713
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0717
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.0587
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) 0.0394
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.062
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0234
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0030
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0018
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0036
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0025
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0042
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0011
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0121
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0078
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) 0.0076
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0105
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0085
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0053
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0028
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0058
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0032
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0071
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0027
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0032
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0018
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0025
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0007
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0037
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0024
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0021
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0019
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0024
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0021
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0025
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0015
Mean
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0358
Mean value (a.u) Leucine_1 0.1377
Mean value (a.u) Isoleucine_1 0.0336
Mean value (a.u) L-Valine_1 0.1234
Mean value (a.u) Isobutyric acid_1 0.0224
Mean value (a.u) 2-oxoisovaleric acid_1 0.0121
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0414
Mean value (a.u) Lactate_1 0.9779
Mean value (a.u) Alanine_1 0.2931
Mean value (a.u) Acetate_1 0.3065
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0554
Mean value (a.u) Acetone_1 0.0117
Mean value (a.u) L-Glutamic acid_1 0.0453
Mean value (a.u) Pyruvate_1 0.0125
Mean value (a.u) Pyroglutamic acid_1 0.0230
Mean value (a.u) L-Glutamine_1 0.1514
Mean value (a.u) Citrate_2 0.0252
Mean value (a.u) L-Asparagine_4 0.0081
Mean value (a.u) Creatinine_1 0.0460
Mean value (a.u) Creatine_1 0.0236
Mean value (a.u) Lysine_1 0.0300
Mean value (a.u) Ornithine_1 0.0158
Mean value (a.u) Choline_1 0.0306
Mean value (a.u) L-Carnitine_1 0.0780
Mean value (a.u) Betaine_1 0.0830
Mean value (a.u) Glycine_1 0.1061
Mean value (a.u) L-Threonine_1 0.0239
Mean value (a.u) Glycerol_2 0.0217
Mean value (a.u) L-Serine_1 0.0293
Mean value (a.u) L-Proline_3 0.0233
Mean value (a.u) beta-Glucose_1 0.2202
Mean value (a.u) D-Glucose_2 0.3166
Mean value (a.u) 1-Methylhistidine_1 0.0099
Mean value (a.u) Tyrosine_1 0.0317
Mean value (a.u) L-Phenylalanine_2 0.0322
Mean value (a.u) L-Tryptophan_4 0.0147
Mean value (a.u) Formate_1 0.0104
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0345
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0024
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0368
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0053
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0360
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0004
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.1420
Postpradial levels at lipids oral load day: Leucine_1 (a.u) -0.0311
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.1358
Postpradial levels at glucose oral load day: Leucine_1 (a.u) -0.0107
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.1354
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0993
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0330
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) -0.0073
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0310
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) -0.0005
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0367
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0381
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.1286
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) -0.0190
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.1199
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) -0.0086
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.1215
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0693
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0240
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) -0.0012
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0207
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) -0.0041
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0227
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0067
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0115
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0006
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0126
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0026
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0121
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0025
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0494
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0241
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0292
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0768
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0455
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0035
Basal levels at glucose oral load day: Lactate_1 (a.u) 1.0027
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2856
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.9956
Postpradial levels at glucose oral load day: Lactate_1 (a.u) -0.0544
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.9355
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.0115
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.2682
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.3088
Postpradial levels at glucose oral load day: Alanine_1 (a.u) -0.0365
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.3022
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0427
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.2869
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0162
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.3107
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0017
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.3219
Postpradial levels at porteins oral load day: Acetate_1 (a.u) -0.0242
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0541
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0006
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0552
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0025
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0567
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0056
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0122
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0002
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0124
Postpradial levels at glucose oral load day: Acetone_1 (a.u) -0.0016
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0108
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0013
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0461
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) -0.0034
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0439
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) -0.0046
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0456
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0105
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0118
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0011
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0135
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) -0.0028
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0121
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0027
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0241
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) -0.0042
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0199
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0129
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0250
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) -0.0012
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.1526
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) -0.0057
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.1482
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0044
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.1535
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0171
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0249
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0041
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0249
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0057
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0258
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0006
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0078
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) -0.0009
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0085
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) -2e-04
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0080
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.002
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0427
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0028
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0468
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) -0.0040
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0484
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) -0.0035
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0210
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0029
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0222
Postpradial levels at glucose oral load day: Creatine_1 (a.u) -0.0018
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0278
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0072
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0330
Postpradial levels at lipids oral load day: Lysine_1 (a.u) -0.0064
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0308
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0005
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0263
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0270
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0176
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) -0.0016
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0145
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 6e-04
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0156
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0019
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0313
Postpradial levels at lipids oral load day: Choline_1 (a.u) -0.0009
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0290
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0025
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0316
Postpradial levels at porteins oral load day: Choline_1 (a.u) 4e-04
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0772
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0064
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0711
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0074
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0853
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) -0.0081
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0753
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0024
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0849
Postpradial levels at glucose oral load day: Betaine_1 (a.u) -0.0083
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0887
Postpradial levels at porteins oral load day: Betaine_1 (a.u) -0.0039
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.1045
Postpradial levels at lipids oral load day: Glycine_1 (a.u) -0.0036
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.1039
Postpradial levels at glucose oral load day: Glycine_1 (a.u) -0.0007
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.1099
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0028
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0253
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) -0.0030
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0245
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) -0.0024
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0220
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0127
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0238
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) -0.0074
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0219
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) -0.0013
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0197
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) -0.0052
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0326
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) -0.0060
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0256
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) -0.0008
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0297
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0057
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0252
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) -0.0052
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0206
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0063
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0241
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0082
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.2215
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0331
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.2143
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) -0.0125
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.225
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) -0.0234
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.3221
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0439
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.3062
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) -0.0152
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.3216
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) -0.0213
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0102
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) -0.0011
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0090
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0008
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0107
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0007
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0319
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) -0.0052
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0330
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) -0.0053
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0301
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0149
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0339
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) -0.0051
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0316
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) -0.0023
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0309
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0090
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0139
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) -0.0007
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0151
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) -0.0028
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0152
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0014
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0108
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0000
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0102
Postpradial levels at glucose oral load day: Formate_1 (a.u) -0.0001
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0102
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0011
SD
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0144
Mean value (a.u) Leucine_1 0.0200
Mean value (a.u) Isoleucine_1 0.0048
Mean value (a.u) L-Valine_1 0.0315
Mean value (a.u) Isobutyric acid_1 0.0070
Mean value (a.u) 2-oxoisovaleric acid_1 0.0067
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0206
Mean value (a.u) Lactate_1 0.1789
Mean value (a.u) Alanine_1 0.0507
Mean value (a.u) Acetate_1 0.0976
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0062
Mean value (a.u) Acetone_1 0.0023
Mean value (a.u) L-Glutamic acid_1 0.0087
Mean value (a.u) Pyruvate_1 0.0057
Mean value (a.u) Pyroglutamic acid_1 0.0149
Mean value (a.u) L-Glutamine_1 0.0143
Mean value (a.u) Citrate_2 0.0048
Mean value (a.u) L-Asparagine_4 0.0016
Mean value (a.u) Creatinine_1 0.0082
Mean value (a.u) Creatine_1 0.0113
Mean value (a.u) Lysine_1 0.0151
Mean value (a.u) Ornithine_1 0.0060
Mean value (a.u) Choline_1 0.0090
Mean value (a.u) L-Carnitine_1 0.0206
Mean value (a.u) Betaine_1 0.0247
Mean value (a.u) Glycine_1 0.0195
Mean value (a.u) L-Threonine_1 0.0094
Mean value (a.u) Glycerol_2 0.0083
Mean value (a.u) L-Serine_1 0.0040
Mean value (a.u) L-Proline_3 0.0055
Mean value (a.u) beta-Glucose_1 0.0442
Mean value (a.u) D-Glucose_2 0.0606
Mean value (a.u) 1-Methylhistidine_1 0.0055
Mean value (a.u) Tyrosine_1 0.0067
Mean value (a.u) L-Phenylalanine_2 0.0043
Mean value (a.u) L-Tryptophan_4 0.0026
Mean value (a.u) Formate_1 0.0051
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0125
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0067
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0194
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0080
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0136
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0066
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.0273
Postpradial levels at lipids oral load day: Leucine_1 (a.u) 0.0111
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.0234
Postpradial levels at glucose oral load day: Leucine_1 (a.u) 0.0132
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.0266
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0618
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0093
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) 0.0044
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0068
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) 0.0049
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0084
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0176
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.0349
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) 0.0153
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0359
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) 0.0078
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.0332
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0282
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0104
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0052
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0092
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0089
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0080
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0110
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0066
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0035
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0082
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0053
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0074
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0041
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0239
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0172
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0118
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0661
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0414
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0257
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.3110
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.1823
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.2010
Postpradial levels at glucose oral load day: Lactate_1 (a.u) 0.2198
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.3125
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.2083
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.0589
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0258
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.0678
Postpradial levels at glucose oral load day: Alanine_1 (a.u) 0.0450
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.0591
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0510
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.0604
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0408
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.1150
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0286
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.1326
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0568
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0083
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0048
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0048
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0021
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0095
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0056
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0029
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0015
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0020
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0026
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0029
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0029
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0083
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0040
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0115
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0052
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0088
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0057
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0060
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0042
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0068
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) 0.0038
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0062
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0040
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0161
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0066
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0094
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0119
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0192
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) 0.0043
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0196
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0106
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.0208
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0129
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0171
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0172
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0076
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0029
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0064
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0067
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0069
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0044
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0017
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0015
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0025
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 2e-03
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0027
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.003
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0103
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0039
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0103
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) 0.0046
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0128
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0101
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0115
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0054
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0104
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0035
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0147
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0056
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0149
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.0062
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0176
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0062
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0176
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0126
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0058
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0028
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0088
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 5e-03
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0076
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0043
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0129
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0064
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0095
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0084
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0110
Postpradial levels at porteins oral load day: Choline_1 (a.u) 6e-03
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0282
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0135
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0229
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0168
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0321
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0208
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0291
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0140
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0355
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0131
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0285
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0084
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0246
Postpradial levels at lipids oral load day: Glycine_1 (a.u) 0.0032
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0253
Postpradial levels at glucose oral load day: Glycine_1 (a.u) 0.0174
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0175
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0116
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0123
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) 0.0062
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0128
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0047
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0116
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0092
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0134
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) 0.0063
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0073
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0046
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0110
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) 0.0082
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0086
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) 0.0075
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0069
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0083
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0096
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0091
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0053
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) 0.0035
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0069
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0067
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0086
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0062
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0490
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0710
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.0553
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0208
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.045
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0272
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.0794
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0588
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.0690
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) 0.0533
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.0571
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0384
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0056
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0013
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0058
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0027
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0068
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0026
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0086
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) 0.0062
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0088
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) 0.0043
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0074
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0117
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0064
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0040
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0066
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0049
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0043
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0062
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0034
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0025
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0030
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0018
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0032
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0026
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0060
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0017
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0045
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0015
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0051
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0015
Mean
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0593
Mean value (a.u) Leucine_1 0.1703
Mean value (a.u) Isoleucine_1 0.0555
Mean value (a.u) L-Valine_1 0.1915
Mean value (a.u) Isobutyric acid_1 0.0192
Mean value (a.u) 2-oxoisovaleric acid_1 0.0240
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0601
Mean value (a.u) Lactate_1 1.3403
Mean value (a.u) Alanine_1 0.3525
Mean value (a.u) Acetate_1 0.1531
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0645
Mean value (a.u) Acetone_1 0.0307
Mean value (a.u) L-Glutamic acid_1 0.0506
Mean value (a.u) Pyruvate_1 0.0305
Mean value (a.u) Pyroglutamic acid_1 0.0148
Mean value (a.u) L-Glutamine_1 0.1683
Mean value (a.u) Citrate_2 0.0267
Mean value (a.u) L-Asparagine_4 0.0073
Mean value (a.u) Creatinine_1 0.0659
Mean value (a.u) Creatine_1 0.0386
Mean value (a.u) Lysine_1 0.0619
Mean value (a.u) Ornithine_1 0.0232
Mean value (a.u) Choline_1 0.0317
Mean value (a.u) L-Carnitine_1 0.0846
Mean value (a.u) Betaine_1 0.0676
Mean value (a.u) Glycine_1 0.0936
Mean value (a.u) L-Threonine_1 0.0302
Mean value (a.u) Glycerol_2 0.0302
Mean value (a.u) L-Serine_1 0.0231
Mean value (a.u) L-Proline_3 0.0280
Mean value (a.u) beta-Glucose_1 0.2874
Mean value (a.u) D-Glucose_2 0.4178
Mean value (a.u) 1-Methylhistidine_1 0.0159
Mean value (a.u) Tyrosine_1 0.0402
Mean value (a.u) L-Phenylalanine_2 0.0359
Mean value (a.u) L-Tryptophan_4 0.0158
Mean value (a.u) Formate_1 0.0163
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0555
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0070
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0596
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0036
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0629
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0068
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.1569
Postpradial levels at lipids oral load day: Leucine_1 (a.u) -0.0191
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.1776
Postpradial levels at glucose oral load day: Leucine_1 (a.u) -0.0062
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.1766
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.1415
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0520
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) -0.0094
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0542
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) -0.0021
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0603
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0471
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.1893
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) -0.0213
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.1927
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) -0.0044
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.1927
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0999
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0185
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) -0.0015
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0195
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) -0.0044
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0195
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0064
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0219
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0014
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0258
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0009
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0243
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0011
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0459
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0167
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0669
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0616
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0675
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0148
Basal levels at glucose oral load day: Lactate_1 (a.u) 1.2590
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2964
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 1.4677
Postpradial levels at glucose oral load day: Lactate_1 (a.u) -0.2554
Basal levels at lipids oral load day: Lactate_1 (a.u) 1.2942
Postpradial levels at porteins oral load day: Lactate_1 (a.u) -0.0511
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.3430
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0076
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.3528
Postpradial levels at glucose oral load day: Alanine_1 (a.u) -0.0158
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.3618
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0555
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.1499
Postpradial levels at lipids oral load day: Acetate_1 (a.u) -0.0052
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.1519
Postpradial levels at glucose oral load day: Acetate_1 (a.u) -0.0031
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.1575
Postpradial levels at porteins oral load day: Acetate_1 (a.u) -0.0187
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0603
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0045
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0660
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0013
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0676
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0026
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0275
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0001
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0334
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0042
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0315
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0017
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0446
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0006
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0551
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) -0.0069
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0521
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.016
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0249
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0162
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0367
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) -0.0045
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0298
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0080
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0128
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) -0.0027
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0150
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0108
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0166
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) -0.0040
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.1617
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0019
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.1704
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0093
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.1728
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0162
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0265
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0022
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0262
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0064
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0276
Postpradial levels at porteins oral load day: Citrate_2 (a.u) -2e-04
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0064
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0007
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0074
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0003
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0080
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0027
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0735
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) -0.0158
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0523
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) -0.0019
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0719
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) -0.0173
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0362
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0394
Postpradial levels at glucose oral load day: Creatine_1 (a.u) -0.0044
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0403
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0137
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.060
Postpradial levels at lipids oral load day: Lysine_1 (a.u) -0.001
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0656
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0029
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0600
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0483
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0216
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) -0.0007
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0239
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) -3e-04
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0240
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.002
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0282
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0062
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0321
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0023
Basal levels at lipids oral load day: Choline_1 (a.u) 0.035
Postpradial levels at porteins oral load day: Choline_1 (a.u) -0.0011
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0813
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0055
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0823
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0034
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0900
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0038
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0662
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0043
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0711
Postpradial levels at glucose oral load day: Betaine_1 (a.u) -0.0018
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0653
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0001
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0921
Postpradial levels at lipids oral load day: Glycine_1 (a.u) -0.0021
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0928
Postpradial levels at glucose oral load day: Glycine_1 (a.u) -0.0051
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0958
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0042
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0292
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) -0.0031
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0300
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) -0.0012
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0316
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0114
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0313
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) -0.0103
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0291
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0006
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0305
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) -0.0043
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0225
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) -0.0004
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0214
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0032
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0250
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0061
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0264
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) -0.0041
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0299
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0038
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0279
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0106
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.2697
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.1724
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.2961
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) -0.0199
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.2962
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0035
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.4084
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.2101
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.4311
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) -0.0108
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.4141
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0266
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0160
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) -0.0002
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0165
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) -0.0001
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0150
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0053
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0388
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) -0.0040
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0399
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) -0.0041
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0419
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0207
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0347
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) -0.0001
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0367
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) -0.0019
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0363
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0124
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0156
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0000
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0164
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) -0.0015
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0155
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0036
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0162
Postpradial levels at lipids oral load day: Formate_1 (a.u) -0.0004
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0161
Postpradial levels at glucose oral load day: Formate_1 (a.u) -6e-04
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0168
Postpradial levels at porteins oral load day: Formate_1 (a.u) -0.0018
SD
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0087
Mean value (a.u) Leucine_1 0.0141
Mean value (a.u) Isoleucine_1 0.0052
Mean value (a.u) L-Valine_1 0.0136
Mean value (a.u) Isobutyric acid_1 0.0044
Mean value (a.u) 2-oxoisovaleric acid_1 0.0028
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0204
Mean value (a.u) Lactate_1 0.4347
Mean value (a.u) Alanine_1 0.0545
Mean value (a.u) Acetate_1 0.0158
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0151
Mean value (a.u) Acetone_1 0.0053
Mean value (a.u) L-Glutamic acid_1 0.0062
Mean value (a.u) Pyruvate_1 0.0156
Mean value (a.u) Pyroglutamic acid_1 0.0043
Mean value (a.u) L-Glutamine_1 0.0136
Mean value (a.u) Citrate_2 0.0046
Mean value (a.u) L-Asparagine_4 0.0014
Mean value (a.u) Creatinine_1 0.0281
Mean value (a.u) Creatine_1 0.0072
Mean value (a.u) Lysine_1 0.0085
Mean value (a.u) Ornithine_1 0.0030
Mean value (a.u) Choline_1 0.0042
Mean value (a.u) L-Carnitine_1 0.0108
Mean value (a.u) Betaine_1 0.0193
Mean value (a.u) Glycine_1 0.0190
Mean value (a.u) L-Threonine_1 0.0051
Mean value (a.u) Glycerol_2 0.0076
Mean value (a.u) L-Serine_1 0.0059
Mean value (a.u) L-Proline_3 0.0026
Mean value (a.u) beta-Glucose_1 0.0186
Mean value (a.u) D-Glucose_2 0.0290
Mean value (a.u) 1-Methylhistidine_1 0.0027
Mean value (a.u) Tyrosine_1 0.0058
Mean value (a.u) L-Phenylalanine_2 0.0021
Mean value (a.u) L-Tryptophan_4 0.0021
Mean value (a.u) Formate_1 0.0023
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0131
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0113
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0104
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0093
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0109
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0153
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.0177
Postpradial levels at lipids oral load day: Leucine_1 (a.u) 0.0190
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.0162
Postpradial levels at glucose oral load day: Leucine_1 (a.u) 0.0058
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.0260
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0573
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0074
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) 0.0096
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0100
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) 0.0067
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0081
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0261
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.0304
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) 0.0219
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0213
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) 0.0109
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.0232
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0452
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0088
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0032
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0066
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0042
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0048
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0069
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0042
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0037
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0046
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0035
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0058
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0058
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0181
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0128
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0510
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0466
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0194
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0133
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.4811
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2377
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.6231
Postpradial levels at glucose oral load day: Lactate_1 (a.u) 0.2542
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.4740
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.3269
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.0606
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0368
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.0923
Postpradial levels at glucose oral load day: Alanine_1 (a.u) 0.0422
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.0743
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0772
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.0231
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0137
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.0156
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0068
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.0220
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0123
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0237
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0108
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0111
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0047
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0133
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0051
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0050
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0044
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0113
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0055
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0081
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0066
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0100
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0054
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0042
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0042
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0106
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.014
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0177
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0121
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0198
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) 0.0052
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0137
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0131
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0048
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0031
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0082
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0076
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0046
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) 0.0042
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0238
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0197
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.0191
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0115
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0133
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0181
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0047
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0068
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0060
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0053
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0073
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 7e-03
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0030
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0023
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0017
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0017
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0031
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0027
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0749
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0518
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0067
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) 0.0049
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0456
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0361
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0136
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0100
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0079
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0058
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0157
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0072
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.015
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.014
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0086
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0046
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0106
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0160
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0067
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0074
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0071
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 4e-03
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0051
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.004
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0054
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0086
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0072
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0091
Basal levels at lipids oral load day: Choline_1 (a.u) 0.010
Postpradial levels at porteins oral load day: Choline_1 (a.u) 0.0091
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0157
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0141
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0140
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0107
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0156
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0113
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0281
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0133
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0278
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0153
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0248
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0094
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0194
Postpradial levels at lipids oral load day: Glycine_1 (a.u) 0.0142
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0196
Postpradial levels at glucose oral load day: Glycine_1 (a.u) 0.0079
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0291
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0187
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0062
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) 0.0093
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0083
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0050
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0061
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0113
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0105
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) 0.0072
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0084
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0079
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0155
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) 0.0123
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0060
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) 0.0038
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0092
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0092
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0097
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0081
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0050
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) 0.0041
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0028
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0037
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0036
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0062
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0393
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0757
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.0215
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0103
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0142
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0272
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.0404
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0769
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.0397
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) 0.0310
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.0477
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0254
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0032
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0034
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0033
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0017
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0037
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0023
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0078
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) 0.0045
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0068
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) 0.0050
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0054
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0113
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0043
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0038
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0030
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0033
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0050
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0045
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0035
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0032
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0023
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0018
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0028
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0038
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0043
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0031
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0021
Postpradial levels at glucose oral load day: Formate_1 (a.u) 2e-03
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0057
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0050
Mean
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0640
Mean value (a.u) Leucine_1 0.1981
Mean value (a.u) Isoleucine_1 0.0534
Mean value (a.u) L-Valine_1 0.1979
Mean value (a.u) Isobutyric acid_1 0.0212
Mean value (a.u) 2-oxoisovaleric acid_1 0.0212
Mean value (a.u) 3-Hydroxybutyric acid_1 0.1003
Mean value (a.u) Lactate_1 0.8914
Mean value (a.u) Alanine_1 0.2380
Mean value (a.u) Acetate_1 0.1682
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0573
Mean value (a.u) Acetone_1 0.0187
Mean value (a.u) L-Glutamic acid_1 0.0457
Mean value (a.u) Pyruvate_1 0.0137
Mean value (a.u) Pyroglutamic acid_1 0.0254
Mean value (a.u) L-Glutamine_1 0.1568
Mean value (a.u) Citrate_2 0.0242
Mean value (a.u) L-Asparagine_4 0.0080
Mean value (a.u) Creatinine_1 0.0627
Mean value (a.u) Creatine_1 0.0214
Mean value (a.u) Lysine_1 0.0540
Mean value (a.u) Ornithine_1 0.0215
Mean value (a.u) Choline_1 0.0302
Mean value (a.u) L-Carnitine_1 0.0954
Mean value (a.u) Betaine_1 0.0773
Mean value (a.u) Glycine_1 0.097
Mean value (a.u) L-Threonine_1 0.0237
Mean value (a.u) Glycerol_2 0.0188
Mean value (a.u) L-Serine_1 0.0225
Mean value (a.u) L-Proline_3 0.0263
Mean value (a.u) beta-Glucose_1 0.2669
Mean value (a.u) D-Glucose_2 0.4015
Mean value (a.u) 1-Methylhistidine_1 0.0157
Mean value (a.u) Tyrosine_1 0.0336
Mean value (a.u) L-Phenylalanine_2 0.0352
Mean value (a.u) L-Tryptophan_4 0.0167
Mean value (a.u) Formate_1 0.0105
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0635
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0057
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0653
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0014
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0632
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0098
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.1885
Postpradial levels at lipids oral load day: Leucine_1 (a.u) -0.0366
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.208
Postpradial levels at glucose oral load day: Leucine_1 (a.u) -0.0226
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.1983
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.1859
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0514
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) -0.0128
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0538
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) -0.0036
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0550
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0687
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.1998
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) -0.0306
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.1979
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) -0.0127
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.1962
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.1315
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0220
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) -0.0009
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0212
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) -0.0032
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0206
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0105
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0236
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0019
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0207
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0012
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0192
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0013
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0775
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0418
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.1278
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0227
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0956
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0213
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.8826
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2752
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.9666
Postpradial levels at glucose oral load day: Lactate_1 (a.u) -0.0916
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.8248
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.0645
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.2386
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0050
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.2432
Postpradial levels at glucose oral load day: Alanine_1 (a.u) -0.0228
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.2322
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0625
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.1712
Postpradial levels at lipids oral load day: Acetate_1 (a.u) -0.0071
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.1704
Postpradial levels at glucose oral load day: Acetate_1 (a.u) -0.0121
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.1628
Postpradial levels at porteins oral load day: Acetate_1 (a.u) -0.0142
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0564
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0018
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0583
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0017
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0570
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0028
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0202
Postpradial levels at lipids oral load day: Acetone_1 (a.u) -0.0016
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0167
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0062
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0193
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0042
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0446
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) -0.0019
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0462
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) -0.0027
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0461
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0201
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0147
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0094
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0157
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) -0.0001
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0109
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0102
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0197
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) -0.0070
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0324
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0003
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0242
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) -0.0051
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.1510
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) -0.0063
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.1591
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0017
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.1604
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0194
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0246
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0022
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0234
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0034
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0242
Postpradial levels at porteins oral load day: Citrate_2 (a.u) -0.0008
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0071
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0000
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0086
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) -0.0010
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0081
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0026
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0626
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) -0.0027
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0610
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) -0.0009
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0644
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) -0.0044
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0246
Postpradial levels at lipids oral load day: Creatine_1 (a.u) -0.0006
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0178
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0016
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0220
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0126
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0571
Postpradial levels at lipids oral load day: Lysine_1 (a.u) -0.0070
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0532
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0041
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0520
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0516
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0208
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) -0.0026
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0214
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 0.0005
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0223
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0048
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0279
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0016
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0297
Postpradial levels at glucose oral load day: Choline_1 (a.u) -0.0022
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0328
Postpradial levels at porteins oral load day: Choline_1 (a.u) -0.0028
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0991
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0039
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0907
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0026
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0961
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) -0.0006
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0777
Postpradial levels at lipids oral load day: Betaine_1 (a.u) -0.0058
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0715
Postpradial levels at glucose oral load day: Betaine_1 (a.u) -0.0002
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0828
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0070
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0967
Postpradial levels at lipids oral load day: Glycine_1 (a.u) -0.0068
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.1003
Postpradial levels at glucose oral load day: Glycine_1 (a.u) -0.0013
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0940
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0049
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0245
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) -0.0050
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0231
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) -0.0005
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0234
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0147
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0160
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) -0.0019
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0202
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) -0.0035
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0200
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) -0.0073
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0214
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) -0.0015
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0221
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) -0.0009
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0238
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0086
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0246
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) -0.0041
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0272
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0016
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0271
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0138
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.2791
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.1000
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.2676
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) -0.0088
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.2541
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0133
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.4046
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.1283
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.4068
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) -0.0140
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.3934
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) -0.0035
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0145
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0001
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0155
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) -0.0003
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0171
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0036
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0322
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) -0.0045
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0357
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) -0.0041
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0328
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0269
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0362
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) -0.0045
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0344
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) -0.0011
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0347
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0120
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0162
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) -0.0018
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0179
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) -0.0021
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0161
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0045
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0107
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0002
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0111
Postpradial levels at glucose oral load day: Formate_1 (a.u) -0.0010
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0097
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0007
SD
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0076
Mean value (a.u) Leucine_1 0.0173
Mean value (a.u) Isoleucine_1 0.0080
Mean value (a.u) L-Valine_1 0.0205
Mean value (a.u) Isobutyric acid_1 0.0032
Mean value (a.u) 2-oxoisovaleric acid_1 0.0020
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0787
Mean value (a.u) Lactate_1 0.2428
Mean value (a.u) Alanine_1 0.0557
Mean value (a.u) Acetate_1 0.0269
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0129
Mean value (a.u) Acetone_1 0.0026
Mean value (a.u) L-Glutamic acid_1 0.0076
Mean value (a.u) Pyruvate_1 0.0063
Mean value (a.u) Pyroglutamic acid_1 0.0127
Mean value (a.u) L-Glutamine_1 0.0118
Mean value (a.u) Citrate_2 0.0032
Mean value (a.u) L-Asparagine_4 0.0014
Mean value (a.u) Creatinine_1 0.0066
Mean value (a.u) Creatine_1 0.0080
Mean value (a.u) Lysine_1 0.0088
Mean value (a.u) Ornithine_1 0.0054
Mean value (a.u) Choline_1 0.0092
Mean value (a.u) L-Carnitine_1 0.0093
Mean value (a.u) Betaine_1 0.0114
Mean value (a.u) Glycine_1 0.010
Mean value (a.u) L-Threonine_1 0.0054
Mean value (a.u) Glycerol_2 0.0039
Mean value (a.u) L-Serine_1 0.0047
Mean value (a.u) L-Proline_3 0.0033
Mean value (a.u) beta-Glucose_1 0.0238
Mean value (a.u) D-Glucose_2 0.0241
Mean value (a.u) 1-Methylhistidine_1 0.0028
Mean value (a.u) Tyrosine_1 0.0065
Mean value (a.u) L-Phenylalanine_2 0.0048
Mean value (a.u) L-Tryptophan_4 0.0027
Mean value (a.u) Formate_1 0.0009
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0097
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0043
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0138
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0099
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0101
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0160
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.0267
Postpradial levels at lipids oral load day: Leucine_1 (a.u) 0.0116
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.024
Postpradial levels at glucose oral load day: Leucine_1 (a.u) 0.0156
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.0282
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0738
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0080
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) 0.0058
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0100
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) 0.0041
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0125
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0216
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.0317
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) 0.0204
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0277
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) 0.0152
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.0224
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0381
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0074
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0058
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0039
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0024
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0068
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0077
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0044
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0035
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0050
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0049
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0043
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0033
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0456
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0337
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.1949
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0581
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0541
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0358
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.2112
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.2112
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.4722
Postpradial levels at glucose oral load day: Lactate_1 (a.u) 0.3599
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.1733
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.1087
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.0482
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0167
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.0689
Postpradial levels at glucose oral load day: Alanine_1 (a.u) 0.0299
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.0613
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0352
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.0289
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0222
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.0403
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0102
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.0330
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0191
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0147
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0030
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0129
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0041
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0123
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0025
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0044
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0031
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0040
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0043
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0049
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0065
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0108
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0046
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0067
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0043
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0089
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0079
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0083
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0056
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0098
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) 0.0072
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0052
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0059
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0089
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0065
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0326
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0102
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0081
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) 0.0063
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0155
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0125
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.0141
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0117
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0136
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0129
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0065
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0044
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0045
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0049
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0046
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0032
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0020
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0012
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0020
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0015
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0014
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0018
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0077
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0075
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0098
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) 0.0089
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0066
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0053
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0099
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0079
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0038
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0086
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0061
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0118
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.0092
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0092
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0081
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0103
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0177
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0073
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0053
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0076
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 0.0053
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0054
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0043
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0141
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0088
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0126
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0068
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0143
Postpradial levels at porteins oral load day: Choline_1 (a.u) 0.0138
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0125
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0114
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0141
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0120
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0149
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0112
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0209
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0110
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0160
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0107
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0109
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0066
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0141
Postpradial levels at lipids oral load day: Glycine_1 (a.u) 0.0077
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0142
Postpradial levels at glucose oral load day: Glycine_1 (a.u) 0.0104
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0101
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0074
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0096
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) 0.0041
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0073
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0052
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0076
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0058
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0061
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) 0.0067
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0099
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0063
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0035
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) 0.0035
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0073
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) 0.0063
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0056
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0067
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0074
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0043
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0071
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) 0.0047
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0085
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0058
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0035
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0071
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0386
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0777
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.0170
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0117
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0248
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0162
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.0423
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0856
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.0320
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) 0.0238
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.0396
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0306
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0030
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0013
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0030
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0021
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0038
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0025
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0082
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) 0.0056
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0089
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) 0.0065
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0072
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0124
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0055
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0025
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0064
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0034
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0052
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0052
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0048
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0033
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0032
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0027
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0028
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0029
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0020
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0018
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0012
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0015
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0018
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0022
Mean
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0597
Mean value (a.u) Leucine_1 0.1878
Mean value (a.u) Isoleucine_1 0.0519
Mean value (a.u) L-Valine_1 0.1830
Mean value (a.u) Isobutyric acid_1 0.021
Mean value (a.u) 2-oxoisovaleric acid_1 0.0207
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0540
Mean value (a.u) Lactate_1 1.1284
Mean value (a.u) Alanine_1 0.2902
Mean value (a.u) Acetate_1 0.1771
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0513
Mean value (a.u) Acetone_1 0.0223
Mean value (a.u) L-Glutamic acid_1 0.0524
Mean value (a.u) Pyruvate_1 0.0180
Mean value (a.u) Pyroglutamic acid_1 0.0154
Mean value (a.u) L-Glutamine_1 0.1516
Mean value (a.u) Citrate_2 0.0194
Mean value (a.u) L-Asparagine_4 0.0070
Mean value (a.u) Creatinine_1 0.0523
Mean value (a.u) Creatine_1 0.0279
Mean value (a.u) Lysine_1 0.0499
Mean value (a.u) Ornithine_1 0.0224
Mean value (a.u) Choline_1 0.0256
Mean value (a.u) L-Carnitine_1 0.0810
Mean value (a.u) Betaine_1 0.0629
Mean value (a.u) Glycine_1 0.0940
Mean value (a.u) L-Threonine_1 0.0209
Mean value (a.u) Glycerol_2 0.0189
Mean value (a.u) L-Serine_1 0.0226
Mean value (a.u) L-Proline_3 0.0236
Mean value (a.u) beta-Glucose_1 0.2649
Mean value (a.u) D-Glucose_2 0.3862
Mean value (a.u) 1-Methylhistidine_1 0.015
Mean value (a.u) Tyrosine_1 0.0358
Mean value (a.u) L-Phenylalanine_2 0.0359
Mean value (a.u) L-Tryptophan_4 0.0168
Mean value (a.u) Formate_1 0.0131
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0601
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0085
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0595
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) -0.0012
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0596
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0091
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.1729
Postpradial levels at lipids oral load day: Leucine_1 (a.u) -0.0264
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.1922
Postpradial levels at glucose oral load day: Leucine_1 (a.u) -0.0214
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.1985
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.1205
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0446
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) -0.0089
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0533
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) -0.0063
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0577
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0453
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.1712
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) -0.0172
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.1879
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) -0.0188
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.1896
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0856
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0222
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) -0.0012
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0216
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) -0.0035
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0195
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0094
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0210
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0005
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0208
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0002
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0204
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) -0.0002
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0527
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0245
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0446
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0260
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0644
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) -0.0154
Basal levels at glucose oral load day: Lactate_1 (a.u) 1.0779
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.1720
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 1.0979
Postpradial levels at glucose oral load day: Lactate_1 (a.u) -0.2321
Basal levels at lipids oral load day: Lactate_1 (a.u) 1.2094
Postpradial levels at porteins oral load day: Lactate_1 (a.u) -0.1341
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.2793
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0108
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.2885
Postpradial levels at glucose oral load day: Alanine_1 (a.u) -0.0281
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.3027
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0572
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.1749
Postpradial levels at lipids oral load day: Acetate_1 (a.u) -0.0019
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.1717
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0040
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.1848
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0038
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0482
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0012
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0525
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0028
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0533
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) -0.0027
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0214
Postpradial levels at lipids oral load day: Acetone_1 (a.u) -0.0023
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0223
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0037
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0229
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0012
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0498
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0006
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0534
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) -0.0054
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0543
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0140
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0215
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0067
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0150
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) -0.0001
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0172
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0083
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0142
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) -0.0042
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0139
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0044
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0180
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) -0.0017
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.144
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) -0.0044
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.1558
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) -0.0024
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.1549
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0125
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0195
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0025
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0187
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0006
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0200
Postpradial levels at porteins oral load day: Citrate_2 (a.u) -0.0001
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0059
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0005
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0076
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) -0.0006
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0072
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0020
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0496
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0004
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0515
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) -0.0027
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0555
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) -0.0011
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0264
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0003
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0259
Postpradial levels at glucose oral load day: Creatine_1 (a.u) -0.0006
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0313
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0080
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0463
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.0011
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0516
Postpradial levels at glucose oral load day: Lysine_1 (a.u) -0.0026
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0519
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0338
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0198
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0007
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0226
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) -0.0030
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0249
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0007
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0266
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0011
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0212
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0065
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0290
Postpradial levels at porteins oral load day: Choline_1 (a.u) -0.0016
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0843
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) -0.0046
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0748
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0070
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0841
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) -0.0034
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0573
Postpradial levels at lipids oral load day: Betaine_1 (a.u) -0.0046
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0536
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0014
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0780
Postpradial levels at porteins oral load day: Betaine_1 (a.u) -0.0008
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0890
Postpradial levels at lipids oral load day: Glycine_1 (a.u) -0.0025
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0956
Postpradial levels at glucose oral load day: Glycine_1 (a.u) -0.0065
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0974
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0005
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0206
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) -0.0031
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0180
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0026
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0239
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0096
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0180
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) -0.0051
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0181
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) -0.0011
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0205
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) -0.0054
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0232
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) -0.0038
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0227
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) -0.0010
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0219
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0060
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0248
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) -0.0023
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0201
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0031
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0261
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0094
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.2673
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.1456
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.2624
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) -0.0093
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.2652
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0072
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.3847
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.1876
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.3822
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) -0.0006
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.3918
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0059
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0146
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) -0.0006
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0154
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) -0.0008
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0150
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0016
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0344
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) -0.0036
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0348
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) -0.0016
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0379
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0162
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0336
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) -0.0014
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0379
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) -0.0055
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0360
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0073
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0156
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) -0.0007
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0181
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) -0.0033
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0166
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0014
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0129
Postpradial levels at lipids oral load day: Formate_1 (a.u) -0.0003
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0131
Postpradial levels at glucose oral load day: Formate_1 (a.u) -0.0001
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0135
Postpradial levels at porteins oral load day: Formate_1 (a.u) -0.0001
SD
Mean value (a.u) 2-Oxoisocaproic acid_2 0.0068
Mean value (a.u) Leucine_1 0.0226
Mean value (a.u) Isoleucine_1 0.0074
Mean value (a.u) L-Valine_1 0.0213
Mean value (a.u) Isobutyric acid_1 0.007
Mean value (a.u) 2-oxoisovaleric acid_1 0.0024
Mean value (a.u) 3-Hydroxybutyric acid_1 0.0305
Mean value (a.u) Lactate_1 0.3531
Mean value (a.u) Alanine_1 0.0622
Mean value (a.u) Acetate_1 0.0766
Mean value (a.u) N-Ac-Glycoprotein_signals_1 0.0104
Mean value (a.u) Acetone_1 0.0041
Mean value (a.u) L-Glutamic acid_1 0.0099
Mean value (a.u) Pyruvate_1 0.0055
Mean value (a.u) Pyroglutamic acid_1 0.0050
Mean value (a.u) L-Glutamine_1 0.0240
Mean value (a.u) Citrate_2 0.0022
Mean value (a.u) L-Asparagine_4 0.0011
Mean value (a.u) Creatinine_1 0.0093
Mean value (a.u) Creatine_1 0.0119
Mean value (a.u) Lysine_1 0.0088
Mean value (a.u) Ornithine_1 0.0061
Mean value (a.u) Choline_1 0.0085
Mean value (a.u) L-Carnitine_1 0.0188
Mean value (a.u) Betaine_1 0.0213
Mean value (a.u) Glycine_1 0.0257
Mean value (a.u) L-Threonine_1 0.0066
Mean value (a.u) Glycerol_2 0.0069
Mean value (a.u) L-Serine_1 0.0055
Mean value (a.u) L-Proline_3 0.0041
Mean value (a.u) beta-Glucose_1 0.0312
Mean value (a.u) D-Glucose_2 0.0508
Mean value (a.u) 1-Methylhistidine_1 0.004
Mean value (a.u) Tyrosine_1 0.0051
Mean value (a.u) L-Phenylalanine_2 0.0054
Mean value (a.u) L-Tryptophan_4 0.0018
Mean value (a.u) Formate_1 0.0014
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0077
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0065
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0109
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0112
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0089
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) 0.0089
Basal levels at glucose oral load day: Leucine_1 (a.u) 0.0280
Postpradial levels at lipids oral load day: Leucine_1 (a.u) 0.0135
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) 0.0241
Postpradial levels at glucose oral load day: Leucine_1 (a.u) 0.0172
Basal levels at lipids oral load day: Leucine_1 (a.u) 0.0397
Postpradial levels at porteins oral load day: Leucine_1 (a.u) 0.0331
Basal levels at glucose oral load day: Isoleucine_1 (a.u) 0.0096
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) 0.0076
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) 0.0111
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) 0.0094
Basal levels at lipids oral load day: Isoleucine_1 (a.u) 0.0119
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) 0.0130
Basal levels at glucose oral load day: L-Valine_1 (a.u) 0.0119
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) 0.0127
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) 0.0331
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) 0.0222
Basal levels at lipids oral load day: L-Valine_1 (a.u) 0.0312
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) 0.0211
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0060
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0048
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) 0.0075
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) 0.0062
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) 0.0101
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) 0.0051
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0034
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0038
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0033
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0023
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0041
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) 0.0027
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0465
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0338
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0209
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0301
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0573
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) 0.0312
Basal levels at glucose oral load day: Lactate_1 (a.u) 0.2999
Postpradial levels at lipids oral load day: Lactate_1 (a.u) 0.1334
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) 0.4172
Postpradial levels at glucose oral load day: Lactate_1 (a.u) 0.1755
Basal levels at lipids oral load day: Lactate_1 (a.u) 0.4606
Postpradial levels at porteins oral load day: Lactate_1 (a.u) 0.2079
Basal levels at glucose oral load day: Alanine_1 (a.u) 0.0663
Postpradial levels at lipids oral load day: Alanine_1 (a.u) 0.0303
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) 0.0814
Postpradial levels at glucose oral load day: Alanine_1 (a.u) 0.0197
Basal levels at lipids oral load day: Alanine_1 (a.u) 0.0871
Postpradial levels at porteins oral load day: Alanine_1 (a.u) 0.0268
Basal levels at glucose oral load day: Acetate_1 (a.u) 0.0806
Postpradial levels at lipids oral load day: Acetate_1 (a.u) 0.0103
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) 0.0744
Postpradial levels at glucose oral load day: Acetate_1 (a.u) 0.0139
Basal levels at lipids oral load day: Acetate_1 (a.u) 0.0817
Postpradial levels at porteins oral load day: Acetate_1 (a.u) 0.0330
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0091
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0027
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0116
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0045
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0110
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) 0.0033
Basal levels at glucose oral load day: Acetone_1 (a.u) 0.0047
Postpradial levels at lipids oral load day: Acetone_1 (a.u) 0.0051
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) 0.0067
Postpradial levels at glucose oral load day: Acetone_1 (a.u) 0.0051
Basal levels at lipids oral load day: Acetone_1 (a.u) 0.0073
Postpradial levels at porteins oral load day: Acetone_1 (a.u) 0.0060
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0076
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0043
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) 0.0126
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) 0.0065
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) 0.0100
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) 0.0076
Basal levels at glucose oral load day: Pyruvate_1 (a.u) 0.0080
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) 0.0045
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) 0.0078
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) 0.0041
Basal levels at lipids oral load day: Pyruvate_1 (a.u) 0.0069
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) 0.0058
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0084
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0046
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) 0.0045
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) 0.0069
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) 0.0104
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) 0.0066
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) 0.023
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0099
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) 0.0245
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) 0.0084
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) 0.0285
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) 0.0054
Basal levels at glucose oral load day: Citrate_2 (a.u) 0.0041
Postpradial levels at lipids oral load day: Citrate_2 (a.u) 0.0038
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) 0.0032
Postpradial levels at glucose oral load day: Citrate_2 (a.u) 0.0024
Basal levels at lipids oral load day: Citrate_2 (a.u) 0.0043
Postpradial levels at porteins oral load day: Citrate_2 (a.u) 0.0024
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0022
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0014
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) 0.0012
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) 0.0018
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) 0.0012
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) 0.0012
Basal levels at glucose oral load day: Creatinine_1 (a.u) 0.0096
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) 0.0073
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) 0.0083
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) 0.0076
Basal levels at lipids oral load day: Creatinine_1 (a.u) 0.0133
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) 0.0112
Basal levels at glucose oral load day: Creatine_1 (a.u) 0.0104
Postpradial levels at lipids oral load day: Creatine_1 (a.u) 0.0044
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) 0.0142
Postpradial levels at glucose oral load day: Creatine_1 (a.u) 0.0056
Basal levels at lipids oral load day: Creatine_1 (a.u) 0.0170
Postpradial levels at porteins oral load day: Creatine_1 (a.u) 0.0066
Basal levels at glucose oral load day: Lysine_1 (a.u) 0.0070
Postpradial levels at lipids oral load day: Lysine_1 (a.u) 0.0057
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) 0.0102
Postpradial levels at glucose oral load day: Lysine_1 (a.u) 0.0061
Basal levels at lipids oral load day: Lysine_1 (a.u) 0.0159
Postpradial levels at porteins oral load day: Lysine_1 (a.u) 0.0091
Basal levels at glucose oral load day: Ornithine_1 (a.u) 0.0050
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) 0.0025
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) 0.0059
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) 0.0035
Basal levels at lipids oral load day: Ornithine_1 (a.u) 0.0109
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) 0.0077
Basal levels at glucose oral load day: Choline_1 (a.u) 0.0109
Postpradial levels at lipids oral load day: Choline_1 (a.u) 0.0115
Basal levels at glucose proteins oral load day: Choline_1 (a.u) 0.0100
Postpradial levels at glucose oral load day: Choline_1 (a.u) 0.0125
Basal levels at lipids oral load day: Choline_1 (a.u) 0.0116
Postpradial levels at porteins oral load day: Choline_1 (a.u) 0.0074
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0243
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0101
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) 0.0256
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) 0.0207
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) 0.0204
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) 0.0131
Basal levels at glucose oral load day: Betaine_1 (a.u) 0.0167
Postpradial levels at lipids oral load day: Betaine_1 (a.u) 0.0080
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) 0.0188
Postpradial levels at glucose oral load day: Betaine_1 (a.u) 0.0100
Basal levels at lipids oral load day: Betaine_1 (a.u) 0.0441
Postpradial levels at porteins oral load day: Betaine_1 (a.u) 0.0124
Basal levels at glucose oral load day: Glycine_1 (a.u) 0.0281
Postpradial levels at lipids oral load day: Glycine_1 (a.u) 0.0110
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) 0.0249
Postpradial levels at glucose oral load day: Glycine_1 (a.u) 0.0067
Basal levels at lipids oral load day: Glycine_1 (a.u) 0.0283
Postpradial levels at porteins oral load day: Glycine_1 (a.u) 0.0038
Basal levels at glucose oral load day: L-Threonine_1 (a.u) 0.0079
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) 0.0039
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) 0.0068
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) 0.0064
Basal levels at lipids oral load day: L-Threonine_1 (a.u) 0.0111
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) 0.0051
Basal levels at glucose oral load day: Glycerol_2 (a.u) 0.0068
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) 0.0050
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) 0.0087
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) 0.0065
Basal levels at lipids oral load day: Glycerol_2 (a.u) 0.0096
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) 0.0055
Basal levels at glucose oral load day: L-Serine_1 (a.u) 0.0066
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) 0.0051
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) 0.0076
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) 0.0061
Basal levels at lipids oral load day: L-Serine_1 (a.u) 0.0062
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) 0.0036
Basal levels at glucose oral load day: L-Proline_3 (a.u) 0.0061
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) 0.0021
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) 0.0044
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) 0.0043
Basal levels at lipids oral load day: L-Proline_3 (a.u) 0.0077
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) 0.0078
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0273
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0703
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) 0.0363
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) 0.0214
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) 0.0379
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) 0.0132
Basal levels at glucose oral load day: D-Glucose_2 (a.u) 0.0544
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) 0.0818
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) 0.0682
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) 0.0502
Basal levels at lipids oral load day: D-Glucose_2 (a.u) 0.0763
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) 0.0442
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0038
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0023
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) 0.0037
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) 0.0015
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) 0.0054
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) 0.0022
Basal levels at glucose oral load day: Tyrosine_1 (a.u) 0.0065
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) 0.0042
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) 0.0071
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) 0.0041
Basal levels at lipids oral load day: Tyrosine_1 (a.u) 0.0067
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) 0.0062
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0051
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0029
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) 0.0065
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) 0.0053
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) 0.0077
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) 0.0016
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0026
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0027
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) 0.0034
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) 0.0028
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) 0.0048
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) 0.0037
Basal levels at glucose oral load day: Formate_1 (a.u) 0.0020
Postpradial levels at lipids oral load day: Formate_1 (a.u) 0.0014
Basal levels at glucose proteins oral load day: Formate_1 (a.u) 0.0013
Postpradial levels at glucose oral load day: Formate_1 (a.u) 0.0014
Basal levels at lipids oral load day: Formate_1 (a.u) 0.0022
Postpradial levels at porteins oral load day: Formate_1 (a.u) 0.0013
variable Code
Mean value (a.u) 2-Oxoisocaproic acid_2 Oxoisocaproic_mean
Mean value (a.u) Leucine_1 Leu_mean
Mean value (a.u) Isoleucine_1 Isoleu_mean
Mean value (a.u) L-Valine_1 Valine_mean
Mean value (a.u) Isobutyric acid_1 Isobutyric_mean
Mean value (a.u) 2-oxoisovaleric acid_1 Oxoisovaleric_mean
Mean value (a.u) 3-Hydroxybutyric acid_1 OHbutyric_mean
Mean value (a.u) Lactate_1 Lactate_mean
Mean value (a.u) Alanine_1 Alanine_mean
Mean value (a.u) Acetate_1 Acetate_mean
Mean value (a.u) N-Ac-Glycoprotein_signals_1 Glycoprot_mean
Mean value (a.u) Acetone_1 Acetone_mean
Mean value (a.u) L-Glutamic acid_1 Gluacid_mean
Mean value (a.u) Pyruvate_1 Pyruvate_mean
Mean value (a.u) Pyroglutamic acid_1 Pyroglu_mean
Mean value (a.u) L-Glutamine_1 Gln_mean
Mean value (a.u) Citrate_2 Citrate_mean
Mean value (a.u) L-Asparagine_4 Asn_mean
Mean value (a.u) Creatinine_1 Creatinine_mean
Mean value (a.u) Creatine_1 Creatine_mean
Mean value (a.u) Lysine_1 Lysine_mean
Mean value (a.u) Ornithine_1 Ornithine_mean
Mean value (a.u) Choline_1 Choline_mean
Mean value (a.u) L-Carnitine_1 Carnitine_mean
Mean value (a.u) Betaine_1 Betaine_mean
Mean value (a.u) Glycine_1 Glycine_mean
Mean value (a.u) L-Threonine_1 Threonine_mean
Mean value (a.u) Glycerol_2 Glycerol_mean
Mean value (a.u) L-Serine_1 Serine_mean
Mean value (a.u) L-Proline_3 Proline_mean
Mean value (a.u) beta-Glucose_1 BGlucose_mean
Mean value (a.u) D-Glucose_2 DGlucose_mean
Mean value (a.u) 1-Methylhistidine_1 Methys_mean
Mean value (a.u) Tyrosine_1 Tyrosine_mean
Mean value (a.u) L-Phenylalanine_2 Phe_mean
Mean value (a.u) L-Tryptophan_4 Tryp_mean
Mean value (a.u) Formate_1 Formate_mean
Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) Oxoisocaproic_G0
Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) Oxoisocap_AUCgluc
Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) Oxoisocaproic_L0
Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) Oxoisocap_AUClipid
Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) Oxoisocaproic_P0
Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) Oxoisocap_AUCprot
Basal levels at glucose oral load day: Leucine_1 (a.u) Leu_G0
Postpradial levels at lipids oral load day: Leucine_1 (a.u) Leu_AUCgluc
Basal levels at glucose proteins oral load day: Leucine_1 (a.u) Leu_L0
Postpradial levels at glucose oral load day: Leucine_1 (a.u) Leu_AUClipid
Basal levels at lipids oral load day: Leucine_1 (a.u) Leu_P0
Postpradial levels at porteins oral load day: Leucine_1 (a.u) Leu_AUCprot
Basal levels at glucose oral load day: Isoleucine_1 (a.u) Isoleu_G0
Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) Isoleu_AUGgluc
Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) Isoleu_L0
Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) Isoleu_AUGlipid
Basal levels at lipids oral load day: Isoleucine_1 (a.u) Isoleu_P0
Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) Isoleu_AUGprot
Basal levels at glucose oral load day: L-Valine_1 (a.u) Valine_G0
Postpradial levels at lipids oral load day: L-Valine_1 (a.u) Valine_AUGgluc
Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) Valine_L0
Postpradial levels at glucose oral load day: L-Valine_1 (a.u) Valine_AUGlipid
Basal levels at lipids oral load day: L-Valine_1 (a.u) Valine_P0
Postpradial levels at porteins oral load day: L-Valine_1 (a.u) Valine_AUGprot
Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) Isobutyric_G0
Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) Isobutyric_AUGgluc
Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) Isobutyric_L0
Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) Isobutyric_AUGlipid
Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) Isobutyric_P0
Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) Isobutyric_AUGprot
Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) Oxoisovaleric_G0
Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) Oxoisovaleric_AUGgluc
Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) Oxoisovaleric_L0
Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) Oxoisovaleric_AUGlipid
Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) Oxoisovaleric_P0
Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) Oxoisovaleric_AUGprot
Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) OHbutyric_G0
Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) OHbutyric_AUGgluc
Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) OHbutyric_L0
Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) OHbutyric_AUGlipid
Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) OHbutyric_P0
Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) OHbutyric_AUGprot
Basal levels at glucose oral load day: Lactate_1 (a.u) Lactate_G0
Postpradial levels at lipids oral load day: Lactate_1 (a.u) Lactate_AUGgluc
Basal levels at glucose proteins oral load day: Lactate_1 (a.u) Lactate_L0
Postpradial levels at glucose oral load day: Lactate_1 (a.u) Lactate_AUGlipid
Basal levels at lipids oral load day: Lactate_1 (a.u) Lactate_P0
Postpradial levels at porteins oral load day: Lactate_1 (a.u) Lactate_AUGprot
Basal levels at glucose oral load day: Alanine_1 (a.u) Alanine_G0
Postpradial levels at lipids oral load day: Alanine_1 (a.u) Alanine_AUGgluc
Basal levels at glucose proteins oral load day: Alanine_1 (a.u) Alanine_L0
Postpradial levels at glucose oral load day: Alanine_1 (a.u) Alanine_AUGlipid
Basal levels at lipids oral load day: Alanine_1 (a.u) Alanine_P0
Postpradial levels at porteins oral load day: Alanine_1 (a.u) Alanine_AUGprot
Basal levels at glucose oral load day: Acetate_1 (a.u) Acetate_G0
Postpradial levels at lipids oral load day: Acetate_1 (a.u) Acetate_AUGgluc
Basal levels at glucose proteins oral load day: Acetate_1 (a.u) Acetate_L0
Postpradial levels at glucose oral load day: Acetate_1 (a.u) Acetate_AUGlipid
Basal levels at lipids oral load day: Acetate_1 (a.u) Acetate_P0
Postpradial levels at porteins oral load day: Acetate_1 (a.u) Acetate_AUGprot
Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) Glycoprot_G0
Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) Glycoprot_AUGgluc
Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) Glycoprot_L0
Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) Glycoprot_AUGlipid
Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) Glycoprot_P0
Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) Glycoprot_AUGprot
Basal levels at glucose oral load day: Acetone_1 (a.u) Acetone_G0
Postpradial levels at lipids oral load day: Acetone_1 (a.u) Acetone_AUGgluc
Basal levels at glucose proteins oral load day: Acetone_1 (a.u) Acetone_L0
Postpradial levels at glucose oral load day: Acetone_1 (a.u) Acetone_AUGlipid
Basal levels at lipids oral load day: Acetone_1 (a.u) Acetone_P0
Postpradial levels at porteins oral load day: Acetone_1 (a.u) Acetone_AUGprot
Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) Gluacid_G0
Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) Gluacid_AUGgluc
Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) Gluacid_L0
Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) Gluacid_AUGlipid
Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) Gluacid_P0
Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) Gluacid_AUGprot
Basal levels at glucose oral load day: Pyruvate_1 (a.u) Pyruvate_G0
Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) Pyruvate_AUGgluc
Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) Pyruvate_L0
Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) Pyruvate_AUGlipid
Basal levels at lipids oral load day: Pyruvate_1 (a.u) Pyruvate_P0
Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) Pyruvate_AUGprot
Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) Pyroglu_G0
Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) Pyroglu_AUGgluc
Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) Pyroglu_L0
Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) Pyroglu_AUGlipid
Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) Pyroglu_P0
Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) Pyroglu_AUGprot
Basal levels at glucose oral load day: L-Glutamine_1 (a.u) Gln_G0
Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) Gln_AUGgluc
Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) Gln_L0
Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) Gln_AUGlipid
Basal levels at lipids oral load day: L-Glutamine_1 (a.u) Gln_P0
Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) Gln_AUGprot
Basal levels at glucose oral load day: Citrate_2 (a.u) Citrate_G0
Postpradial levels at lipids oral load day: Citrate_2 (a.u) Citrate_AUGgluc
Basal levels at glucose proteins oral load day: Citrate_2 (a.u) Citrate_L0
Postpradial levels at glucose oral load day: Citrate_2 (a.u) Citrate_AUGlipid
Basal levels at lipids oral load day: Citrate_2 (a.u) Citrate_P0
Postpradial levels at porteins oral load day: Citrate_2 (a.u) Citrate_AUGprot
Basal levels at glucose oral load day: L-Asparagine_4 (a.u) Asn_G0
Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) Asn_AUGgluc
Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) Asn_L0
Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) Asn_AUGlipid
Basal levels at lipids oral load day: L-Asparagine_4 (a.u) Asn_P0
Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) Asn_AUGprot
Basal levels at glucose oral load day: Creatinine_1 (a.u) Creatinine_G0
Postpradial levels at lipids oral load day: Creatinine_1 (a.u) Creatinine_AUGgluc
Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) Creatinine_L0
Postpradial levels at glucose oral load day: Creatinine_1 (a.u) Creatinine_AUGlipid
Basal levels at lipids oral load day: Creatinine_1 (a.u) Creatinine_P0
Postpradial levels at porteins oral load day: Creatinine_1 (a.u) Creatinine_AUGprot
Basal levels at glucose oral load day: Creatine_1 (a.u) Creatine_G0
Postpradial levels at lipids oral load day: Creatine_1 (a.u) Creatine_AUGgluc
Basal levels at glucose proteins oral load day: Creatine_1 (a.u) Creatine_L0
Postpradial levels at glucose oral load day: Creatine_1 (a.u) Creatine_AUGlipid
Basal levels at lipids oral load day: Creatine_1 (a.u) Creatine_P0
Postpradial levels at porteins oral load day: Creatine_1 (a.u) Creatine_AUGprot
Basal levels at glucose oral load day: Lysine_1 (a.u) Lysine_G0
Postpradial levels at lipids oral load day: Lysine_1 (a.u) Lysine_AUGgluc
Basal levels at glucose proteins oral load day: Lysine_1 (a.u) Lysine_L0
Postpradial levels at glucose oral load day: Lysine_1 (a.u) Lysine_AUGlipid
Basal levels at lipids oral load day: Lysine_1 (a.u) Lysine_P0
Postpradial levels at porteins oral load day: Lysine_1 (a.u) Lysine_AUGprot
Basal levels at glucose oral load day: Ornithine_1 (a.u) Ornithine_G0
Postpradial levels at lipids oral load day: Ornithine_1 (a.u) Ornithine_AUGgluc
Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) Ornithine_L0
Postpradial levels at glucose oral load day: Ornithine_1 (a.u) Ornithine_AUGlipid
Basal levels at lipids oral load day: Ornithine_1 (a.u) Ornithine_P0
Postpradial levels at porteins oral load day: Ornithine_1 (a.u) Ornithine_AUGprot
Basal levels at glucose oral load day: Choline_1 (a.u) Choline_G0
Postpradial levels at lipids oral load day: Choline_1 (a.u) Choline_AUGgluc
Basal levels at glucose proteins oral load day: Choline_1 (a.u) Choline_L0
Postpradial levels at glucose oral load day: Choline_1 (a.u) Choline_AUGlipid
Basal levels at lipids oral load day: Choline_1 (a.u) Choline_P0
Postpradial levels at porteins oral load day: Choline_1 (a.u) Choline_AUGprot
Basal levels at glucose oral load day: L-Carnitine_1 (a.u) Carnitine_G0
Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) Carnitine_AUGgluc
Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) Carnitine_L0
Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) Carnitine_AUGlipid
Basal levels at lipids oral load day: L-Carnitine_1 (a.u) Carnitine_P0
Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) Carnitine_AUGprot
Basal levels at glucose oral load day: Betaine_1 (a.u) Betaine_G0
Postpradial levels at lipids oral load day: Betaine_1 (a.u) Betaine_AUGgluc
Basal levels at glucose proteins oral load day: Betaine_1 (a.u) Betaine_L0
Postpradial levels at glucose oral load day: Betaine_1 (a.u) Betaine_AUGlipid
Basal levels at lipids oral load day: Betaine_1 (a.u) Betaine_P0
Postpradial levels at porteins oral load day: Betaine_1 (a.u) Betaine_AUGprot
Basal levels at glucose oral load day: Glycine_1 (a.u) Glycine_G0
Postpradial levels at lipids oral load day: Glycine_1 (a.u) Glycine_AUGgluc
Basal levels at glucose proteins oral load day: Glycine_1 (a.u) Glycine_L0
Postpradial levels at glucose oral load day: Glycine_1 (a.u) Glycine_AUGlipid
Basal levels at lipids oral load day: Glycine_1 (a.u) Glycine_P0
Postpradial levels at porteins oral load day: Glycine_1 (a.u) Glycine_AUGprot
Basal levels at glucose oral load day: L-Threonine_1 (a.u) Threonine_G0
Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) Threonine_AUGgluc
Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) Threonine_L0
Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) Threonine_AUGlipid
Basal levels at lipids oral load day: L-Threonine_1 (a.u) Threonine_P0
Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) Threonine_AUGprot
Basal levels at glucose oral load day: Glycerol_2 (a.u) Glycerol_G0
Postpradial levels at lipids oral load day: Glycerol_2 (a.u) Glycerol_AUGgluc
Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) Glycerol_L0
Postpradial levels at glucose oral load day: Glycerol_2 (a.u) Glycerol_AUGlipid
Basal levels at lipids oral load day: Glycerol_2 (a.u) Glycerol_P0
Postpradial levels at porteins oral load day: Glycerol_2 (a.u) Glycerol_AUGprot
Basal levels at glucose oral load day: L-Serine_1 (a.u) Serine_G0
Postpradial levels at lipids oral load day: L-Serine_1 (a.u) Serine_AUGgluc
Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) Serine_L0
Postpradial levels at glucose oral load day: L-Serine_1 (a.u) Serine_AUGlipid
Basal levels at lipids oral load day: L-Serine_1 (a.u) Serine_P0
Postpradial levels at porteins oral load day: L-Serine_1 (a.u) Serine_AUGprot
Basal levels at glucose oral load day: L-Proline_3 (a.u) Proline_G0
Postpradial levels at lipids oral load day: L-Proline_3 (a.u) Proline_AUGgluc
Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) Proline_L0
Postpradial levels at glucose oral load day: L-Proline_3 (a.u) Proline_AUGlipid
Basal levels at lipids oral load day: L-Proline_3 (a.u) Proline_P0
Postpradial levels at porteins oral load day: L-Proline_3 (a.u) Proline_AUGprot
Basal levels at glucose oral load day: beta-Glucose_1 (a.u) BGlucose_G0
Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) BGlucose_AUGgluc
Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) BGlucose_L0
Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) BGlucose_AUGlipid
Basal levels at lipids oral load day: beta-Glucose_1 (a.u) BGlucose_P0
Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) BGlucose_AUGprot
Basal levels at glucose oral load day: D-Glucose_2 (a.u) Dglucose_G0
Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) Dglucose_AUGgluc
Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) Dglucose_L0
Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) Dglucose_AUGlipid
Basal levels at lipids oral load day: D-Glucose_2 (a.u) Dglucose_P0
Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) Dglucose_AUGprot
Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) Methys_G0
Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) Methys_AUGgluc
Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) Methys_L0
Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) Methys_AUGlipid
Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) Methys_P0
Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) Methys_AUGprot
Basal levels at glucose oral load day: Tyrosine_1 (a.u) Tyrosine_G0
Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) Tyrosine_AUGgluc
Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) Tyrosine_L0
Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) Tyrosine_AUGlipid
Basal levels at lipids oral load day: Tyrosine_1 (a.u) Tyrosine_P0
Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) Tyrosine_AUGprot
Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) Phe_G0
Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) Phe_AUGgluc
Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) Phe_L0
Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) Phe_AUGlipid
Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) Phe_P0
Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) Phe_AUGprot
Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) Tryp_G0
Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) Tryp_AUCgluc
Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) Tryp_L0
Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) Tryp_AUClipid
Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) Tryp_P0
Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) Tryp_AUCprot
Basal levels at glucose oral load day: Formate_1 (a.u) Formate_G0
Postpradial levels at lipids oral load day: Formate_1 (a.u) Formate_AUCgluc
Basal levels at glucose proteins oral load day: Formate_1 (a.u) Formate_L0
Postpradial levels at glucose oral load day: Formate_1 (a.u) Formate_AUClipid
Basal levels at lipids oral load day: Formate_1 (a.u) Formate_P0
Postpradial levels at porteins oral load day: Formate_1 (a.u) Formate_AUCprot> kbl(d.f_final, digits = c(rep(4, 12), 0)) %>%
+ kable_classic_2() %>%
+ add_header_above(c(` ` = 1, `9` = 2, `8` = 2, `9` = 2, `8` = 2, `10` = 2, `9` = 2,
+ ` ` = 1)) %>%
+ add_header_above(c(` ` = 1, `No Obese` = 2, Obese = 2, `No Obese` = 2, Obese = 2,
+ `No Obese` = 2, Obese = 2, ` ` = 1)) %>%
+ add_header_above(c(` ` = 1, `Control Females` = 4, PCOS = 4, `Control Males` = 4,
+ ` ` = 1))|
Control Females
|
PCOS
|
Control Males
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
No Obese
|
Obese
|
No Obese
|
Obese
|
No Obese
|
Obese
|
||||||||
|
9
|
8
|
9
|
8
|
10
|
9
|
||||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | variable Code | |
| Mean value (a.u) 2-Oxoisocaproic acid_2 | 0.0204 | 0.0183 | 0.0428 | 0.0101 | 0.0358 | 0.0144 | 0.0593 | 0.0087 | 0.0640 | 0.0076 | 0.0597 | 0.0068 | Oxoisocaproic_mean |
| Mean value (a.u) Leucine_1 | 0.1216 | 0.0250 | 0.1338 | 0.0349 | 0.1377 | 0.0200 | 0.1703 | 0.0141 | 0.1981 | 0.0173 | 0.1878 | 0.0226 | Leu_mean |
| Mean value (a.u) Isoleucine_1 | 0.0358 | 0.0065 | 0.0402 | 0.0121 | 0.0336 | 0.0048 | 0.0555 | 0.0052 | 0.0534 | 0.0080 | 0.0519 | 0.0074 | Isoleu_mean |
| Mean value (a.u) L-Valine_1 | 0.1063 | 0.0332 | 0.1409 | 0.0350 | 0.1234 | 0.0315 | 0.1915 | 0.0136 | 0.1979 | 0.0205 | 0.1830 | 0.0213 | Valine_mean |
| Mean value (a.u) Isobutyric acid_1 | 0.0260 | 0.0087 | 0.0175 | 0.0043 | 0.0224 | 0.0070 | 0.0192 | 0.0044 | 0.0212 | 0.0032 | 0.021 | 0.007 | Isobutyric_mean |
| Mean value (a.u) 2-oxoisovaleric acid_1 | 0.0067 | 0.0071 | 0.0169 | 0.0043 | 0.0121 | 0.0067 | 0.0240 | 0.0028 | 0.0212 | 0.0020 | 0.0207 | 0.0024 | Oxoisovaleric_mean |
| Mean value (a.u) 3-Hydroxybutyric acid_1 | 0.0547 | 0.0263 | 0.0488 | 0.0212 | 0.0414 | 0.0206 | 0.0601 | 0.0204 | 0.1003 | 0.0787 | 0.0540 | 0.0305 | OHbutyric_mean |
| Mean value (a.u) Lactate_1 | 1.0700 | 0.2641 | 1.1345 | 0.4346 | 0.9779 | 0.1789 | 1.3403 | 0.4347 | 0.8914 | 0.2428 | 1.1284 | 0.3531 | Lactate_mean |
| Mean value (a.u) Alanine_1 | 0.2493 | 0.0477 | 0.2649 | 0.0575 | 0.2931 | 0.0507 | 0.3525 | 0.0545 | 0.2380 | 0.0557 | 0.2902 | 0.0622 | Alanine_mean |
| Mean value (a.u) Acetate_1 | 0.3652 | 0.0997 | 0.0620 | 0.0364 | 0.3065 | 0.0976 | 0.1531 | 0.0158 | 0.1682 | 0.0269 | 0.1771 | 0.0766 | Acetate_mean |
| Mean value (a.u) N-Ac-Glycoprotein_signals_1 | 0.0576 | 0.0111 | 0.0412 | 0.0082 | 0.0554 | 0.0062 | 0.0645 | 0.0151 | 0.0573 | 0.0129 | 0.0513 | 0.0104 | Glycoprot_mean |
| Mean value (a.u) Acetone_1 | 0.0105 | 0.0032 | 0.023 | 0.003 | 0.0117 | 0.0023 | 0.0307 | 0.0053 | 0.0187 | 0.0026 | 0.0223 | 0.0041 | Acetone_mean |
| Mean value (a.u) L-Glutamic acid_1 | 0.0454 | 0.0035 | 0.0436 | 0.0167 | 0.0453 | 0.0087 | 0.0506 | 0.0062 | 0.0457 | 0.0076 | 0.0524 | 0.0099 | Gluacid_mean |
| Mean value (a.u) Pyruvate_1 | 0.0068 | 0.0032 | 0.0209 | 0.0106 | 0.0125 | 0.0057 | 0.0305 | 0.0156 | 0.0137 | 0.0063 | 0.0180 | 0.0055 | Pyruvate_mean |
| Mean value (a.u) Pyroglutamic acid_1 | 0.0350 | 0.0103 | 0.0157 | 0.0036 | 0.0230 | 0.0149 | 0.0148 | 0.0043 | 0.0254 | 0.0127 | 0.0154 | 0.0050 | Pyroglu_mean |
| Mean value (a.u) L-Glutamine_1 | 0.1226 | 0.0266 | 0.1330 | 0.0252 | 0.1514 | 0.0143 | 0.1683 | 0.0136 | 0.1568 | 0.0118 | 0.1516 | 0.0240 | Gln_mean |
| Mean value (a.u) Citrate_2 | 0.0249 | 0.0053 | 0.0202 | 0.0070 | 0.0252 | 0.0048 | 0.0267 | 0.0046 | 0.0242 | 0.0032 | 0.0194 | 0.0022 | Citrate_mean |
| Mean value (a.u) L-Asparagine_4 | 0.0071 | 0.0006 | 0.0063 | 0.0016 | 0.0081 | 0.0016 | 0.0073 | 0.0014 | 0.0080 | 0.0014 | 0.0070 | 0.0011 | Asn_mean |
| Mean value (a.u) Creatinine_1 | 0.0463 | 0.0062 | 0.0399 | 0.0073 | 0.0460 | 0.0082 | 0.0659 | 0.0281 | 0.0627 | 0.0066 | 0.0523 | 0.0093 | Creatinine_mean |
| Mean value (a.u) Creatine_1 | 0.0292 | 0.0106 | 0.0325 | 0.0107 | 0.0236 | 0.0113 | 0.0386 | 0.0072 | 0.0214 | 0.0080 | 0.0279 | 0.0119 | Creatine_mean |
| Mean value (a.u) Lysine_1 | 0.0150 | 0.0171 | 0.0523 | 0.0131 | 0.0300 | 0.0151 | 0.0619 | 0.0085 | 0.0540 | 0.0088 | 0.0499 | 0.0088 | Lysine_mean |
| Mean value (a.u) Ornithine_1 | 0.0116 | 0.0053 | 0.0193 | 0.0043 | 0.0158 | 0.0060 | 0.0232 | 0.0030 | 0.0215 | 0.0054 | 0.0224 | 0.0061 | Ornithine_mean |
| Mean value (a.u) Choline_1 | 0.0290 | 0.0049 | 0.0264 | 0.0062 | 0.0306 | 0.0090 | 0.0317 | 0.0042 | 0.0302 | 0.0092 | 0.0256 | 0.0085 | Choline_mean |
| Mean value (a.u) L-Carnitine_1 | 0.0934 | 0.0183 | 0.0615 | 0.0107 | 0.0780 | 0.0206 | 0.0846 | 0.0108 | 0.0954 | 0.0093 | 0.0810 | 0.0188 | Carnitine_mean |
| Mean value (a.u) Betaine_1 | 0.0810 | 0.0265 | 0.0570 | 0.0129 | 0.0830 | 0.0247 | 0.0676 | 0.0193 | 0.0773 | 0.0114 | 0.0629 | 0.0213 | Betaine_mean |
| Mean value (a.u) Glycine_1 | 0.0781 | 0.0236 | 0.0836 | 0.0226 | 0.1061 | 0.0195 | 0.0936 | 0.0190 | 0.097 | 0.010 | 0.0940 | 0.0257 | Glycine_mean |
| Mean value (a.u) L-Threonine_1 | 0.0202 | 0.0074 | 0.0234 | 0.0107 | 0.0239 | 0.0094 | 0.0302 | 0.0051 | 0.0237 | 0.0054 | 0.0209 | 0.0066 | Threonine_mean |
| Mean value (a.u) Glycerol_2 | 0.0144 | 0.0097 | 0.0272 | 0.0070 | 0.0217 | 0.0083 | 0.0302 | 0.0076 | 0.0188 | 0.0039 | 0.0189 | 0.0069 | Glycerol_mean |
| Mean value (a.u) L-Serine_1 | 0.0266 | 0.0046 | 0.0238 | 0.0080 | 0.0293 | 0.0040 | 0.0231 | 0.0059 | 0.0225 | 0.0047 | 0.0226 | 0.0055 | Serine_mean |
| Mean value (a.u) L-Proline_3 | 0.0246 | 0.0041 | 0.0226 | 0.0102 | 0.0233 | 0.0055 | 0.0280 | 0.0026 | 0.0263 | 0.0033 | 0.0236 | 0.0041 | Proline_mean |
| Mean value (a.u) beta-Glucose_1 | 0.1744 | 0.0393 | 0.2288 | 0.0399 | 0.2202 | 0.0442 | 0.2874 | 0.0186 | 0.2669 | 0.0238 | 0.2649 | 0.0312 | BGlucose_mean |
| Mean value (a.u) D-Glucose_2 | 0.2627 | 0.0663 | 0.3342 | 0.0608 | 0.3166 | 0.0606 | 0.4178 | 0.0290 | 0.4015 | 0.0241 | 0.3862 | 0.0508 | DGlucose_mean |
| Mean value (a.u) 1-Methylhistidine_1 | 0.0053 | 0.0054 | 0.0135 | 0.0032 | 0.0099 | 0.0055 | 0.0159 | 0.0027 | 0.0157 | 0.0028 | 0.015 | 0.004 | Methys_mean |
| Mean value (a.u) Tyrosine_1 | 0.0274 | 0.0062 | 0.0325 | 0.0088 | 0.0317 | 0.0067 | 0.0402 | 0.0058 | 0.0336 | 0.0065 | 0.0358 | 0.0051 | Tyrosine_mean |
| Mean value (a.u) L-Phenylalanine_2 | 0.0306 | 0.0039 | 0.0293 | 0.0058 | 0.0322 | 0.0043 | 0.0359 | 0.0021 | 0.0352 | 0.0048 | 0.0359 | 0.0054 | Phe_mean |
| Mean value (a.u) L-Tryptophan_4 | 0.0123 | 0.0028 | 0.0155 | 0.0025 | 0.0147 | 0.0026 | 0.0158 | 0.0021 | 0.0167 | 0.0027 | 0.0168 | 0.0018 | Tryp_mean |
| Mean value (a.u) Formate_1 | 0.0191 | 0.0060 | 0.0124 | 0.0018 | 0.0104 | 0.0051 | 0.0163 | 0.0023 | 0.0105 | 0.0009 | 0.0131 | 0.0014 | Formate_mean |
| Basal levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) | 0.0216 | 0.0188 | 0.0418 | 0.0100 | 0.0345 | 0.0125 | 0.0555 | 0.0131 | 0.0635 | 0.0097 | 0.0601 | 0.0077 | Oxoisocaproic_G0 |
| Postpradial levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) | -0.0029 | 0.0036 | -0.0027 | 0.0064 | -0.0024 | 0.0067 | -0.0070 | 0.0113 | -0.0057 | 0.0043 | -0.0085 | 0.0065 | Oxoisocap_AUCgluc |
| Basal levels at glucose proteins oral load day: 2-Oxoisocaproic acid_2 (a.u) | 0.0194 | 0.0160 | 0.0449 | 0.0139 | 0.0368 | 0.0194 | 0.0596 | 0.0104 | 0.0653 | 0.0138 | 0.0595 | 0.0109 | Oxoisocaproic_L0 |
| Postpradial levels at glucose oral load day: 2-Oxoisocaproic acid_2 (a.u) | -0.0021 | 0.0052 | -0.0044 | 0.0105 | -0.0053 | 0.0080 | -0.0036 | 0.0093 | -0.0014 | 0.0099 | -0.0012 | 0.0112 | Oxoisocap_AUClipid |
| Basal levels at lipids oral load day: 2-Oxoisocaproic acid_2 (a.u) | 0.0203 | 0.0216 | 0.042 | 0.012 | 0.0360 | 0.0136 | 0.0629 | 0.0109 | 0.0632 | 0.0101 | 0.0596 | 0.0089 | Oxoisocaproic_P0 |
| Postpradial levels at porteins oral load day: 2-Oxoisocaproic acid_2 (a.u) | -0.0035 | 0.0058 | 0.0136 | 0.0129 | -0.0004 | 0.0066 | 0.0068 | 0.0153 | 0.0098 | 0.0160 | 0.0091 | 0.0089 | Oxoisocap_AUCprot |
| Basal levels at glucose oral load day: Leucine_1 (a.u) | 0.1194 | 0.0220 | 0.1422 | 0.0606 | 0.1420 | 0.0273 | 0.1569 | 0.0177 | 0.1885 | 0.0267 | 0.1729 | 0.0280 | Leu_G0 |
| Postpradial levels at lipids oral load day: Leucine_1 (a.u) | -0.0205 | 0.0124 | -0.0305 | 0.0217 | -0.0311 | 0.0111 | -0.0191 | 0.0190 | -0.0366 | 0.0116 | -0.0264 | 0.0135 | Leu_AUCgluc |
| Basal levels at glucose proteins oral load day: Leucine_1 (a.u) | 0.1199 | 0.0378 | 0.1305 | 0.0271 | 0.1358 | 0.0234 | 0.1776 | 0.0162 | 0.208 | 0.024 | 0.1922 | 0.0241 | Leu_L0 |
| Postpradial levels at glucose oral load day: Leucine_1 (a.u) | -0.0082 | 0.0220 | -0.0076 | 0.0157 | -0.0107 | 0.0132 | -0.0062 | 0.0058 | -0.0226 | 0.0156 | -0.0214 | 0.0172 | Leu_AUClipid |
| Basal levels at lipids oral load day: Leucine_1 (a.u) | 0.1255 | 0.0281 | 0.1289 | 0.0299 | 0.1354 | 0.0266 | 0.1766 | 0.0260 | 0.1983 | 0.0282 | 0.1985 | 0.0397 | Leu_P0 |
| Postpradial levels at porteins oral load day: Leucine_1 (a.u) | 0.1195 | 0.0381 | 0.1554 | 0.0428 | 0.0993 | 0.0618 | 0.1415 | 0.0573 | 0.1859 | 0.0738 | 0.1205 | 0.0331 | Leu_AUCprot |
| Basal levels at glucose oral load day: Isoleucine_1 (a.u) | 0.0344 | 0.0071 | 0.0406 | 0.0228 | 0.0330 | 0.0093 | 0.0520 | 0.0074 | 0.0514 | 0.0080 | 0.0446 | 0.0096 | Isoleu_G0 |
| Postpradial levels at lipids oral load day: Isoleucine_1 (a.u) | -0.0088 | 0.0037 | -0.0124 | 0.0086 | -0.0073 | 0.0044 | -0.0094 | 0.0096 | -0.0128 | 0.0058 | -0.0089 | 0.0076 | Isoleu_AUGgluc |
| Basal levels at glucose proteins oral load day: Isoleucine_1 (a.u) | 0.0374 | 0.0095 | 0.0407 | 0.0116 | 0.0310 | 0.0068 | 0.0542 | 0.0100 | 0.0538 | 0.0100 | 0.0533 | 0.0111 | Isoleu_L0 |
| Postpradial levels at glucose oral load day: Isoleucine_1 (a.u) | -0.0049 | 0.0046 | -0.0055 | 0.0082 | -0.0005 | 0.0049 | -0.0021 | 0.0067 | -0.0036 | 0.0041 | -0.0063 | 0.0094 | Isoleu_AUGlipid |
| Basal levels at lipids oral load day: Isoleucine_1 (a.u) | 0.0357 | 0.0096 | 0.0391 | 0.0077 | 0.0367 | 0.0084 | 0.0603 | 0.0081 | 0.0550 | 0.0125 | 0.0577 | 0.0119 | Isoleu_P0 |
| Postpradial levels at porteins oral load day: Isoleucine_1 (a.u) | 0.0432 | 0.0097 | 0.0562 | 0.0121 | 0.0381 | 0.0176 | 0.0471 | 0.0261 | 0.0687 | 0.0216 | 0.0453 | 0.0130 | Isoleu_AUGprot |
| Basal levels at glucose oral load day: L-Valine_1 (a.u) | 0.1095 | 0.0438 | 0.1424 | 0.0484 | 0.1286 | 0.0349 | 0.1893 | 0.0304 | 0.1998 | 0.0317 | 0.1712 | 0.0119 | Valine_G0 |
| Postpradial levels at lipids oral load day: L-Valine_1 (a.u) | -0.0220 | 0.0117 | -0.0212 | 0.0132 | -0.0190 | 0.0153 | -0.0213 | 0.0219 | -0.0306 | 0.0204 | -0.0172 | 0.0127 | Valine_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Valine_1 (a.u) | 0.0957 | 0.0300 | 0.1406 | 0.0347 | 0.1199 | 0.0359 | 0.1927 | 0.0213 | 0.1979 | 0.0277 | 0.1879 | 0.0331 | Valine_L0 |
| Postpradial levels at glucose oral load day: L-Valine_1 (a.u) | -0.0073 | 0.0049 | -0.0066 | 0.0130 | -0.0086 | 0.0078 | -0.0044 | 0.0109 | -0.0127 | 0.0152 | -0.0188 | 0.0222 | Valine_AUGlipid |
| Basal levels at lipids oral load day: L-Valine_1 (a.u) | 0.1136 | 0.0351 | 0.1398 | 0.0330 | 0.1215 | 0.0332 | 0.1927 | 0.0232 | 0.1962 | 0.0224 | 0.1896 | 0.0312 | Valine_P0 |
| Postpradial levels at porteins oral load day: L-Valine_1 (a.u) | 0.0898 | 0.0261 | 0.1155 | 0.0259 | 0.0693 | 0.0282 | 0.0999 | 0.0452 | 0.1315 | 0.0381 | 0.0856 | 0.0211 | Valine_AUGprot |
| Basal levels at glucose oral load day: Isobutyric acid_1 (a.u) | 0.0285 | 0.0134 | 0.0179 | 0.0058 | 0.0240 | 0.0104 | 0.0185 | 0.0088 | 0.0220 | 0.0074 | 0.0222 | 0.0060 | Isobutyric_G0 |
| Postpradial levels at lipids oral load day: Isobutyric acid_1 (a.u) | -0.0057 | 0.0097 | -0.0015 | 0.0043 | -0.0012 | 0.0052 | -0.0015 | 0.0032 | -0.0009 | 0.0058 | -0.0012 | 0.0048 | Isobutyric_AUGgluc |
| Basal levels at glucose proteins oral load day: Isobutyric acid_1 (a.u) | 0.021 | 0.008 | 0.0162 | 0.0049 | 0.0207 | 0.0092 | 0.0195 | 0.0066 | 0.0212 | 0.0039 | 0.0216 | 0.0075 | Isobutyric_L0 |
| Postpradial levels at glucose oral load day: Isobutyric acid_1 (a.u) | -0.0023 | 0.0069 | -0.0007 | 0.0046 | -0.0041 | 0.0089 | -0.0044 | 0.0042 | -0.0032 | 0.0024 | -0.0035 | 0.0062 | Isobutyric_AUGlipid |
| Basal levels at lipids oral load day: Isobutyric acid_1 (a.u) | 0.0282 | 0.0143 | 0.0183 | 0.0031 | 0.0227 | 0.0080 | 0.0195 | 0.0048 | 0.0206 | 0.0068 | 0.0195 | 0.0101 | Isobutyric_P0 |
| Postpradial levels at porteins oral load day: Isobutyric acid_1 (a.u) | 0.0069 | 0.0117 | 0.0063 | 0.0042 | 0.0067 | 0.0110 | 0.0064 | 0.0069 | 0.0105 | 0.0077 | 0.0094 | 0.0051 | Isobutyric_AUGprot |
| Basal levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) | 0.0077 | 0.0093 | 0.0162 | 0.0051 | 0.0115 | 0.0066 | 0.0219 | 0.0042 | 0.0236 | 0.0044 | 0.0210 | 0.0034 | Oxoisovaleric_G0 |
| Postpradial levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) | -0.0013 | 0.0033 | 0.0006 | 0.0031 | 0.0006 | 0.0035 | 0.0014 | 0.0037 | -0.0019 | 0.0035 | 0.0005 | 0.0038 | Oxoisovaleric_AUGgluc |
| Basal levels at glucose proteins oral load day: 2-oxoisovaleric acid_1 (a.u) | 0.0041 | 0.0059 | 0.0172 | 0.0051 | 0.0126 | 0.0082 | 0.0258 | 0.0046 | 0.0207 | 0.0050 | 0.0208 | 0.0033 | Oxoisovaleric_L0 |
| Postpradial levels at glucose oral load day: 2-oxoisovaleric acid_1 (a.u) | 0.0011 | 0.0010 | 0.0003 | 0.0035 | -0.0026 | 0.0053 | -0.0009 | 0.0035 | 0.0012 | 0.0049 | 0.0002 | 0.0023 | Oxoisovaleric_AUGlipid |
| Basal levels at lipids oral load day: 2-oxoisovaleric acid_1 (a.u) | 0.0084 | 0.0080 | 0.0171 | 0.0045 | 0.0121 | 0.0074 | 0.0243 | 0.0058 | 0.0192 | 0.0043 | 0.0204 | 0.0041 | Oxoisovaleric_P0 |
| Postpradial levels at porteins oral load day: 2-oxoisovaleric acid_1 (a.u) | -0.0015 | 0.0034 | -0.0001 | 0.0024 | -0.0025 | 0.0041 | -0.0011 | 0.0058 | 0.0013 | 0.0033 | -0.0002 | 0.0027 | Oxoisovaleric_AUGprot |
| Basal levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) | 0.0578 | 0.0448 | 0.0444 | 0.0208 | 0.0494 | 0.0239 | 0.0459 | 0.0181 | 0.0775 | 0.0456 | 0.0527 | 0.0465 | OHbutyric_G0 |
| Postpradial levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) | -0.0336 | 0.0329 | -0.0215 | 0.0116 | -0.0241 | 0.0172 | -0.0167 | 0.0128 | -0.0418 | 0.0337 | -0.0245 | 0.0338 | OHbutyric_AUGgluc |
| Basal levels at glucose proteins oral load day: 3-Hydroxybutyric acid_1 (a.u) | 0.0454 | 0.0205 | 0.0437 | 0.0294 | 0.0292 | 0.0118 | 0.0669 | 0.0510 | 0.1278 | 0.1949 | 0.0446 | 0.0209 | OHbutyric_L0 |
| Postpradial levels at glucose oral load day: 3-Hydroxybutyric acid_1 (a.u) | 0.0756 | 0.0693 | 0.0574 | 0.0402 | 0.0768 | 0.0661 | 0.0616 | 0.0466 | 0.0227 | 0.0581 | 0.0260 | 0.0301 | OHbutyric_AUGlipid |
| Basal levels at lipids oral load day: 3-Hydroxybutyric acid_1 (a.u) | 0.0608 | 0.0543 | 0.0583 | 0.0333 | 0.0455 | 0.0414 | 0.0675 | 0.0194 | 0.0956 | 0.0541 | 0.0644 | 0.0573 | OHbutyric_P0 |
| Postpradial levels at porteins oral load day: 3-Hydroxybutyric acid_1 (a.u) | -0.0122 | 0.0314 | -0.0159 | 0.0147 | -0.0035 | 0.0257 | -0.0148 | 0.0133 | -0.0213 | 0.0358 | -0.0154 | 0.0312 | OHbutyric_AUGprot |
| Basal levels at glucose oral load day: Lactate_1 (a.u) | 1.1376 | 0.4693 | 1.1283 | 0.4463 | 1.0027 | 0.3110 | 1.2590 | 0.4811 | 0.8826 | 0.2112 | 1.0779 | 0.2999 | Lactate_G0 |
| Postpradial levels at lipids oral load day: Lactate_1 (a.u) | 0.2059 | 0.2705 | 0.2565 | 0.2802 | 0.2856 | 0.1823 | 0.2964 | 0.2377 | 0.2752 | 0.2112 | 0.1720 | 0.1334 | Lactate_AUGgluc |
| Basal levels at glucose proteins oral load day: Lactate_1 (a.u) | 1.1333 | 0.6387 | 1.0738 | 0.6222 | 0.9956 | 0.2010 | 1.4677 | 0.6231 | 0.9666 | 0.4722 | 1.0979 | 0.4172 | Lactate_L0 |
| Postpradial levels at glucose oral load day: Lactate_1 (a.u) | -0.2396 | 0.4802 | -0.1407 | 0.3260 | -0.0544 | 0.2198 | -0.2554 | 0.2542 | -0.0916 | 0.3599 | -0.2321 | 0.1755 | Lactate_AUGlipid |
| Basal levels at lipids oral load day: Lactate_1 (a.u) | 0.9390 | 0.1639 | 1.2016 | 0.4422 | 0.9355 | 0.3125 | 1.2942 | 0.4740 | 0.8248 | 0.1733 | 1.2094 | 0.4606 | Lactate_P0 |
| Postpradial levels at porteins oral load day: Lactate_1 (a.u) | 0.1209 | 0.2340 | -0.0425 | 0.2126 | 0.0115 | 0.2083 | -0.0511 | 0.3269 | 0.0645 | 0.1087 | -0.1341 | 0.2079 | Lactate_AUGprot |
| Basal levels at glucose oral load day: Alanine_1 (a.u) | 0.2441 | 0.0478 | 0.2727 | 0.0672 | 0.2682 | 0.0589 | 0.3430 | 0.0606 | 0.2386 | 0.0482 | 0.2793 | 0.0663 | Alanine_G0 |
| Postpradial levels at lipids oral load day: Alanine_1 (a.u) | 0.0119 | 0.0278 | 0.0052 | 0.0315 | 0.0041 | 0.0258 | 0.0076 | 0.0368 | 0.0050 | 0.0167 | 0.0108 | 0.0303 | Alanine_AUGgluc |
| Basal levels at glucose proteins oral load day: Alanine_1 (a.u) | 0.2497 | 0.0529 | 0.2551 | 0.0636 | 0.3088 | 0.0678 | 0.3528 | 0.0923 | 0.2432 | 0.0689 | 0.2885 | 0.0814 | Alanine_L0 |
| Postpradial levels at glucose oral load day: Alanine_1 (a.u) | -0.0324 | 0.0317 | -0.0165 | 0.0203 | -0.0365 | 0.0450 | -0.0158 | 0.0422 | -0.0228 | 0.0299 | -0.0281 | 0.0197 | Alanine_AUGlipid |
| Basal levels at lipids oral load day: Alanine_1 (a.u) | 0.2541 | 0.0805 | 0.2670 | 0.0713 | 0.3022 | 0.0591 | 0.3618 | 0.0743 | 0.2322 | 0.0613 | 0.3027 | 0.0871 | Alanine_P0 |
| Postpradial levels at porteins oral load day: Alanine_1 (a.u) | 0.0548 | 0.0322 | 0.0833 | 0.0473 | 0.0427 | 0.0510 | 0.0555 | 0.0772 | 0.0625 | 0.0352 | 0.0572 | 0.0268 | Alanine_AUGprot |
| Basal levels at glucose oral load day: Acetate_1 (a.u) | 0.3778 | 0.1204 | 0.0553 | 0.0344 | 0.2869 | 0.0604 | 0.1499 | 0.0231 | 0.1712 | 0.0289 | 0.1749 | 0.0806 | Acetate_G0 |
| Postpradial levels at lipids oral load day: Acetate_1 (a.u) | -0.0108 | 0.0240 | -0.0058 | 0.0073 | 0.0162 | 0.0408 | -0.0052 | 0.0137 | -0.0071 | 0.0222 | -0.0019 | 0.0103 | Acetate_AUGgluc |
| Basal levels at glucose proteins oral load day: Acetate_1 (a.u) | 0.3548 | 0.0936 | 0.0606 | 0.0429 | 0.3107 | 0.1150 | 0.1519 | 0.0156 | 0.1704 | 0.0403 | 0.1717 | 0.0744 | Acetate_L0 |
| Postpradial levels at glucose oral load day: Acetate_1 (a.u) | -0.0151 | 0.0747 | -0.0025 | 0.0044 | 0.0017 | 0.0286 | -0.0031 | 0.0068 | -0.0121 | 0.0102 | 0.0040 | 0.0139 | Acetate_AUGlipid |
| Basal levels at lipids oral load day: Acetate_1 (a.u) | 0.3629 | 0.1047 | 0.0700 | 0.0342 | 0.3219 | 0.1326 | 0.1575 | 0.0220 | 0.1628 | 0.0330 | 0.1848 | 0.0817 | Acetate_P0 |
| Postpradial levels at porteins oral load day: Acetate_1 (a.u) | 0.0148 | 0.0267 | -0.018 | 0.006 | -0.0242 | 0.0568 | -0.0187 | 0.0123 | -0.0142 | 0.0191 | 0.0038 | 0.0330 | Acetate_AUGprot |
| Basal levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) | 0.0562 | 0.0111 | 0.0385 | 0.0088 | 0.0541 | 0.0083 | 0.0603 | 0.0237 | 0.0564 | 0.0147 | 0.0482 | 0.0091 | Glycoprot_G0 |
| Postpradial levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) | -0.0023 | 0.0041 | -0.0009 | 0.0037 | -0.0006 | 0.0048 | 0.0045 | 0.0108 | -0.0018 | 0.0030 | 0.0012 | 0.0027 | Glycoprot_AUGgluc |
| Basal levels at glucose proteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) | 0.0583 | 0.0119 | 0.0413 | 0.0070 | 0.0552 | 0.0048 | 0.0660 | 0.0111 | 0.0583 | 0.0129 | 0.0525 | 0.0116 | Glycoprot_L0 |
| Postpradial levels at glucose oral load day: N-Ac-Glycoprotein_signals_1 (a.u) | -0.0053 | 0.0062 | 0.0004 | 0.0064 | -0.0025 | 0.0021 | -0.0013 | 0.0047 | -0.0017 | 0.0041 | -0.0028 | 0.0045 | Glycoprot_AUGlipid |
| Basal levels at lipids oral load day: N-Ac-Glycoprotein_signals_1 (a.u) | 0.0584 | 0.0109 | 0.0437 | 0.0106 | 0.0567 | 0.0095 | 0.0676 | 0.0133 | 0.0570 | 0.0123 | 0.0533 | 0.0110 | Glycoprot_P0 |
| Postpradial levels at porteins oral load day: N-Ac-Glycoprotein_signals_1 (a.u) | -0.0027 | 0.0037 | -0.0021 | 0.0019 | -0.0056 | 0.0056 | -0.0026 | 0.0051 | -0.0028 | 0.0025 | -0.0027 | 0.0033 | Glycoprot_AUGprot |
| Basal levels at glucose oral load day: Acetone_1 (a.u) | 0.0115 | 0.0087 | 0.0274 | 0.0053 | 0.0122 | 0.0029 | 0.0275 | 0.0050 | 0.0202 | 0.0044 | 0.0214 | 0.0047 | Acetone_G0 |
| Postpradial levels at lipids oral load day: Acetone_1 (a.u) | -0.0012 | 0.0046 | -0.0051 | 0.0027 | 0.0002 | 0.0015 | 0.0001 | 0.0044 | -0.0016 | 0.0031 | -0.0023 | 0.0051 | Acetone_AUGgluc |
| Basal levels at glucose proteins oral load day: Acetone_1 (a.u) | 0.0103 | 0.0020 | 0.0199 | 0.0016 | 0.0124 | 0.0020 | 0.0334 | 0.0113 | 0.0167 | 0.0040 | 0.0223 | 0.0067 | Acetone_L0 |
| Postpradial levels at glucose oral load day: Acetone_1 (a.u) | 0.0004 | 0.0051 | 0.0043 | 0.0044 | -0.0016 | 0.0026 | 0.0042 | 0.0055 | 0.0062 | 0.0043 | 0.0037 | 0.0051 | Acetone_AUGlipid |
| Basal levels at lipids oral load day: Acetone_1 (a.u) | 0.0096 | 0.0032 | 0.0216 | 0.0054 | 0.0108 | 0.0029 | 0.0315 | 0.0081 | 0.0193 | 0.0049 | 0.0229 | 0.0073 | Acetone_P0 |
| Postpradial levels at porteins oral load day: Acetone_1 (a.u) | 8e-04 | 3e-03 | 0.0016 | 0.0032 | 0.0013 | 0.0029 | 0.0017 | 0.0066 | 0.0042 | 0.0065 | 0.0012 | 0.0060 | Acetone_AUGprot |
| Basal levels at glucose oral load day: L-Glutamic acid_1 (a.u) | 0.0486 | 0.0061 | 0.0477 | 0.0196 | 0.0461 | 0.0083 | 0.0446 | 0.0100 | 0.0446 | 0.0108 | 0.0498 | 0.0076 | Gluacid_G0 |
| Postpradial levels at lipids oral load day: L-Glutamic acid_1 (a.u) | -0.0034 | 0.0057 | -0.0052 | 0.0044 | -0.0034 | 0.0040 | 0.0006 | 0.0054 | -0.0019 | 0.0046 | 0.0006 | 0.0043 | Gluacid_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Glutamic acid_1 (a.u) | 0.0428 | 0.0043 | 0.0410 | 0.0147 | 0.0439 | 0.0115 | 0.0551 | 0.0042 | 0.0462 | 0.0067 | 0.0534 | 0.0126 | Gluacid_L0 |
| Postpradial levels at glucose oral load day: L-Glutamic acid_1 (a.u) | -0.0032 | 0.0038 | -0.0013 | 0.0034 | -0.0046 | 0.0052 | -0.0069 | 0.0042 | -0.0027 | 0.0043 | -0.0054 | 0.0065 | Gluacid_AUGlipid |
| Basal levels at lipids oral load day: L-Glutamic acid_1 (a.u) | 0.0447 | 0.0064 | 0.042 | 0.017 | 0.0456 | 0.0088 | 0.0521 | 0.0106 | 0.0461 | 0.0089 | 0.0543 | 0.0100 | Gluacid_P0 |
| Postpradial levels at porteins oral load day: L-Glutamic acid_1 (a.u) | 0.0172 | 0.0072 | 0.0189 | 0.0056 | 0.0105 | 0.0057 | 0.016 | 0.014 | 0.0201 | 0.0079 | 0.0140 | 0.0076 | Gluacid_AUGprot |
| Basal levels at glucose oral load day: Pyruvate_1 (a.u) | 0.0061 | 0.0023 | 0.0250 | 0.0129 | 0.0118 | 0.0060 | 0.0249 | 0.0177 | 0.0147 | 0.0083 | 0.0215 | 0.0080 | Pyruvate_G0 |
| Postpradial levels at lipids oral load day: Pyruvate_1 (a.u) | 0.0033 | 0.0092 | 0.0068 | 0.0076 | 0.0011 | 0.0042 | 0.0162 | 0.0121 | 0.0094 | 0.0056 | 0.0067 | 0.0045 | Pyruvate_AUGgluc |
| Basal levels at glucose proteins oral load day: Pyruvate_1 (a.u) | 0.0065 | 0.0043 | 0.0182 | 0.0107 | 0.0135 | 0.0068 | 0.0367 | 0.0198 | 0.0157 | 0.0098 | 0.0150 | 0.0078 | Pyruvate_L0 |
| Postpradial levels at glucose oral load day: Pyruvate_1 (a.u) | -0.0008 | 0.0029 | -0.0008 | 0.0075 | -0.0028 | 0.0038 | -0.0045 | 0.0052 | -0.0001 | 0.0072 | -0.0001 | 0.0041 | Pyruvate_AUGlipid |
| Basal levels at lipids oral load day: Pyruvate_1 (a.u) | 0.0076 | 0.0055 | 0.0196 | 0.0125 | 0.0121 | 0.0062 | 0.0298 | 0.0137 | 0.0109 | 0.0052 | 0.0172 | 0.0069 | Pyruvate_P0 |
| Postpradial levels at porteins oral load day: Pyruvate_1 (a.u) | 0.0064 | 0.0028 | 0.0099 | 0.0063 | 0.0027 | 0.0040 | 0.0080 | 0.0131 | 0.0102 | 0.0059 | 0.0083 | 0.0058 | Pyruvate_AUGprot |
| Basal levels at glucose oral load day: Pyroglutamic acid_1 (a.u) | 0.0348 | 0.0094 | 0.0139 | 0.0042 | 0.0241 | 0.0161 | 0.0128 | 0.0048 | 0.0197 | 0.0089 | 0.0142 | 0.0084 | Pyroglu_G0 |
| Postpradial levels at lipids oral load day: Pyroglutamic acid_1 (a.u) | -0.0048 | 0.0065 | -0.0046 | 0.0024 | -0.0042 | 0.0066 | -0.0027 | 0.0031 | -0.0070 | 0.0065 | -0.0042 | 0.0046 | Pyroglu_AUGgluc |
| Basal levels at glucose proteins oral load day: Pyroglutamic acid_1 (a.u) | 0.0354 | 0.0090 | 0.0141 | 0.0061 | 0.0199 | 0.0094 | 0.0150 | 0.0082 | 0.0324 | 0.0326 | 0.0139 | 0.0045 | Pyroglu_L0 |
| Postpradial levels at glucose oral load day: Pyroglutamic acid_1 (a.u) | 0.0117 | 0.0144 | 0.0089 | 0.0092 | 0.0129 | 0.0119 | 0.0108 | 0.0076 | 0.0003 | 0.0102 | 0.0044 | 0.0069 | Pyroglu_AUGlipid |
| Basal levels at lipids oral load day: Pyroglutamic acid_1 (a.u) | 0.0351 | 0.0157 | 0.0191 | 0.0080 | 0.0250 | 0.0192 | 0.0166 | 0.0046 | 0.0242 | 0.0081 | 0.0180 | 0.0104 | Pyroglu_P0 |
| Postpradial levels at porteins oral load day: Pyroglutamic acid_1 (a.u) | -0.0001 | 0.0053 | -0.0061 | 0.0060 | -0.0012 | 0.0043 | -0.0040 | 0.0042 | -0.0051 | 0.0063 | -0.0017 | 0.0066 | Pyroglu_AUGprot |
| Basal levels at glucose oral load day: L-Glutamine_1 (a.u) | 0.1220 | 0.0249 | 0.128 | 0.019 | 0.1526 | 0.0196 | 0.1617 | 0.0238 | 0.1510 | 0.0155 | 0.144 | 0.023 | Gln_G0 |
| Postpradial levels at lipids oral load day: L-Glutamine_1 (a.u) | -0.0012 | 0.0159 | -0.0095 | 0.0093 | -0.0057 | 0.0106 | 0.0019 | 0.0197 | -0.0063 | 0.0125 | -0.0044 | 0.0099 | Gln_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Glutamine_1 (a.u) | 0.1207 | 0.0283 | 0.1277 | 0.0201 | 0.1482 | 0.0208 | 0.1704 | 0.0191 | 0.1591 | 0.0141 | 0.1558 | 0.0245 | Gln_L0 |
| Postpradial levels at glucose oral load day: L-Glutamine_1 (a.u) | 0.0017 | 0.0097 | 0.0102 | 0.0097 | 0.0044 | 0.0129 | 0.0093 | 0.0115 | 0.0017 | 0.0117 | -0.0024 | 0.0084 | Gln_AUGlipid |
| Basal levels at lipids oral load day: L-Glutamine_1 (a.u) | 0.1253 | 0.0339 | 0.1431 | 0.0398 | 0.1535 | 0.0171 | 0.1728 | 0.0133 | 0.1604 | 0.0136 | 0.1549 | 0.0285 | Gln_P0 |
| Postpradial levels at porteins oral load day: L-Glutamine_1 (a.u) | 0.0149 | 0.0114 | 0.0159 | 0.0170 | 0.0171 | 0.0172 | 0.0162 | 0.0181 | 0.0194 | 0.0129 | 0.0125 | 0.0054 | Gln_AUGprot |
| Basal levels at glucose oral load day: Citrate_2 (a.u) | 0.0257 | 0.0062 | 0.0195 | 0.0080 | 0.0249 | 0.0076 | 0.0265 | 0.0047 | 0.0246 | 0.0065 | 0.0195 | 0.0041 | Citrate_G0 |
| Postpradial levels at lipids oral load day: Citrate_2 (a.u) | 0.0047 | 0.0056 | 0.0004 | 0.0044 | 0.0041 | 0.0029 | 0.0022 | 0.0068 | 0.0022 | 0.0044 | 0.0025 | 0.0038 | Citrate_AUGgluc |
| Basal levels at glucose proteins oral load day: Citrate_2 (a.u) | 0.0247 | 0.0079 | 0.0189 | 0.0055 | 0.0249 | 0.0064 | 0.0262 | 0.0060 | 0.0234 | 0.0045 | 0.0187 | 0.0032 | Citrate_L0 |
| Postpradial levels at glucose oral load day: Citrate_2 (a.u) | 0.0037 | 0.0051 | 0.0035 | 0.0044 | 0.0057 | 0.0067 | 0.0064 | 0.0053 | 0.0034 | 0.0049 | 0.0006 | 0.0024 | Citrate_AUGlipid |
| Basal levels at lipids oral load day: Citrate_2 (a.u) | 0.0242 | 0.0056 | 0.0224 | 0.0086 | 0.0258 | 0.0069 | 0.0276 | 0.0073 | 0.0242 | 0.0046 | 0.0200 | 0.0043 | Citrate_P0 |
| Postpradial levels at porteins oral load day: Citrate_2 (a.u) | 0.0008 | 0.0041 | -0.0014 | 0.0037 | 0.0006 | 0.0044 | -2e-04 | 7e-03 | -0.0008 | 0.0032 | -0.0001 | 0.0024 | Citrate_AUGprot |
| Basal levels at glucose oral load day: L-Asparagine_4 (a.u) | 0.0070 | 0.0013 | 0.0059 | 0.0017 | 0.0078 | 0.0017 | 0.0064 | 0.0030 | 0.0071 | 0.0020 | 0.0059 | 0.0022 | Asn_G0 |
| Postpradial levels at lipids oral load day: L-Asparagine_4 (a.u) | 0e+00 | 9e-04 | -0.0002 | 0.0011 | -0.0009 | 0.0015 | 0.0007 | 0.0023 | 0.0000 | 0.0012 | 0.0005 | 0.0014 | Asn_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Asparagine_4 (a.u) | 0.0072 | 0.0021 | 0.0072 | 0.0022 | 0.0085 | 0.0025 | 0.0074 | 0.0017 | 0.0086 | 0.0020 | 0.0076 | 0.0012 | Asn_L0 |
| Postpradial levels at glucose oral load day: L-Asparagine_4 (a.u) | 0.0002 | 0.0022 | -0.0008 | 0.0015 | -2e-04 | 2e-03 | 0.0003 | 0.0017 | -0.0010 | 0.0015 | -0.0006 | 0.0018 | Asn_AUGlipid |
| Basal levels at lipids oral load day: L-Asparagine_4 (a.u) | 7e-03 | 9e-04 | 0.0056 | 0.0022 | 0.0080 | 0.0027 | 0.0080 | 0.0031 | 0.0081 | 0.0014 | 0.0072 | 0.0012 | Asn_P0 |
| Postpradial levels at porteins oral load day: L-Asparagine_4 (a.u) | 0.0023 | 0.0013 | 0.0034 | 0.0009 | 0.002 | 0.003 | 0.0027 | 0.0027 | 0.0026 | 0.0018 | 0.0020 | 0.0012 | Asn_AUGprot |
| Basal levels at glucose oral load day: Creatinine_1 (a.u) | 0.0467 | 0.0062 | 0.0385 | 0.0066 | 0.0427 | 0.0103 | 0.0735 | 0.0749 | 0.0626 | 0.0077 | 0.0496 | 0.0096 | Creatinine_G0 |
| Postpradial levels at lipids oral load day: Creatinine_1 (a.u) | -0.0033 | 0.0046 | -0.0018 | 0.0066 | 0.0028 | 0.0039 | -0.0158 | 0.0518 | -0.0027 | 0.0075 | 0.0004 | 0.0073 | Creatinine_AUGgluc |
| Basal levels at glucose proteins oral load day: Creatinine_1 (a.u) | 0.0445 | 0.0072 | 0.0425 | 0.0085 | 0.0468 | 0.0103 | 0.0523 | 0.0067 | 0.0610 | 0.0098 | 0.0515 | 0.0083 | Creatinine_L0 |
| Postpradial levels at glucose oral load day: Creatinine_1 (a.u) | -0.0018 | 0.0071 | -0.0019 | 0.0037 | -0.0040 | 0.0046 | -0.0019 | 0.0049 | -0.0009 | 0.0089 | -0.0027 | 0.0076 | Creatinine_AUGlipid |
| Basal levels at lipids oral load day: Creatinine_1 (a.u) | 0.0476 | 0.0102 | 0.0390 | 0.0096 | 0.0484 | 0.0128 | 0.0719 | 0.0456 | 0.0644 | 0.0066 | 0.0555 | 0.0133 | Creatinine_P0 |
| Postpradial levels at porteins oral load day: Creatinine_1 (a.u) | -0.0014 | 0.0053 | 0.0021 | 0.0059 | -0.0035 | 0.0101 | -0.0173 | 0.0361 | -0.0044 | 0.0053 | -0.0011 | 0.0112 | Creatinine_AUGprot |
| Basal levels at glucose oral load day: Creatine_1 (a.u) | 0.0311 | 0.0131 | 0.0345 | 0.0172 | 0.0210 | 0.0115 | 0.0362 | 0.0136 | 0.0246 | 0.0099 | 0.0264 | 0.0104 | Creatine_G0 |
| Postpradial levels at lipids oral load day: Creatine_1 (a.u) | -0.0025 | 0.0050 | -0.0014 | 0.0073 | 0.0029 | 0.0054 | 0.0041 | 0.0100 | -0.0006 | 0.0041 | 0.0003 | 0.0044 | Creatine_AUGgluc |
| Basal levels at glucose proteins oral load day: Creatine_1 (a.u) | 0.0265 | 0.0120 | 0.0306 | 0.0091 | 0.0222 | 0.0104 | 0.0394 | 0.0079 | 0.0178 | 0.0079 | 0.0259 | 0.0142 | Creatine_L0 |
| Postpradial levels at glucose oral load day: Creatine_1 (a.u) | -0.0046 | 0.0061 | -0.0015 | 0.0035 | -0.0018 | 0.0035 | -0.0044 | 0.0058 | 0.0016 | 0.0038 | -0.0006 | 0.0056 | Creatine_AUGlipid |
| Basal levels at lipids oral load day: Creatine_1 (a.u) | 0.0298 | 0.0112 | 0.0321 | 0.0082 | 0.0278 | 0.0147 | 0.0403 | 0.0157 | 0.0220 | 0.0086 | 0.0313 | 0.0170 | Creatine_P0 |
| Postpradial levels at porteins oral load day: Creatine_1 (a.u) | 0.0090 | 0.0079 | 0.0147 | 0.0088 | 0.0072 | 0.0056 | 0.0137 | 0.0072 | 0.0126 | 0.0061 | 0.0080 | 0.0066 | Creatine_AUGprot |
| Basal levels at glucose oral load day: Lysine_1 (a.u) | 0.0170 | 0.0199 | 0.0545 | 0.0161 | 0.0330 | 0.0149 | 0.060 | 0.015 | 0.0571 | 0.0118 | 0.0463 | 0.0070 | Lysine_G0 |
| Postpradial levels at lipids oral load day: Lysine_1 (a.u) | -0.0014 | 0.0045 | -0.0107 | 0.0066 | -0.0064 | 0.0062 | -0.001 | 0.014 | -0.0070 | 0.0092 | 0.0011 | 0.0057 | Lysine_AUGgluc |
| Basal levels at glucose proteins oral load day: Lysine_1 (a.u) | 0.0135 | 0.0161 | 0.0529 | 0.0129 | 0.0308 | 0.0176 | 0.0656 | 0.0086 | 0.0532 | 0.0092 | 0.0516 | 0.0102 | Lysine_L0 |
| Postpradial levels at glucose oral load day: Lysine_1 (a.u) | 0.0019 | 0.0058 | -0.0025 | 0.0053 | 0.0005 | 0.0062 | 0.0029 | 0.0046 | 0.0041 | 0.0081 | -0.0026 | 0.0061 | Lysine_AUGlipid |
| Basal levels at lipids oral load day: Lysine_1 (a.u) | 0.0146 | 0.0168 | 0.0493 | 0.0168 | 0.0263 | 0.0176 | 0.0600 | 0.0106 | 0.0520 | 0.0103 | 0.0519 | 0.0159 | Lysine_P0 |
| Postpradial levels at porteins oral load day: Lysine_1 (a.u) | 0.0185 | 0.0131 | 0.0466 | 0.0141 | 0.0270 | 0.0126 | 0.0483 | 0.0160 | 0.0516 | 0.0177 | 0.0338 | 0.0091 | Lysine_AUGprot |
| Basal levels at glucose oral load day: Ornithine_1 (a.u) | 0.0112 | 0.0074 | 0.0186 | 0.0052 | 0.0176 | 0.0058 | 0.0216 | 0.0067 | 0.0208 | 0.0073 | 0.0198 | 0.0050 | Ornithine_G0 |
| Postpradial levels at lipids oral load day: Ornithine_1 (a.u) | -0.0012 | 0.0040 | -0.0017 | 0.0038 | -0.0016 | 0.0028 | -0.0007 | 0.0074 | -0.0026 | 0.0053 | 0.0007 | 0.0025 | Ornithine_AUGgluc |
| Basal levels at glucose proteins oral load day: Ornithine_1 (a.u) | 0.0124 | 0.0043 | 0.0200 | 0.0047 | 0.0145 | 0.0088 | 0.0239 | 0.0071 | 0.0214 | 0.0076 | 0.0226 | 0.0059 | Ornithine_L0 |
| Postpradial levels at glucose oral load day: Ornithine_1 (a.u) | -0.0004 | 0.0038 | -0.0008 | 0.0028 | 6e-04 | 5e-03 | -3e-04 | 4e-03 | 0.0005 | 0.0053 | -0.0030 | 0.0035 | Ornithine_AUGlipid |
| Basal levels at lipids oral load day: Ornithine_1 (a.u) | 0.0111 | 0.0053 | 0.0194 | 0.0064 | 0.0156 | 0.0076 | 0.0240 | 0.0051 | 0.0223 | 0.0054 | 0.0249 | 0.0109 | Ornithine_P0 |
| Postpradial levels at porteins oral load day: Ornithine_1 (a.u) | 0.0010 | 0.0043 | 0.0042 | 0.0043 | 0.0019 | 0.0043 | 0.002 | 0.004 | 0.0048 | 0.0043 | 0.0007 | 0.0077 | Ornithine_AUGprot |
| Basal levels at glucose oral load day: Choline_1 (a.u) | 0.0316 | 0.0060 | 0.0241 | 0.0069 | 0.0313 | 0.0129 | 0.0282 | 0.0054 | 0.0279 | 0.0141 | 0.0266 | 0.0109 | Choline_G0 |
| Postpradial levels at lipids oral load day: Choline_1 (a.u) | 0.0000 | 0.0039 | 0.0001 | 0.0048 | -0.0009 | 0.0064 | 0.0062 | 0.0086 | 0.0016 | 0.0088 | 0.0011 | 0.0115 | Choline_AUGgluc |
| Basal levels at glucose proteins oral load day: Choline_1 (a.u) | 0.0286 | 0.0102 | 0.0258 | 0.0094 | 0.0290 | 0.0095 | 0.0321 | 0.0072 | 0.0297 | 0.0126 | 0.0212 | 0.0100 | Choline_L0 |
| Postpradial levels at glucose oral load day: Choline_1 (a.u) | 0.0019 | 0.0088 | 0.0024 | 0.0065 | 0.0025 | 0.0084 | 0.0023 | 0.0091 | -0.0022 | 0.0068 | 0.0065 | 0.0125 | Choline_AUGlipid |
| Basal levels at lipids oral load day: Choline_1 (a.u) | 0.027 | 0.011 | 0.0297 | 0.0090 | 0.0316 | 0.0110 | 0.035 | 0.010 | 0.0328 | 0.0143 | 0.0290 | 0.0116 | Choline_P0 |
| Postpradial levels at porteins oral load day: Choline_1 (a.u) | 0.0019 | 0.0078 | -0.0028 | 0.0102 | 4e-04 | 6e-03 | -0.0011 | 0.0091 | -0.0028 | 0.0138 | -0.0016 | 0.0074 | Choline_AUGprot |
| Basal levels at glucose oral load day: L-Carnitine_1 (a.u) | 0.0962 | 0.0228 | 0.0582 | 0.0117 | 0.0772 | 0.0282 | 0.0813 | 0.0157 | 0.0991 | 0.0125 | 0.0843 | 0.0243 | Carnitine_G0 |
| Postpradial levels at lipids oral load day: L-Carnitine_1 (a.u) | -0.0039 | 0.0098 | -0.0001 | 0.0087 | 0.0064 | 0.0135 | 0.0055 | 0.0141 | 0.0039 | 0.0114 | -0.0046 | 0.0101 | Carnitine_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Carnitine_1 (a.u) | 0.0881 | 0.0220 | 0.0622 | 0.0128 | 0.0711 | 0.0229 | 0.0823 | 0.0140 | 0.0907 | 0.0141 | 0.0748 | 0.0256 | Carnitine_L0 |
| Postpradial levels at glucose oral load day: L-Carnitine_1 (a.u) | -0.0057 | 0.0168 | 0.006 | 0.005 | 0.0074 | 0.0168 | 0.0034 | 0.0107 | 0.0026 | 0.0120 | 0.0070 | 0.0207 | Carnitine_AUGlipid |
| Basal levels at lipids oral load day: L-Carnitine_1 (a.u) | 0.0960 | 0.0253 | 0.0641 | 0.0137 | 0.0853 | 0.0321 | 0.0900 | 0.0156 | 0.0961 | 0.0149 | 0.0841 | 0.0204 | Carnitine_P0 |
| Postpradial levels at porteins oral load day: L-Carnitine_1 (a.u) | -0.0022 | 0.0179 | 0.0025 | 0.0061 | -0.0081 | 0.0208 | 0.0038 | 0.0113 | -0.0006 | 0.0112 | -0.0034 | 0.0131 | Carnitine_AUGprot |
| Basal levels at glucose oral load day: Betaine_1 (a.u) | 0.0870 | 0.0289 | 0.0573 | 0.0096 | 0.0753 | 0.0291 | 0.0662 | 0.0281 | 0.0777 | 0.0209 | 0.0573 | 0.0167 | Betaine_G0 |
| Postpradial levels at lipids oral load day: Betaine_1 (a.u) | 0.0017 | 0.0089 | -0.0021 | 0.0113 | 0.0024 | 0.0140 | 0.0043 | 0.0133 | -0.0058 | 0.0110 | -0.0046 | 0.0080 | Betaine_AUGgluc |
| Basal levels at glucose proteins oral load day: Betaine_1 (a.u) | 0.0796 | 0.0283 | 0.0585 | 0.0144 | 0.0849 | 0.0355 | 0.0711 | 0.0278 | 0.0715 | 0.0160 | 0.0536 | 0.0188 | Betaine_L0 |
| Postpradial levels at glucose oral load day: Betaine_1 (a.u) | 0.0007 | 0.0139 | 0.0030 | 0.0067 | -0.0083 | 0.0131 | -0.0018 | 0.0153 | -0.0002 | 0.0107 | 0.0014 | 0.0100 | Betaine_AUGlipid |
| Basal levels at lipids oral load day: Betaine_1 (a.u) | 0.0767 | 0.0323 | 0.0553 | 0.0203 | 0.0887 | 0.0285 | 0.0653 | 0.0248 | 0.0828 | 0.0109 | 0.0780 | 0.0441 | Betaine_P0 |
| Postpradial levels at porteins oral load day: Betaine_1 (a.u) | 0.0064 | 0.0128 | 0.0121 | 0.0185 | -0.0039 | 0.0084 | 0.0001 | 0.0094 | 0.0070 | 0.0066 | -0.0008 | 0.0124 | Betaine_AUGprot |
| Basal levels at glucose oral load day: Glycine_1 (a.u) | 0.0738 | 0.0203 | 0.0831 | 0.0186 | 0.1045 | 0.0246 | 0.0921 | 0.0194 | 0.0967 | 0.0141 | 0.0890 | 0.0281 | Glycine_G0 |
| Postpradial levels at lipids oral load day: Glycine_1 (a.u) | -0.0069 | 0.0081 | -0.0070 | 0.0068 | -0.0036 | 0.0032 | -0.0021 | 0.0142 | -0.0068 | 0.0077 | -0.0025 | 0.0110 | Glycine_AUGgluc |
| Basal levels at glucose proteins oral load day: Glycine_1 (a.u) | 0.0786 | 0.0261 | 0.0821 | 0.0245 | 0.1039 | 0.0253 | 0.0928 | 0.0196 | 0.1003 | 0.0142 | 0.0956 | 0.0249 | Glycine_L0 |
| Postpradial levels at glucose oral load day: Glycine_1 (a.u) | -0.0082 | 0.0089 | -0.0020 | 0.0096 | -0.0007 | 0.0174 | -0.0051 | 0.0079 | -0.0013 | 0.0104 | -0.0065 | 0.0067 | Glycine_AUGlipid |
| Basal levels at lipids oral load day: Glycine_1 (a.u) | 0.0819 | 0.0301 | 0.0859 | 0.0303 | 0.1099 | 0.0175 | 0.0958 | 0.0291 | 0.0940 | 0.0101 | 0.0974 | 0.0283 | Glycine_P0 |
| Postpradial levels at porteins oral load day: Glycine_1 (a.u) | 0.0015 | 0.0040 | 0.0029 | 0.0066 | 0.0028 | 0.0116 | 0.0042 | 0.0187 | 0.0049 | 0.0074 | 0.0005 | 0.0038 | Glycine_AUGprot |
| Basal levels at glucose oral load day: L-Threonine_1 (a.u) | 0.0206 | 0.0110 | 0.0238 | 0.0159 | 0.0253 | 0.0123 | 0.0292 | 0.0062 | 0.0245 | 0.0096 | 0.0206 | 0.0079 | Threonine_G0 |
| Postpradial levels at lipids oral load day: L-Threonine_1 (a.u) | -0.0045 | 0.0077 | -0.0024 | 0.0039 | -0.0030 | 0.0062 | -0.0031 | 0.0093 | -0.0050 | 0.0041 | -0.0031 | 0.0039 | Threonine_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Threonine_1 (a.u) | 0.0187 | 0.0093 | 0.0238 | 0.0109 | 0.0245 | 0.0128 | 0.0300 | 0.0083 | 0.0231 | 0.0073 | 0.0180 | 0.0068 | Threonine_L0 |
| Postpradial levels at glucose oral load day: L-Threonine_1 (a.u) | -0.0031 | 0.0051 | -0.0014 | 0.0064 | -0.0024 | 0.0047 | -0.0012 | 0.0050 | -0.0005 | 0.0052 | 0.0026 | 0.0064 | Threonine_AUGlipid |
| Basal levels at lipids oral load day: L-Threonine_1 (a.u) | 0.0216 | 0.0093 | 0.0225 | 0.0083 | 0.0220 | 0.0116 | 0.0316 | 0.0061 | 0.0234 | 0.0076 | 0.0239 | 0.0111 | Threonine_P0 |
| Postpradial levels at porteins oral load day: L-Threonine_1 (a.u) | 0.0110 | 0.0075 | 0.0139 | 0.0068 | 0.0127 | 0.0092 | 0.0114 | 0.0113 | 0.0147 | 0.0058 | 0.0096 | 0.0051 | Threonine_AUGprot |
| Basal levels at glucose oral load day: Glycerol_2 (a.u) | 0.0134 | 0.0146 | 0.0233 | 0.0055 | 0.0238 | 0.0134 | 0.0313 | 0.0105 | 0.0160 | 0.0061 | 0.0180 | 0.0068 | Glycerol_G0 |
| Postpradial levels at lipids oral load day: Glycerol_2 (a.u) | -0.0042 | 0.0091 | -0.0069 | 0.0051 | -0.0074 | 0.0063 | -0.0103 | 0.0072 | -0.0019 | 0.0067 | -0.0051 | 0.0050 | Glycerol_AUGgluc |
| Basal levels at glucose proteins oral load day: Glycerol_2 (a.u) | 0.0154 | 0.0120 | 0.0280 | 0.0135 | 0.0219 | 0.0073 | 0.0291 | 0.0084 | 0.0202 | 0.0099 | 0.0181 | 0.0087 | Glycerol_L0 |
| Postpradial levels at glucose oral load day: Glycerol_2 (a.u) | -0.0003 | 0.0084 | -0.0008 | 0.0072 | -0.0013 | 0.0046 | 0.0006 | 0.0079 | -0.0035 | 0.0063 | -0.0011 | 0.0065 | Glycerol_AUGlipid |
| Basal levels at lipids oral load day: Glycerol_2 (a.u) | 0.0142 | 0.0086 | 0.0303 | 0.0115 | 0.0197 | 0.0110 | 0.0305 | 0.0155 | 0.0200 | 0.0035 | 0.0205 | 0.0096 | Glycerol_P0 |
| Postpradial levels at porteins oral load day: Glycerol_2 (a.u) | -0.0047 | 0.0071 | -0.0083 | 0.0079 | -0.0052 | 0.0082 | -0.0043 | 0.0123 | -0.0073 | 0.0035 | -0.0054 | 0.0055 | Glycerol_AUGprot |
| Basal levels at glucose oral load day: L-Serine_1 (a.u) | 0.0281 | 0.0042 | 0.0213 | 0.0032 | 0.0326 | 0.0086 | 0.0225 | 0.0060 | 0.0214 | 0.0073 | 0.0232 | 0.0066 | Serine_G0 |
| Postpradial levels at lipids oral load day: L-Serine_1 (a.u) | -0.0030 | 0.0054 | -0.0023 | 0.0041 | -0.0060 | 0.0075 | -0.0004 | 0.0038 | -0.0015 | 0.0063 | -0.0038 | 0.0051 | Serine_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Serine_1 (a.u) | 0.0269 | 0.0062 | 0.0232 | 0.0076 | 0.0256 | 0.0069 | 0.0214 | 0.0092 | 0.0221 | 0.0056 | 0.0227 | 0.0076 | Serine_L0 |
| Postpradial levels at glucose oral load day: L-Serine_1 (a.u) | 0.0009 | 0.0031 | -0.0006 | 0.0064 | -0.0008 | 0.0083 | 0.0032 | 0.0092 | -0.0009 | 0.0067 | -0.0010 | 0.0061 | Serine_AUGlipid |
| Basal levels at lipids oral load day: L-Serine_1 (a.u) | 0.0249 | 0.0083 | 0.0271 | 0.0187 | 0.0297 | 0.0096 | 0.0250 | 0.0097 | 0.0238 | 0.0074 | 0.0219 | 0.0062 | Serine_P0 |
| Postpradial levels at porteins oral load day: L-Serine_1 (a.u) | 0.0138 | 0.0087 | 0.0084 | 0.0092 | 0.0057 | 0.0091 | 0.0061 | 0.0081 | 0.0086 | 0.0043 | 0.0060 | 0.0036 | Serine_AUGprot |
| Basal levels at glucose oral load day: L-Proline_3 (a.u) | 0.0245 | 0.0066 | 0.0224 | 0.0134 | 0.0252 | 0.0053 | 0.0264 | 0.0050 | 0.0246 | 0.0071 | 0.0248 | 0.0061 | Proline_G0 |
| Postpradial levels at lipids oral load day: L-Proline_3 (a.u) | -0.0028 | 0.0038 | -0.0017 | 0.0038 | -0.0052 | 0.0035 | -0.0041 | 0.0041 | -0.0041 | 0.0047 | -0.0023 | 0.0021 | Proline_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Proline_3 (a.u) | 0.0232 | 0.0071 | 0.0217 | 0.0108 | 0.0206 | 0.0069 | 0.0299 | 0.0028 | 0.0272 | 0.0085 | 0.0201 | 0.0044 | Proline_L0 |
| Postpradial levels at glucose oral load day: L-Proline_3 (a.u) | 0.0053 | 0.0070 | 0.0051 | 0.0047 | 0.0063 | 0.0067 | 0.0038 | 0.0037 | 0.0016 | 0.0058 | 0.0031 | 0.0043 | Proline_AUGlipid |
| Basal levels at lipids oral load day: L-Proline_3 (a.u) | 0.0260 | 0.0053 | 0.0237 | 0.0082 | 0.0241 | 0.0086 | 0.0279 | 0.0036 | 0.0271 | 0.0035 | 0.0261 | 0.0077 | Proline_P0 |
| Postpradial levels at porteins oral load day: L-Proline_3 (a.u) | 0.0093 | 0.0063 | 0.0106 | 0.0035 | 0.0082 | 0.0062 | 0.0106 | 0.0062 | 0.0138 | 0.0071 | 0.0094 | 0.0078 | Proline_AUGprot |
| Basal levels at glucose oral load day: beta-Glucose_1 (a.u) | 0.1843 | 0.0431 | 0.2370 | 0.0432 | 0.2215 | 0.0490 | 0.2697 | 0.0393 | 0.2791 | 0.0386 | 0.2673 | 0.0273 | BGlucose_G0 |
| Postpradial levels at lipids oral load day: beta-Glucose_1 (a.u) | 0.0563 | 0.0646 | 0.0836 | 0.0555 | 0.0331 | 0.0710 | 0.1724 | 0.0757 | 0.1000 | 0.0777 | 0.1456 | 0.0703 | BGlucose_AUGgluc |
| Basal levels at glucose proteins oral load day: beta-Glucose_1 (a.u) | 0.1638 | 0.0412 | 0.2162 | 0.0451 | 0.2143 | 0.0553 | 0.2961 | 0.0215 | 0.2676 | 0.0170 | 0.2624 | 0.0363 | BGlucose_L0 |
| Postpradial levels at glucose oral load day: beta-Glucose_1 (a.u) | -0.0072 | 0.0140 | -0.0026 | 0.0172 | -0.0125 | 0.0208 | -0.0199 | 0.0103 | -0.0088 | 0.0117 | -0.0093 | 0.0214 | BGlucose_AUGlipid |
| Basal levels at lipids oral load day: beta-Glucose_1 (a.u) | 0.1751 | 0.0427 | 0.2334 | 0.0394 | 0.225 | 0.045 | 0.2962 | 0.0142 | 0.2541 | 0.0248 | 0.2652 | 0.0379 | BGlucose_P0 |
| Postpradial levels at porteins oral load day: beta-Glucose_1 (a.u) | -0.0126 | 0.0169 | 0.0002 | 0.0153 | -0.0234 | 0.0272 | 0.0035 | 0.0272 | 0.0133 | 0.0162 | 0.0072 | 0.0132 | BGlucose_AUGprot |
| Basal levels at glucose oral load day: D-Glucose_2 (a.u) | 0.2767 | 0.0732 | 0.3368 | 0.0713 | 0.3221 | 0.0794 | 0.4084 | 0.0404 | 0.4046 | 0.0423 | 0.3847 | 0.0544 | Dglucose_G0 |
| Postpradial levels at lipids oral load day: D-Glucose_2 (a.u) | 0.0785 | 0.0869 | 0.1128 | 0.0717 | 0.0439 | 0.0588 | 0.2101 | 0.0769 | 0.1283 | 0.0856 | 0.1876 | 0.0818 | Dglucose_AUGgluc |
| Basal levels at glucose proteins oral load day: D-Glucose_2 (a.u) | 0.2590 | 0.0797 | 0.3243 | 0.0587 | 0.3062 | 0.0690 | 0.4311 | 0.0397 | 0.4068 | 0.0320 | 0.3822 | 0.0682 | Dglucose_L0 |
| Postpradial levels at glucose oral load day: D-Glucose_2 (a.u) | -0.0157 | 0.0270 | -0.0039 | 0.0394 | -0.0152 | 0.0533 | -0.0108 | 0.0310 | -0.0140 | 0.0238 | -0.0006 | 0.0502 | Dglucose_AUGlipid |
| Basal levels at lipids oral load day: D-Glucose_2 (a.u) | 0.2523 | 0.0499 | 0.342 | 0.062 | 0.3216 | 0.0571 | 0.4141 | 0.0477 | 0.3934 | 0.0396 | 0.3918 | 0.0763 | Dglucose_P0 |
| Postpradial levels at porteins oral load day: D-Glucose_2 (a.u) | -0.0135 | 0.0196 | 0.0023 | 0.0234 | -0.0213 | 0.0384 | 0.0266 | 0.0254 | -0.0035 | 0.0306 | 0.0059 | 0.0442 | Dglucose_AUGprot |
| Basal levels at glucose oral load day: 1-Methylhistidine_1 (a.u) | 0.0050 | 0.0048 | 0.0132 | 0.0030 | 0.0102 | 0.0056 | 0.0160 | 0.0032 | 0.0145 | 0.0030 | 0.0146 | 0.0038 | Methys_G0 |
| Postpradial levels at lipids oral load day: 1-Methylhistidine_1 (a.u) | -1e-04 | 5e-04 | -0.0014 | 0.0018 | -0.0011 | 0.0013 | -0.0002 | 0.0034 | 0.0001 | 0.0013 | -0.0006 | 0.0023 | Methys_AUGgluc |
| Basal levels at glucose proteins oral load day: 1-Methylhistidine_1 (a.u) | 0.0056 | 0.0067 | 0.0139 | 0.0036 | 0.0090 | 0.0058 | 0.0165 | 0.0033 | 0.0155 | 0.0030 | 0.0154 | 0.0037 | Methys_L0 |
| Postpradial levels at glucose oral load day: 1-Methylhistidine_1 (a.u) | -0.0013 | 0.0021 | -0.0010 | 0.0025 | 0.0008 | 0.0027 | -0.0001 | 0.0017 | -0.0003 | 0.0021 | -0.0008 | 0.0015 | Methys_AUGlipid |
| Basal levels at lipids oral load day: 1-Methylhistidine_1 (a.u) | 0.0052 | 0.0050 | 0.0132 | 0.0042 | 0.0107 | 0.0068 | 0.0150 | 0.0037 | 0.0171 | 0.0038 | 0.0150 | 0.0054 | Methys_P0 |
| Postpradial levels at porteins oral load day: 1-Methylhistidine_1 (a.u) | 0.001 | 0.002 | 0.0041 | 0.0011 | 0.0007 | 0.0026 | 0.0053 | 0.0023 | 0.0036 | 0.0025 | 0.0016 | 0.0022 | Methys_AUGprot |
| Basal levels at glucose oral load day: Tyrosine_1 (a.u) | 0.0266 | 0.0063 | 0.0339 | 0.0121 | 0.0319 | 0.0086 | 0.0388 | 0.0078 | 0.0322 | 0.0082 | 0.0344 | 0.0065 | Tyrosine_G0 |
| Postpradial levels at lipids oral load day: Tyrosine_1 (a.u) | -0.0038 | 0.0038 | -0.0063 | 0.0041 | -0.0052 | 0.0062 | -0.0040 | 0.0045 | -0.0045 | 0.0056 | -0.0036 | 0.0042 | Tyrosine_AUGgluc |
| Basal levels at glucose proteins oral load day: Tyrosine_1 (a.u) | 0.0288 | 0.0106 | 0.0299 | 0.0078 | 0.0330 | 0.0088 | 0.0399 | 0.0068 | 0.0357 | 0.0089 | 0.0348 | 0.0071 | Tyrosine_L0 |
| Postpradial levels at glucose oral load day: Tyrosine_1 (a.u) | -0.0046 | 0.0052 | -0.0010 | 0.0076 | -0.0053 | 0.0043 | -0.0041 | 0.0050 | -0.0041 | 0.0065 | -0.0016 | 0.0041 | Tyrosine_AUGlipid |
| Basal levels at lipids oral load day: Tyrosine_1 (a.u) | 0.0271 | 0.0047 | 0.0336 | 0.0105 | 0.0301 | 0.0074 | 0.0419 | 0.0054 | 0.0328 | 0.0072 | 0.0379 | 0.0067 | Tyrosine_P0 |
| Postpradial levels at porteins oral load day: Tyrosine_1 (a.u) | 0.019 | 0.007 | 0.0289 | 0.0085 | 0.0149 | 0.0117 | 0.0207 | 0.0113 | 0.0269 | 0.0124 | 0.0162 | 0.0062 | Tyrosine_AUGprot |
| Basal levels at glucose oral load day: L-Phenylalanine_2 (a.u) | 0.0306 | 0.0057 | 0.0291 | 0.0053 | 0.0339 | 0.0064 | 0.0347 | 0.0043 | 0.0362 | 0.0055 | 0.0336 | 0.0051 | Phe_G0 |
| Postpradial levels at lipids oral load day: L-Phenylalanine_2 (a.u) | -0.0028 | 0.0026 | -0.0029 | 0.0028 | -0.0051 | 0.0040 | -0.0001 | 0.0038 | -0.0045 | 0.0025 | -0.0014 | 0.0029 | Phe_AUGgluc |
| Basal levels at glucose proteins oral load day: L-Phenylalanine_2 (a.u) | 0.0300 | 0.0045 | 0.0283 | 0.0058 | 0.0316 | 0.0066 | 0.0367 | 0.0030 | 0.0344 | 0.0064 | 0.0379 | 0.0065 | Phe_L0 |
| Postpradial levels at glucose oral load day: L-Phenylalanine_2 (a.u) | -0.0033 | 0.0033 | -0.0016 | 0.0032 | -0.0023 | 0.0049 | -0.0019 | 0.0033 | -0.0011 | 0.0034 | -0.0055 | 0.0053 | Phe_AUGlipid |
| Basal levels at lipids oral load day: L-Phenylalanine_2 (a.u) | 0.0310 | 0.0044 | 0.0304 | 0.0071 | 0.0309 | 0.0043 | 0.0363 | 0.0050 | 0.0347 | 0.0052 | 0.0360 | 0.0077 | Phe_P0 |
| Postpradial levels at porteins oral load day: L-Phenylalanine_2 (a.u) | 0.0083 | 0.0042 | 0.0113 | 0.0027 | 0.0090 | 0.0062 | 0.0124 | 0.0045 | 0.0120 | 0.0052 | 0.0073 | 0.0016 | Phe_AUGprot |
| Basal levels at glucose oral load day: L-Tryptophan_4 (a.u) | 0.0113 | 0.0029 | 0.0136 | 0.0032 | 0.0139 | 0.0034 | 0.0156 | 0.0035 | 0.0162 | 0.0048 | 0.0156 | 0.0026 | Tryp_G0 |
| Postpradial levels at lipids oral load day: L-Tryptophan_4 (a.u) | -5e-04 | 2e-03 | -0.0005 | 0.0018 | -0.0007 | 0.0025 | 0.0000 | 0.0032 | -0.0018 | 0.0033 | -0.0007 | 0.0027 | Tryp_AUCgluc |
| Basal levels at glucose proteins oral load day: L-Tryptophan_4 (a.u) | 0.0135 | 0.0040 | 0.0164 | 0.0025 | 0.0151 | 0.0030 | 0.0164 | 0.0023 | 0.0179 | 0.0032 | 0.0181 | 0.0034 | Tryp_L0 |
| Postpradial levels at glucose oral load day: L-Tryptophan_4 (a.u) | -0.0013 | 0.0025 | -0.0029 | 0.0007 | -0.0028 | 0.0018 | -0.0015 | 0.0018 | -0.0021 | 0.0027 | -0.0033 | 0.0028 | Tryp_AUClipid |
| Basal levels at lipids oral load day: L-Tryptophan_4 (a.u) | 0.0123 | 0.0029 | 0.0160 | 0.0037 | 0.0152 | 0.0032 | 0.0155 | 0.0028 | 0.0161 | 0.0028 | 0.0166 | 0.0048 | Tryp_P0 |
| Postpradial levels at porteins oral load day: L-Tryptophan_4 (a.u) | 0.0021 | 0.0026 | 0.0020 | 0.0024 | 0.0014 | 0.0026 | 0.0036 | 0.0038 | 0.0045 | 0.0029 | 0.0014 | 0.0037 | Tryp_AUCprot |
| Basal levels at glucose oral load day: Formate_1 (a.u) | 0.0195 | 0.0066 | 0.0124 | 0.0021 | 0.0108 | 0.0060 | 0.0162 | 0.0043 | 0.0107 | 0.0020 | 0.0129 | 0.0020 | Formate_G0 |
| Postpradial levels at lipids oral load day: Formate_1 (a.u) | -0.0016 | 0.0018 | 0.0006 | 0.0019 | 0.0000 | 0.0017 | -0.0004 | 0.0031 | 0.0002 | 0.0018 | -0.0003 | 0.0014 | Formate_AUCgluc |
| Basal levels at glucose proteins oral load day: Formate_1 (a.u) | 0.0183 | 0.0061 | 0.0130 | 0.0024 | 0.0102 | 0.0045 | 0.0161 | 0.0021 | 0.0111 | 0.0012 | 0.0131 | 0.0013 | Formate_L0 |
| Postpradial levels at glucose oral load day: Formate_1 (a.u) | 0.0000 | 0.0033 | 0.0001 | 0.0021 | -0.0001 | 0.0015 | -6e-04 | 2e-03 | -0.0010 | 0.0015 | -0.0001 | 0.0014 | Formate_AUClipid |
| Basal levels at lipids oral load day: Formate_1 (a.u) | 0.0195 | 0.0071 | 0.0118 | 0.0025 | 0.0102 | 0.0051 | 0.0168 | 0.0057 | 0.0097 | 0.0018 | 0.0135 | 0.0022 | Formate_P0 |
| Postpradial levels at porteins oral load day: Formate_1 (a.u) | 0.0023 | 0.0019 | 0.0016 | 0.0015 | 0.0011 | 0.0015 | -0.0018 | 0.0050 | 0.0007 | 0.0022 | -0.0001 | 0.0013 | Formate_AUCprot |
> (p <- ncol(metabolome))[1] 263> (n <- nrow(metabolome))[1] 53> (num_metabolites <- length(colnames(metabolome)[grep("mean", colnames(metabolome))]))[1] 37We observe from the data that we have 263 variables. From this variables, 259 are the variables belonging to the metabolites. The 4 that we have subtracted correspond to the order, sample name, group, and obese group. From the 259 variables that corresponds to the metabolites, only 37 are actual metabolites. For each metabolite, they calculated the mean basal value, the three days at basal time, and three days at postprandial time.
Before we explore the distribution of the metabolites, at basal time and at postprandial stage, let’s observe the correlation of the mean basal values for all metabolites,
> corrplot(cor(metabolome[, grep("mean", colnames(metabolome))]), lab_size = 1)
We can observe several patterns of positive correlation, and a few negative correlations. This is maybe due to the physical properties of the metabolites. For example, one can see that Oxoisocaproic, Leucine, Isoleucine and Valine are positive correlated. These metabolites have in common that the Oxoisocaproic acid, is derived from the leucine, isoleucine, and valine. And leucine, isoleucine and valine are non-polar.
> variables <- colnames(metabolome)
> hist.list.meta <- list() ## initizalize a list of the histogram
> ## plot all histograms via loop
> for (i in 1:length(variables)) {
+ if (variables[i] == "Order" || variables[i] == "Sample") {
+ next
+ } else if (class(metabolome[, i]) == "factor") {
+ next
+ }
+ variable <- variables[i] ## name of the variable to plot
+ titulo <- colnames(metabolome)[i] # title of the varialbe
+
+ breaks <- pretty(range(metabolome[, variable]), n = nclass.Sturges(metabolome[,
+ variable]), min.n = 1) # make pretty histogram by appropiate bins
+ bwidth <- breaks[2] - breaks[1] ## bin width
+
+ ## plot
+ hist.list.meta[[i]] <- ggplot(metabolome, aes_string(x = variable)) + geom_histogram(aes(y = ..density..),
+ binwidth = bwidth, colour = "black") + geom_density(alpha = 0.2, fill = "lightblue") +
+ xlab(titulo) + ylab("")
+
+
+ }
>
>
> bp.interaction <- list() ## intialize boxplot list interaction
> for (i in 1:length(variables)) {
+ titulo <- colnames(metabolome)[i]
+ variable <- variables[i]
+ bp.interaction[[i]] <- ggplot(metabolome, aes_string(x = GROUP, y = variable,
+ interaction(GROUP), fill = OBESE)) + geom_boxplot() + ylab(titulo) + xlab("")
+
+ }Distributions of the basal concentrations of the metabolites.
> do.call(grid.arrange, hist.list.meta[3:11])
> do.call(grid.arrange, hist.list.meta[12:20])
> do.call(grid.arrange, hist.list.meta[21:29])
> do.call(grid.arrange, hist.list.meta[30:38])
> hist.list.meta[39][[1]]
From the distributions of the metabolites, one can observe, that leucine, isuleucine, alanine, glycloprotein, acetone, glutamic acid, glutamin, citrate, aspargine, ornithine, carnitine, betaine, glycine, threonine, glycerol, serine, tyrosine, phenylalanine,and tryptophan, more or less follow a normal distribution, the other metabolites, oxoisocaproic, valine, isobutyric, oxoisovaleric, hydroxibutyric, lactate, acatetate pyruvate, pyroglutamic, creatinine, creatine, lysine, proline, beta glucose, d glucose, methylhistidine, and formate, tend to follow skewed distributions.
> auxtst <- function(datos, columna) {
+
+ y <- as.data.frame(datos[, columna])
+ colnames(y) <- colnames(datos)[columna]
+ # print(unlist(y))
+ obeso <- datos[, "OBESE"]
+ grupo <- datos[, "GROUP"]
+ print(paste("anova de..", names(y)))
+ print(colnames(datos)[columna])
+ s <- summary(aov(unlist(y) ~ obeso + grupo + obeso:grupo))
+ s <- s[[1]]
+
+ if (any(complete.cases(s$`Pr(>F)` < 0.05))) {
+ print(paste("Existen diferencias entre grupos con la variable", names(y)))
+ s.g <- pairwise.t.test(unlist(y), grupo)$p.value < 0.05
+ s.o <- pairwise.t.test(unlist(y), obeso)$p.value < 0.05
+ z.inter <- pairwise.t.test(unlist(y), obeso:grupo)$p.value < 0.05
+ print("entre grupo")
+ print(s.g)
+ print("entre obeso")
+ print(s.o)
+ print("interaccion")
+ print(z.inter)
+
+ }
+ }2-Oxoisocaproic acid_2
> meta <- grep("oxoisoca", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Oxicocaproic ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Oxicocaproic") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
For the mean basal concentration values of Oxoisocoaproic, we can observe that there are differences between control women, PCOS patients and males, being the concentration levels of this metabolites higher in men, followed by PCOS women and in healthy women. Furthermore there are differences between obese subjects, but not between men. It seems that there is no differences between non-obese PCOS women and obese women. There is not differences between men and obese PCOS obese patients. If we take a closer observation in basal days, there is not differences between days, having the main relationships as in the mean of the three days.
At postprandial time, the concentration of this metabolite is lower in comparison with basal time. We cannot observe differences between groups at the first day, neither on the second but on the last day, on non-obese males, the concentration is higher than non-obese females. Non-obese men, have similar concentration values than all obsese subjects,
Leucine_1
> meta <- grep("Leu_", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Leucine_1 ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Leucime_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p2)
The mean basal levels of Lucine_1 seems not to have differences between obese and non-obese subjects. Though there is a slight difference between obese PCOS women and non-obese PCOS women, being higher the levels of this metabolite in PCOS obese women. Between sex, the concentration levels are higher in males than females. Takin a close look at each basal day, the values are higher on the glucose oral load day. Being higher on males and obese subjetcts than females, but similar values between obese PCOS women and males. For the rest of the days, there it seems no differences relay between groups.
Postprandial levels are lower than basal levels. Across all days, non-obese males, present higher levels of this metabolite than obese men. Similar pattern but with lower levels, are present in PCOS women, being higher in obese ones. Similar pattern between control women are present.
Isoleucine_1
> meta <- grep("Isoleu", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Isoleucine_1 ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Isoleucine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of Isoleucine_1 are higher in obese PCOS females than non-obese females with similar values on men. Looking at each day, similar pattern is observed.
Basal levels are higher than at postprandial stage. At each day of the study, no difference is observed among groups, except last day, on the protein load day. Where these values are higher than the rest of the previous days. The highest values are for non-obese males, but there is not differences between groups and obese subjects, except on males.
L-valine
> meta <- grep("valine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Valine ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Valine") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
The mean basal levels of this metabolites, are higher on obese females, with similar values in comparison with men. PCOS women have higher values than control women. Similar pattern it is observed on each day.
Postprandial levels are lower than basal levels. The third day, subjects present higher concentration, with no distinction between groups.
Isobutyric acid_1
> meta <- grep("Isobutyric", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Isobutyric acid ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Isobutyric acid ") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Isbutyric acid levels, at basal time on non-obese females, are higher than obese females. There is no distinction between men. On each day, similar pattern is observed.
Basal values are higher than postprandial levels. Not distinction between groups is observed at each day. On the last day, higher values are present across all subjects.
2-oxoisovaleric acid_1
> meta <- grep("Oxoisovaleric", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Oxoisovaleric ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Oxoisovaleric") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of Oxoisovaleric acid are higher in obese women than non-obese women. With similar values in comparison with men. Higher values of PCOS women are present. Each day show similar patterns. Obese PCOS women show highest values across all days.
Postprandial levels are lower than basal levels. No differences between groups are present across all days.
3-Hydroxybutyric acid_1
> meta <- grep("ohbutyric", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal 3-Hydroxybutyric acid_1 ") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial 3-Hydroxybutyric acid_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal mean values shows no differences between groups. Obese PCOS women show barely higher levels than non-obese PCOS females. At the second day, if we observe basal levels, men have the higher concentration.
Here, there is almost indistinguishable differences between basal and postprandial levels of this metabolite. However, on the second day, values increases across all subjects, with similar values in comparison with basal levels. Women show higher values of this metabolites than men on this day.
Lactate_1
> meta <- grep("lactate", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Lactate ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Lactate ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Lactate mean basal values are higher in obese PCOS women than non-obese, but not more differences are observed across all subjects. Basal values are higher than postprandial values. Being higher on the first day. No differences between groups are observed.
Alanine
> meta <- grep("alanine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Alanine_1 ") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Alanine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of alanine are higher in obese subjects than non-obese, but this relationship is only observable in men and women with PCOS. Separately on each day, one can visualize than regarfing obesity, women with PCOS have higher concentrations of this metabolite.
Basal levels are higher than a postprandial stage. The lipid load day, thhe subjects present lower concentration of Alanine. across all days no differences are observed between subjects. Higher values are present on the first day in comparison with the second. On the last day, the protien load day, subjects present higher levels of Alanine than the other days.
Acetate
> meta <- grep("acetate", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Acetate_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Acetate_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of acetate are higher in non-obese females in comparison with obese females. The contrary happens with men. Healthy women present higher values than PCOS non-obese patients. But obese PCOS women have higher values than control obese women. Similar values between men and PCOS women are present. Obese men have higher values than obese females, and obese PCOS women have higher values than obese control females.
Basal values are higher in comparison with postprandial levels. There are not observable differences across subjects among all postprandial days.
N-Ac-Glycoprotein_signals_1
> meta <- grep("glycoprot", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal N-Ac-Glycoprotein_signals_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial N-Ac-Glycoprotein_signals_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of N-Ac-Glycoprotein_signals_1 are higher on obese PCOS women than the rest of the subjects. However, non-obese control subjects have higher values than obese control subjects.
Basal levels are higher in comparison with postprandial levels. No differences between groups across all days are observed.
Acetone_1
> meta <- grep("acetone", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Acetone_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Acetone_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of acetone, are higher on obese subjects. Obese PCOS women have higher values than men. PCOS women and men have higher values than females. Regarding non-obese subjects, men have the highest values. But on obese subjects, PCOS women have the highest values, enven higher than control healthy men.
Basal levels are higher in comparison with postprandial levels. The second and the third day, men have the highest values. IN obese subjects, no difference it is present. But on the second and third days, levels are higher.
L-Glutamic acid_1
> meta <- grep("gluacid", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Glutamic acid_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Glutamic acid_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of L-Glutamic acid_1 are higher in obese PCOS women and obese men. With no differences between control females.
Higher values of this metabolite are present at basal time in comparison with postprandial times. The last day, the values are almost comparable with postprandial levels, on the protein load day. Control non-obese subjects present higher concentration of this metabolite than PCOS women. Howhever, no differences are observed on this day between obese subjects.
Pyruvate_1
> meta <- grep("pyruvate", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Pyruvate_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Pyruvate_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of pyruvate, are higher in obese subjects. This difference is observed only on females. But higher values are present on obese PCOS women. PCOS women and men have higher values than control women.
At postprandial levels, these are lower than basal levels. However ob obese subjects, similar values are observed at both stages. Specially on the first and last days. Postprandial levels of non obese men are higher. However on the first day, on obese PCOS women, these levels arises its maximum.
Pyroglutamic acid
> meta <- grep("pyroglu", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Pyroglutamic acid") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Pyroglutamic acid") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of Pyroglutamic acid are higher in non-obese subjects, being this difference not observable in PCOS women.
Postprandial leves are lower than basal levels. At the second day, the lipid oral day, these values increases being comparable wih basal levels. Being higher this values in women with CPOS.
L-Glutamine_1
> meta <- grep("gln", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Glutamine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Glutamine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal values of glutamine are higher in obese subjects, but this difference is only observable in women. With highest values in obese women with PCOS.
Postprandial levels are lower than basal levels. Each day after the macronutrients loads increase than the day before, with no differences between groups. Only on obese subjects, at the second day, obese females have higher conenctration than non-obese men.
Citrate
> meta <- grep("citrate", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Citrate_2") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Citrate_2") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of citrate are higher in non-obese subjects. However, this difference is not observable in females with PCOS. However PCOS obese women have the highest values of this metabolite.
Lower levels at postprandial levels in comparison with basal levels is observed. Being this values higher on the first 2 days. Obese PCOS women, present on this days, higher concentration of this metabolite.
L-Asparagine_4
> meta <- grep("asn", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Asparagine_4") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Asparagine_4") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Mean basal levels of aspargine are similar between groups and across all days. Lower levels at postprandial time are observed in comparison with basal levels. However on the last day, similar values in comparison with basal values is observed. With no distiction between groups.
Creatinine_1
> meta <- grep("creatinine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Creatinine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Creatinine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of Creatinine_1 are higher in obese PCOS women. With no diffence on the other groups. Postprandial levels are lower than basal levels, with no distinction between groups across all days.
Creatine_1
> meta <- grep("creatine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Creatine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Creatine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Creatine basal levels are higher in obese PCOS women in comparison with the rest of the subjects. Lower levels in men than women are observed. No difference between control women is observed. Obese men have higher levels than non-obese men.
Postrprandial levels are lower than basal levels. On the first day PCOS women show higher values. But the last day, all subjects present similar values in comparison with the basal measures.
Lysine_1
> meta <- grep("lysine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Lysine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Lysine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of lysisne are higher in obese subjects, but this difference is observable only between women. PCOS women have higher values than control women. And PCOS obese women have similar values than men.
Postprandial levels are lower than basal levels. Except on the protein load day. Withsimilar values. Non-obese men, and non-obese PCOS women have higher values than control women. And obese PCOS women present higher values than the other obese subjects.
Ornithine_1
> meta <- grep("Ornithine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Ornithine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Ornithine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of Ornithine are higher in obese subjects, but this difference is observable only between women. PCOS women have higher values than control women. And PCOS obese women have similar values than men.
Postprandial levels are lower than basal levels. Remain similar across all days. No differences between groups are present.
Choline_1
> meta <- grep("choline", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Choline_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Choline_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
No differences at present at basal levels. Neither at postprandial levels. Postprandial levels are lower than basal levels.
L-Carnitine_1
> meta <- grep("carnitine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Carnitine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Carnitine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
The mean basal values of L-carnitine_1 are higher in control women with similar values in men. Non-obese women, present higher values than obese women in general. Non-obese males, present higher values than obese men, and PCOS obese women, present higher values than non-obese PCOS women.
Higher levels on basal stage are present in comparison with postprandial time. With no observable differences among groups
Betaine_1
> meta <- grep("betaine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Betaine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Betaine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Betaine basal levels are higher in non-obese subjects in general. Apart form this observation no differences are present.
Basal values are higher than postprandial values. No differences are observed at this stage in general. However on the last day, non-obese controls have higher values than PCOS non-obese women.
Glycine_1
> meta <- grep("glycine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Glycine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Glycine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal values of glycine are higher in PCOS women and in men if we compare with control women. No differences are observed between obese and non-obese subjects.
Similar relationship is present in postprandial time. Furthermore, basal values are higher than postprnandial levels.
L-Threonine_1
> meta <- grep("threonine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Threonine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Threonine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of threonine, are higher in women with PCOS and men, being similar these values in comparison with control women. No difference between obese and obese subjects is observed.
Basal levels are higher than postpranidal levels. With no differences between groups. However, on the last day, these values are similar in comparison with basal levels.
Glycerol_2
> meta <- grep("glycerol", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Glycerol_2") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Glycerol_2") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Glycerol basal levels are higher on obese subjects in comparison with non-obese subjects. PCOS women have higher values in comparison with control women. With similar values compared with men. Looking closely, obese men have lower values than females.
In general lower levels at postprandial stage are present in comparison with basal levels. There are not differences between groups.
L-Serine_1
> meta <- grep("serine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Serine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Serine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of serine are higher in non-obese subjects. PCOS non-obese women show higher concentrations of these metabolite than the other non-obese subjects. Between obese subjects, there are no differences between groups.
Postprandial levels are lower than basal levels. Except on the last day. On that day, similar values are present. PCOS women except on the last day, show higher levels of serine.
L-Proline_3
> meta <- grep("proline", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Proline_3") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Proline_3") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of proline are higher in non-obese control subjects in comparison with non-obese. However, obese PCOS women show higher values than non-obese PCOS women. PCOS women show higher values than the rest of the subjects.
Postprandial levels are lower than basal levels. Each day values of this metabolite increases. With no differences between groups and obese subjects. The last day, comparable measures are observed between postprandial and basal levels.
beta-Glucose_1
> meta <- grep("bglucose", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal beta-glucose_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial beta-glucose_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of beta_glucose, are higher in PCOS women and men in comparison with control women. Non-obese PCOS women show similar values than obese control women. Obese PCOS women, and have the highest values. And PCOS women have similar values in comparison with men.
Postprandial levels are lower than basal levels. However on the first day, these values are comparable with basal levels. Being higher on obese subjects. And obese PCOS women show the highest values at postprandial levels. PCOS non-obese women present similar values, but lower than normal men.
D-Glucose_2
> meta <- grep("dglucose", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal D-Glucose_2") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial D-Glucose_2") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of D_glucose, are higher in PCOS women and men in comparison with control women. Non-obese PCOS women show similar values than obese control women. Obese PCOS women, and have the highest values. And PCOS women have similar values in comparison with men.
Postprandial levels are lower than basal levels. However on the first day, these values are comparable with basal levels. Being higher on obese subjects. And obese PCOS women show the highest values at postprandial levels. PCOS non-obese women present similar values, but lower than normal men.
1-Methylhistidine_1
> meta <- grep("methys", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal 1-Methylhistidine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial 1-Methylhistidine_1") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of 1-Methylhistidine_1 are higher in obese women in comparison with non-obese women. PCOS women have higher values than control women. Obese PCOS women have similar values than men. No difference between obese and non-obese men are present.
Postprandial levels are lower than basal levels. However on the last day, higher levels are present, even comparable with basal levels. Non-obese PCOS women and men on the second day have similar values, and higher than non-obese women. On the last day, non-obese males show higher values, similar with basal values of healthy control women. Similar values are present on obese females. Non obese females both PCOS and control show similar values. The rest of the days no differences are present.
Tyrosine_1
> meta <- grep("tyrosine", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Tyrosine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Tyrosine_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of tyrosine are higher on obese subjects, being higher in men and PCOS women than control women.
Postprandial levels are lower in comparison with basal levels. However, the last day, though there are not differences between groups, these values are comparable with basal levels.
L-Phenylalanine_2
> meta <- grep("phe", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Phenylalanine_2") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Phenylalanine_2") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of phenilalanine are similar across subjects. However a slightly difference is observed in PCOS women and men, being this values similar but higher than control women.
Postprandial levels are lower than basal levels, except on the last day. Higher than the rest of the days, but still lower than basal levels. On obese subjects, males have the lower value. PCOS women have the higher value on the last day. The rest of the day no differences are present, except on the second day on obese males with the lowest values.
L-Tryptophan_4
> meta <- grep("tryp", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal L-Tryptophan_4") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial L-Tryptophan_4") +
+ theme(axis.text.x = element_text(angle = 45, vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of tryptophan are higher in obese females than non-obese females. Between men there is not observable difference. Though levels in men are higher than females.
Postprandial levels are lower than basal levels. Except on the last day, being higher for non-obese males, and comparable with obese PCOS women. Still lower values than basal levels.
Formate_1
> meta <- grep("formate", ignore.case = T, colnames(metabolome))
> meta.mean <- meta[1]
> meta.plts <- meta[-1]
> ### plots
> i1 <- bp.interaction[meta.mean][[1]]
> p1 <- bp.1.vars(metabolome, meta.plts[c(1, 3, 5)], "Basal Formate_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
> p2 <- bp.1.vars(metabolome, meta.plts[c(2, 4, 6)], "Postprandial Formate_1") + theme(axis.text.x = element_text(angle = 45,
+ vjust = 0.9, hjust = 1, size = 7))
>
> grid.arrange(i1, p1, p2)
Basal levels of formate, have the highest value on healthy control women. However, obese PCOS and obese males have higher values than non-obese subjects. Control women have higher values than PCOS women. PCOS obese women have highly values than men.
Postprandial levels are comparable with basal levels. Being lower on the first and second day. Obese control women show higher values at postprandial stage.
Multivariate descriptiva analysis
> X <- metabolome[, -c(1, 2, 262, 263)]Statistical multivariate descriptive analysis.
First of all let’s create a dataframe with the data.
> plotPCA_methods <- function(X.list, factor, title1, title2, size = 1.5, glineas = 0.25,
+ labels.scores, labels.loads) {
+
+ X.scores <- X.list$scores
+ X.loadings <- X.list$loadings
+ colnames(X.scores) <- paste0("PC", 1:dim(X.scores)[2])
+
+ colnames(X.loadings) <- paste0("PC", 1:dim(X.loadings)[2])
+ varianza <- as.data.frame(X.list$var)
+ varianza$PC <- paste0("PC", 1:dim(X.loadings)[2])
+ colnames(varianza) <- c("varianza", "PC")
+ # scores
+ X.scores <- as.data.frame(X.scores)
+ Group <- factor[[1]]
+ Group2 <- factor[[2]]
+ colores <- 1:length(levels(Group))
+ # main plot
+ p1 <- ggplot(X.scores, aes(x = PC1, y = PC2)) + theme_classic() + geom_hline(yintercept = 0,
+ color = "gray70") + geom_vline(xintercept = 0, color = "gray70") + geom_point(aes(color = Group,
+ shape = Group2), alpha = 0.55, size = 3) + coord_cartesian(xlim = c(min(X.scores[,
+ 1]), max(X.scores[, 1]))) + scale_fill_discrete(name = "Group")
+ # avoiding labels superposition
+
+ grafico <- p1 + geom_text_repel(aes(y = PC2, label = labels.scores), segment.size = 0.25,
+ size = size) + labs(x = c(paste("PC1", round(varianza[1, 1], 2), "%")), y = c(paste("PC2",
+ round(varianza[2, 1], 2), "%"))) + ggtitle(paste("Principal Component Analysis for: ",
+ title1, sep = " ")) + theme(plot.title = element_text(hjust = 0.5)) + scale_color_manual(values = colores)
+
+ X.loadings <- as.data.frame(X.loadings)
+ # main plot
+ p2 <- ggplot(X.loadings, aes(x = PC1, y = PC2)) + theme_classic() + geom_hline(yintercept = 0,
+ color = "gray70") + geom_vline(xintercept = 0, color = "gray70") + geom_point(aes(color = "gray70"),
+ alpha = 0.55, size = 3) + coord_cartesian(xlim = c(min(X.loadings[, 1]),
+ max(X.loadings[, 1])))
+ # avoiding labels superposition
+
+ grafico2 <- p2 + geom_text_repel(aes(label = labels.loads), segment.size = 0.25,
+ size = size) + labs(x = c(paste("PC1", round(varianza[1, 1], 2), "%")), y = c(paste("PC2",
+ round(varianza[2, 1], 2), "%"))) + ggtitle(paste("Principal Component Analysis for: ",
+ title2, sep = " ")) + theme(plot.title = element_text(hjust = 0.5)) + theme(legend.position = "none")
+
+ graficos <- list(grafico, grafico2)
+ return(graficos)
+ }> grupos <- list(general_data$GROUP, general_data$OBESE)Because we are leading with more variables than observations, we are going to perform three approaches. 1. Simply by computing a PCA on the traspose data (prcomp and princomp) 2. Nipals algorithm 3. Sparse PCA
prcomp and princomp
> pcxt <- prcomp(t(X), center = T, scale = F)
> list.pcxt <- list(scores = pcxt$rot, loadings = pcxt$x, var = 100 * pcxt$sdev^2/sum(pcxt$sdev^2))> graficos <- plotPCA_methods(list.pcxt, factor = grupos, title1 = "scores ", title2 = "loadings",
+ labels.scores = rownames(X), labels.loads = colnames(X))
> graficos[[1]]
[[2]]
> # graficos[[2]]NIPALS
> n <- nrow(X)
> pcx.nipals <- chemometrics::nipals(X, a = ncol(X), it = 200)actual precision: 3.560737
actual precision: 2.363613
actual precision: 0.6319139
actual precision: 0.1688412
actual precision: 0.0482151
actual precision: 0.01430987
actual precision: 0.004360598
actual precision: 0.001352242
actual precision: 0.0004239665
actual precision: 0.0001338072
actual precision: 4.239442e-05
actual precision: 2.318207
actual precision: 0.767327
actual precision: 0.5187698
actual precision: 0.4105877
actual precision: 0.3440151
actual precision: 0.2830158
actual precision: 0.2258181
actual precision: 0.1759603
actual precision: 0.135022
actual precision: 0.102653
actual precision: 0.07762294
actual precision: 0.05851394
actual precision: 0.04403121
actual precision: 0.03309989
actual precision: 0.02486832
actual precision: 0.01867787
actual precision: 0.01402587
actual precision: 0.01053145
actual precision: 0.007907178
actual precision: 0.005936642
actual precision: 0.004457099
actual precision: 0.003346257
actual precision: 0.002512255
actual precision: 0.001886109
actual precision: 0.001416019
actual precision: 0.001063092
actual precision: 0.0007981276
actual precision: 0.0005992026
actual precision: 0.0004498575
actual precision: 0.0003377352
actual precision: 0.0002535581
actual precision: 0.0001903613
actual precision: 0.0001429157
actual precision: 0.0001072954
actual precision: 8.055312e-05
actual precision: 2.173066
actual precision: 0.659481
actual precision: 0.3624173
actual precision: 0.1866028
actual precision: 0.09406453
actual precision: 0.04714015
actual precision: 0.02358761
actual precision: 0.01179786
actual precision: 0.005900363
actual precision: 0.002950822
actual precision: 0.001475722
actual precision: 0.0007380153
actual precision: 0.0003690847
actual precision: 0.0001845809
actual precision: 9.23097e-05
actual precision: 1.677439
actual precision: 0.2567311
actual precision: 0.1071902
actual precision: 0.04568754
actual precision: 0.0200117
actual precision: 0.009082403
actual precision: 0.004296075
actual precision: 0.002118293
actual precision: 0.001082462
actual precision: 0.0005681341
actual precision: 0.0003035983
actual precision: 0.0001640693
actual precision: 8.926138e-05
actual precision: 1.106112
actual precision: 0.1739612
actual precision: 0.1595374
actual precision: 0.1747013
actual precision: 0.1857912
actual precision: 0.1835904
actual precision: 0.1675496
actual precision: 0.1428299
actual precision: 0.1157825
actual precision: 0.09077646
actual precision: 0.06971829
actual precision: 0.05289584
actual precision: 0.03985121
actual precision: 0.02990378
actual precision: 0.02238891
actual precision: 0.0167414
actual precision: 0.01250962
actual precision: 0.009343839
actual precision: 0.00697768
actual precision: 0.005210069
actual precision: 0.00388997
actual precision: 0.002904239
actual precision: 0.00216825
actual precision: 0.001618755
actual precision: 0.00120851
actual precision: 0.0009022304
actual precision: 0.0006735719
actual precision: 0.0005028633
actual precision: 0.0003754184
actual precision: 0.0002802729
actual precision: 0.0002092409
actual precision: 0.0001562111
actual precision: 0.0001166212
actual precision: 8.706482e-05
actual precision: 1.089033
actual precision: 0.1252613
actual precision: 0.05921336
actual precision: 0.03284539
actual precision: 0.01839416
actual precision: 0.01034205
actual precision: 0.005829689
actual precision: 0.003291685
actual precision: 0.001860707
actual precision: 0.001052602
actual precision: 0.0005957614
actual precision: 0.0003373138
actual precision: 0.0001910309
actual precision: 0.0001082055
actual precision: 6.129854e-05
actual precision: 0.6884149
actual precision: 0.250503
actual precision: 0.06300694
actual precision: 0.03976089
actual precision: 0.03012283
actual precision: 0.02371211
actual precision: 0.01904033
actual precision: 0.01551241
actual precision: 0.01278577
actual precision: 0.01063976
actual precision: 0.008924323
actual precision: 0.007534164
actual precision: 0.006393927
actual precision: 0.005448863
actual precision: 0.004658627
actual precision: 0.003993039
actual precision: 0.003429152
actual precision: 0.002949213
actual precision: 0.002539254
actual precision: 0.0021881
actual precision: 0.001886681
actual precision: 0.001627541
actual precision: 0.001404481
actual precision: 0.001212304
actual precision: 0.001046624
actual precision: 0.0009037151
actual precision: 0.0007804018
actual precision: 0.0006739677
actual precision: 0.0005820833
actual precision: 0.0005027475
actual precision: 0.0004342387
actual precision: 0.0003750744
actual precision: 0.0003239768
actual precision: 0.000279844
actual precision: 0.0002417255
actual precision: 0.0002088006
actual precision: 0.0001803614
actual precision: 0.0001557963
actual precision: 0.0001345773
actual precision: 0.0001162485
actual precision: 0.0001004162
actual precision: 8.674021e-05
actual precision: 0.4177731
actual precision: 0.4328088
actual precision: 0.1373386
actual precision: 0.07595771
actual precision: 0.06100971
actual precision: 0.05252296
actual precision: 0.04597372
actual precision: 0.0404176
actual precision: 0.03551747
actual precision: 0.03113506
actual precision: 0.02720997
actual precision: 0.02370879
actual precision: 0.02060405
actual precision: 0.01786706
actual precision: 0.01546676
actual precision: 0.01337074
actual precision: 0.01154669
actual precision: 0.009963527
actual precision: 0.008592248
actual precision: 0.007406337
actual precision: 0.006381938
actual precision: 0.00549783
actual precision: 0.004735303
actual precision: 0.004077961
actual precision: 0.003511501
actual precision: 0.003023492
actual precision: 0.002603153
actual precision: 0.002241155
actual precision: 0.001929435
actual precision: 0.001661033
actual precision: 0.001429943
actual precision: 0.001230988
actual precision: 0.001059704
actual precision: 0.0009122463
actual precision: 0.0007853033
actual precision: 0.0006760223
actual precision: 0.000581947
actual precision: 0.0005009621
actual precision: 0.0004312465
actual precision: 0.0003712323
actual precision: 0.0003195697
actual precision: 0.0002750966
actual precision: 0.0002368125
actual precision: 0.0002038561
actual precision: 0.0001754862
actual precision: 0.0001510643
actual precision: 0.0001300412
actual precision: 0.0001119437
actual precision: 9.636483e-05
actual precision: 0.3652057
actual precision: 0.424951
actual precision: 0.1618432
actual precision: 0.06812883
actual precision: 0.04374072
actual precision: 0.03175099
actual precision: 0.02359467
actual precision: 0.0176065
actual precision: 0.01314283
actual precision: 0.009807724
actual precision: 0.007316548
actual precision: 0.005456892
actual precision: 0.00406933
actual precision: 0.00303434
actual precision: 0.002262479
actual precision: 0.001686914
actual precision: 0.001257751
actual precision: 0.0009377618
actual precision: 0.0006991789
actual precision: 0.0005212942
actual precision: 0.0003886663
actual precision: 0.0002897813
actual precision: 0.0002160547
actual precision: 0.0001610857
actual precision: 0.000120102
actual precision: 8.954541e-05
actual precision: 0.3003948
actual precision: 0.30248
actual precision: 0.2398763
actual precision: 0.103433
actual precision: 0.04696875
actual precision: 0.02494462
actual precision: 0.01468598
actual precision: 0.009229033
actual precision: 0.006086672
actual precision: 0.004168186
actual precision: 0.002934895
actual precision: 0.002106201
actual precision: 0.001530046
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WARNING! Iteration stop in h= 19 without convergence!
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actual precision: 6.402723e-63
actual precision: 3.328857e-63
actual precision: 4.360695e-63
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actual precision: 3.457131e-63
actual precision: 3.576776e-63
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actual precision: 3.022328e-63
actual precision: 2.591327e-63
actual precision: 1.214216e-63
actual precision: 1.787771e-63
actual precision: 1.21045e-63
actual precision: 9.941372e-64
actual precision: 1.012105e-63
actual precision: 1.017569e-63
actual precision: 1.015312e-63
actual precision: 1.130182e-63
actual precision: 1.072322e-63
actual precision: 8.386293e-64
actual precision: 6.707645e-64
actual precision: 5.990048e-64
actual precision: 6.151248e-64
actual precision: 6.219152e-64
actual precision: 6.13892e-64
actual precision: 7.104215e-64
actual precision: 5.652057e-64
actual precision: 6.549128e-64
actual precision: 5.80303e-64
actual precision: 6.04566e-64
actual precision: 5.328562e-64
actual precision: 6.225633e-64
actual precision: 5.497125e-64
actual precision: 5.021463e-64
actual precision: 4.389967e-64
actual precision: 5.665387e-64
actual precision: 4.070486e-64
actual precision: 4.592961e-64
actual precision: 4.700772e-64
actual precision: 4.678992e-64
actual precision: 4.33522e-64
actual precision: 4.515042e-64
actual precision: 3.874647e-64
actual precision: 4.401387e-64
actual precision: 3.35075e-64
actual precision: 3.688842e-64
actual precision: 3.678611e-64
actual precision: 4.407389e-64 > pcx.nipals_variance <- 100 * diag(t(pcx.nipals$T) %*% pcx.nipals$T)/sum(diag(t(pcx.nipals$T) %*%
+ pcx.nipals$T))
> list.nipals_1 <- list(scores = pcx.nipals$T, loadings = pcx.nipals$P, varianza = pcx.nipals_variance)> graficos <- plotPCA_methods(list.nipals_1, factor = grupos, title1 = "scores ", title2 = "loadings",
+ labels.scores = rownames(X), labels.loads = colnames(X))
> graficos[[1]]
> graficos[[2]]
Sparse PCA
Let’s create a function to fix beta andcontrol sparsity.
> perf <- function(X, X.pred) {
+
+ return(abs(norm(X - X.pred, type = "F"))/norm(X, type = "F"))
+
+ }
>
> spca.perf <- function(X, fix_parameter, transpose) {
+
+ parameter <- seq(1e-10, 1, 0.01)
+ perf.vector <- vector(mode = "numeric", length = length(parameter))
+ if (fix_parameter == "alpha") {
+
+ beta <- parameter
+ alpha <- 1e-04
+ if (transpose == F) {
+
+ for (i in 1:length(parameter)) {
+ perf.vector[i] <- perf(as.matrix((X)), t(spca((X), alpha = alpha,
+ beta = beta[i], center = T, scale = T, verbose = F, k = ncol(X))$loadings))
+
+ }
+ beta <- beta[which.min(perf.vector)]
+ pcx <- spca(X, alpha = alpha, beta = beta, verbose = F, center = T, scale = T,
+ k = ncol(X))
+
+ } else if (transpose == T) {
+
+ for (i in 1:length(parameter)) {
+ perf.vector[i] <- perf(as.matrix(t(X)), (spca(t(X), alpha = alpha,
+ beta = beta[i], verbose = F, center = T, scale = T, k = ncol(X))$scores))
+
+ }
+ beta <- beta[which.min(perf.vector)]
+ pcx <- spca(t(X), alpha = alpha, beta = beta, verbose = F, center = T,
+ scale = T, k = ncol(X))
+ }
+
+ } else if (fix_parameter == "beta") {
+
+ alpha <- parameter
+ beta <- 1e-04
+ if (transpose == F) {
+
+ for (i in 1:length(parameter)) {
+ perf.vector[i] <- perf(as.matrix((X)), t(spca((X), alpha = alpha[i],
+ beta = beta, center = T, scale = T, verbose = F, k = ncol(X))$loadings))
+
+ }
+ alpha <- alpha[which.min(perf.vector)]
+ pcx <- spca(X, alpha = alpha, beta = beta, verbose = F, center = T, scale = T,
+ k = ncol(X))
+ } else if (transpose == T) {
+
+ for (i in 1:length(parameter)) {
+ perf.vector[i] <- perf(as.matrix(t(X)), (spca(t(X), alpha = alpha[i],
+ center = T, scale = T, beta = beta, verbose = F, k = ncol(X))$scores))
+
+ }
+
+ alpha <- alpha[which.min(perf.vector)]
+ pcx <- spca(t(X), alpha = alpha, beta = beta, center = T, scale = T,
+ verbose = F, k = ncol(X))
+ }
+
+
+ }
+
+ return(pcx)
+ }> # pcx.a <- spca.perf(X,'beta',transpose = F) pcx.a.t <-
> # spca.perf(X,'beta',transpose=T)
> pcx.b <- spca.perf(X, "alpha", transpose = F)
> pcx.b.t <- spca.perf(X, "alpha", transpose = T)> lista.spca.b <- list(loadings = (pcx.b$loadings), scores = t(pcx.b$scores), var = 100 *
+ round(pcx.b$eigenvalues/sum(pcx.b$eigenvalues), 2))
> lista.spca.b.t <- list(loadings = (pcx.b.t$scores), scores = pcx.b.t$loadings, var = 100 *
+ round(pcx.b.t$eigenvalues/sum(pcx.b.t$eigenvalues), 2))> g1 <- plotPCA_methods(lista.spca.b, grupos, title1 = "beta scores sparse", title2 = "beta loads sparse",
+ labels.loads = colnames(X), labels.scores = rownames(X))
> g1[[1]]
> g2 <- plotPCA_methods(lista.spca.b.t, grupos, title1 = "beta scores sparse T", title2 = "beta loads sparse T",
+ labels.loads = colnames(X), labels.scores = general_data$Paciente)
>
> g2[[1]]